Regulation of alveolar macrophage p40phox: hierarchy of activating kinases and their inhibition by PGE2

Platelet-Activating Factor-Mediated Endosome Formation Causes Membrane Translocation of p67phox and p40phox That Requires Recruitment and Activation of p38 MAPK, Rab5a, and Phosphatidylinositol 3-Kinase in Human Neutrophils

(2014) N. J. D. McLaughlin et al.   JOURNAL OF IMMUNOLOGY

Molecular regulation of NADPH oxidase 5 via the MAPK pathway

(2011) D. Pandey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Modification of Akt1 by methylglyoxal promotes the proliferation of vascular smooth muscle cells

(2011) Tuanjie Chang et al.   FASEB JOURNAL

Cooperation of p40phoxwith p47phoxfor Nox2-based NADPH Oxidase Activation during Fcγ Receptor (FcγR)-mediated Phagocytosis

(2011) Takehiko Ueyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxiredoxin 6 Phosphorylation and Subsequent Phospholipase A2Activity Are Required for Agonist-mediated Activation of NADPH Oxidase in Mouse Pulmonary Microvascular Endothelium and Alveolar Macrophages

(2011) Shampa Chatterjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Protein Kinase A Anchoring Proteins Direct Prostaglandin E2Modulation of Toll-like Receptor Signaling in Alveolar Macrophages

(2011) Sang-Hoon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emergence of Klebsiella pneumoniae Carbapenemase-Producing Bacteria

(2011) Ryan S. Arnold et al.   SOUTHERN MEDICAL JOURNAL

Akt isoforms differentially regulate neutrophil functions

(2010) J. Chen et al.   BLOOD

Phosphorylation of threonine 154 in p40phox is an important physiological signal for activation of the neutrophil NADPH oxidase

(2010) T. A. M. Chessa et al.   BLOOD

A Key Role for the Phosphorylation of Ser440by the Cyclic AMP-dependent Protein Kinase in Regulating the Activity of the Src Homology 2 Domain-containing Inositol 5′-Phosphatase (SHIP1)

(2010) Jun Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Kinase B (AKT) Mediates Phospholipase D Activation via ERK1/2 and Promotes Respiratory Burst Parameters in Formylpeptide-stimulated Neutrophil-like HL-60 Cells

(2010) Satyananda Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase Inhibition

(2010) Wen-I Wu et al.   PLoS One

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40phox and selective defects in neutrophil NADPH oxidase activity

(2009) J. D. Matute et al.   BLOOD

p47phox, the phagocyte NADPH oxidase/NOX2 organizer: structure, phosphorylation and implication in diseases

(2009) Jamel El-Benna et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

AKAP-independent localization of type-II protein kinase A to dynamic actin microspikes

(2009) Robert L. Rivard et al.   CELL MOTILITY AND THE CYTOSKELETON

Cyclic AMP

(2008) Carlos H. Serezani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Negative Regulation of Class IA Phosphoinositide 3-kinase by Protein Kinase C  Limits Fc  Receptor-Mediated Phagocytosis in Macrophages

(2008) K. Hazeki et al.   JOURNAL OF BIOCHEMISTRY

Phosphoinositide 3-Kinases γ and δ, Linkers of Coordinate C5a Receptor-Fcγ Receptor Activation and Immune Complex-induced Inflammation

(2008) Stephanie Konrad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p110  isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110 

(2008) J. Guillermet-Guibert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA