Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL

Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1

(2010) T. D. Ashworth et al.   BLOOD

A clustering approach for identification of enriched domains from histone modification ChIP-Seq data

(2009) Chongzhi Zang et al.   BIOINFORMATICS

Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A

(2009) Y. Yashiro-Ohtani et al.   GENES & DEVELOPMENT

Genetic inactivation of Ikaros is a rare event in human T-ALL

(2009) Ambroise Marçais et al.   LEUKEMIA RESEARCH

Ikaros Directly Represses the Notch Target GeneHes1in a Leukemia T Cell Line

(2008) Katie L. Kathrein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras–initiated leukemia

(2008) Mark Y. Chiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Acute lymphoblastic leukaemia

(2008) Ching-Hon Pui et al.   LANCET

Ikaros Represses the Transcriptional Response to Notch Signaling in T-Cell Development

(2008) E. Kleinmann et al.   MOLECULAR AND CELLULAR BIOLOGY