A helping hand: How vinculin contributes to cell-matrix and cell-cell force transfer

Force-dependent vinculin binding to talin in live cells: a crucial step in anchoring the actin cytoskeleton to focal adhesions

(2014) Hiroaki Hirata et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Actomyosin-dependent formation of the mechanosensitive talin–vinculin complex reinforces actin anchoring

(2014) Corina Ciobanasu et al.   Nature Communications

Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

(2014) Mingxi Yao et al.   Scientific Reports

CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics

(2013) Radoslav Janoštiak et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Vinculin Regulates the Recruitment and Release of Core Focal Adhesion Proteins in a Force-Dependent Manner

(2013) Alex Carisey et al.   CURRENT BIOLOGY

Vinculin Phosphorylation at Tyr1065Regulates Vinculin Conformation and Tension Development in Airway Smooth Muscle Tissues

(2013) Youliang Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vinculin–actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth

(2013) Ingo Thievessen et al.   JOURNAL OF CELL BIOLOGY

Vinculin tension distributions of individual stress fibers within cell-matrix adhesions

(2013) C.-W. Chang et al.   JOURNAL OF CELL SCIENCE

Mechanosensitive systems at the cadherin-F-actin interface

(2013) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

Stimulation of primary osteoblasts with ATP induces transient vinculin clustering at sites of high intracellular traction force

(2013) Toh Weng Tan et al.   JOURNAL OF MOLECULAR HISTOLOGY

Differential Effect of Actomyosin Relaxation on the Dynamic Properties of Focal Adhesion Proteins

(2013) Irena Lavelin et al.   PLoS One

How vinculin regulates force transmission

(2013) D. W. Dumbauld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In situ mechanotransduction via vinculin regulates stem cell differentiation

(2013) Andrew W. Holle et al.   STEM CELLS

Vinculin regulation of F-actin bundle formation

(2013) Caitlin E. Tolbert et al.   Cell Adhesion & Migration

α-catenin, vinculin, and F-actin in strengthening E-cadherin cell–cell adhesions and mechanosensing

(2013) Sylvie Dufour et al.   Cell Adhesion & Migration

α-Catenin Uses a Novel Mechanism to Activate Vinculin

(2012) Xiao Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Catenin and Vinculin Cooperate to Promote High E-cadherin-based Adhesion Strength

(2012) William A. Thomas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling

(2012) Stephan Huveneers et al.   JOURNAL OF CELL BIOLOGY

Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation

(2012) F. Twiss et al.   Biology Open

A mechanism of mechanotransduction at the cell-cell interface

(2011) Shigenobu Yonemura   BIOESSAYS

Myosin II activity dependent and independent vinculin recruitment to the sites of E-cadherin-mediated cell-cell adhesion

(2011) Grant M Sumida et al.   BMC CELL BIOLOGY

Mechanotransduction at cadherin-mediated adhesions

(2011) Deborah E Leckband et al.   CURRENT OPINION IN CELL BIOLOGY

Cadherin–actin interactions at adherens junctions

(2011) Shigenobu Yonemura   CURRENT OPINION IN CELL BIOLOGY

The Vinculin C-terminal Hairpin Mediates F-actin Bundle Formation, Focal Adhesion, and Cell Mechanical Properties

(2011) Kai Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Actomyosin-generated tension controls the molecular kinetics of focal adhesions

(2011) H. Wolfenson et al.   JOURNAL OF CELL SCIENCE

Productive tension: force-sensing and homeostasis of cell–cell junctions

(2011) Guillermo A. Gomez et al.   TRENDS IN CELL BIOLOGY

Molecular Architecture and Function of Matrix Adhesions

(2011) B. Geiger et al.   Cold Spring Harbor Perspectives in Biology

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner

(2010) Quint le Duc et al.   JOURNAL OF CELL BIOLOGY

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Kindlin-1 Is Required for RhoGTPase-Mediated Lamellipodia Formation in Keratinocytes

(2009) Cristina Has et al.   AMERICAN JOURNAL OF PATHOLOGY

Focal adhesion kinase-dependent regulation of adhesive forces involves vinculin recruitment to focal adhesions

(2009) David W. Dumbauld et al.   BIOLOGY OF THE CELL

Anchorage of Vinculin to Lipid Membranes Influences Cell Mechanical Properties

(2009) Gerold Diez et al.   BIOPHYSICAL JOURNAL

Focal Adhesion Kinase Modulates Cell Adhesion Strengthening via Integrin Activation

(2009) Kristin E. Michael et al.   MOLECULAR BIOLOGY OF THE CELL

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Becoming stable and strong: The interplay between vinculin exchange dynamics and adhesion strength during adhesion site maturation

(2009) Christoph Möhl et al.   CELL MOTILITY AND THE CYTOSKELETON