Clinical and molecular characterization of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutations

Identification of Flt3+CD150- myeloid progenitors in adult mouse bone marrow that harbor T lymphoid developmental potential

(2011) A. W. S. Chi et al.   BLOOD

Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

(2011) Irene Homminga et al.   CANCER CELL

Modern Therapy of Acute Lymphoblastic Leukemia

(2011) Renato Bassan et al.   JOURNAL OF CLINICAL ONCOLOGY

Genetic rearrangements in relation to immunophenotype and outcome in T-cell acute lymphoblastic leukaemia

(2010) Jules P.P. Meijerink   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia

(2010) A. Kuhnl et al.   BLOOD

Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL

(2010) R. Jeannet et al.   BLOOD

Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1

(2010) T. D. Ashworth et al.   BLOOD

New Strategies in Acute Lymphoblastic Leukemia: Translating Advances in Genomics into Clinical Practice

(2010) C. G. Mullighan   CLINICAL CANCER RESEARCH

FLT3 inhibition as a targeted therapy for acute myeloid leukemia

(2010) Miguel Sanz et al.   CURRENT OPINION IN ONCOLOGY

Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia

(2010) S. Heesch et al.   HAEMATOLOGICA

Gene expression profiling identifies a subset of adult T-cell acute lymphoblastic leukemia with myeloid-like gene features and over-expression of miR-223

(2010) S. Chiaretti et al.   HAEMATOLOGICA

NOTCH mutations as prognostic markers in T-ALL

(2010) A Ferrando   LEUKEMIA

BAALC-associated gene expression profiles define IGFBP7 as a novel molecular marker in acute leukemia

(2010) S Heesch et al.   LEUKEMIA

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols

(2010) L Zuurbier et al.   LEUKEMIA

NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951

(2010) E Clappier et al.   LEUKEMIA

The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL–BFM 2000 protocol can be separated from FBXW7 loss of function

(2010) C Kox et al.   LEUKEMIA

WT1 mutations in T-ALL

(2009) V. Tosello et al.   BLOOD

T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)

(2009) D. I. Marks et al.   BLOOD

T-cell acute lymphoblastic leukemia

(2009) S. Chiaretti et al.   HAEMATOLOGICA

Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia

(2009) C. D. Baldus et al.   HAEMATOLOGICA

GATA-3 is required for early T lineage progenitor development

(2009) Tomonori Hosoya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

(2009) Elaine Coustan-Smith et al.   LANCET ONCOLOGY

Wilms tumor 1 (WT1) gene mutations in pediatric T-cell malignancies

(2009) A Renneville et al.   LEUKEMIA

Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B and 14 for childhood acute lymphoblastic leukemia

(2009) C H Pui et al.   LEUKEMIA

Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000

(2009) A Möricke et al.   LEUKEMIA

T-cell lymphoblastic leukemia in early childhood presents NOTCH1 mutations and MLL rearrangements

(2009) Marcela Braga Mansur et al.   LEUKEMIA RESEARCH

Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras–initiated leukemia

(2008) Mark Y. Chiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutation of the Wilms’ Tumor 1 Gene Is a Poor Prognostic Factor Associated With Chemotherapy Resistance in Normal Karyotype Acute Myeloid Leukemia: The United Kingdom Medical Research Council Adult Leukaemia Working Party

(2008) Priya Virappane et al.   JOURNAL OF CLINICAL ONCOLOGY

Wilms’ Tumor 1 Gene Mutations Independently Predict Poor Outcome in Adults With Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

(2008) Peter Paschka et al.   JOURNAL OF CLINICAL ONCOLOGY

The earliest thymic progenitors for T cells possess myeloid lineage potential

(2008) J. Jeremiah Bell et al.   NATURE

Treatment of Adult Acute Lymphoblastic Leukemia

(2008) Nicola Gökbuget et al.   SEMINARS IN HEMATOLOGY