Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model
Authors
Keywords
-
Journal
Nature Communications
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2014-08-01
DOI
10.1038/ncomms5563
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Brain MR spectroscopic abnormalities in “MRI-negative” tuberous sclerosis complex patients
- (2013) William E. Wu et al. EPILEPSY & BEHAVIOR
- Excitatory/Inhibitory Synaptic Imbalance Leads to Hippocampal Hyperexcitability in Mouse Models of Tuberous Sclerosis
- (2013) Helen S. Bateup et al. NEURON
- A call for transparent reporting to optimize the predictive value of preclinical research
- (2012) Story C. Landis et al. NATURE
- Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex
- (2012) Atsushi Sato et al. Nature Communications
- Excitatory neuronal connectivity in the barrel cortex
- (2012) Dirk Feldmeyer Frontiers in Neuroanatomy
- An Emerging Role for the Mammalian Target of Rapamycin in “Pathological” Protein Translation: Relevance to Cocaine Addiction
- (2012) Christopher V. Dayas et al. Frontiers in Pharmacology
- The NMDA receptor complex as a therapeutic target in epilepsy: a review
- (2011) Mehdi Ghasemi et al. EPILEPSY & BEHAVIOR
- Mammalian target of rapamycin (mTOR) activation in focal cortical dysplasia and related focal cortical malformations
- (2011) Michael Wong EXPERIMENTAL NEUROLOGY
- TSC1/TSC2 signaling in the CNS
- (2011) Juliette M. Han et al. FEBS LETTERS
- Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice
- (2011) David M. Feliciano et al. JOURNAL OF CLINICAL INVESTIGATION
- A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior
- (2011) M Carlén et al. MOLECULAR PSYCHIATRY
- Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin
- (2011) Itzamarie Chévere-Torres et al. NEUROBIOLOGY OF DISEASE
- Analysis of TSC Cortical Tubers by Deep Sequencing of TSC1, TSC2 and KRAS Demonstrates that Small Second-Hit Mutations in these Genes are Rare Events
- (2010) Wei Qin et al. BRAIN PATHOLOGY
- Tsc2-Rheb signaling regulates EphA-mediated axon guidance
- (2010) Duyu Nie et al. NATURE NEUROSCIENCE
- Biallelic TSC gene inactivation in tuberous sclerosis complex
- (2010) P. B. Crino et al. NEUROLOGY
- Role of mutational analysis in diagnosis of tuberous sclerosis complex
- (2009) EA Vail et al. CLINICAL GENETICS
- The natural history of epilepsy in tuberous sclerosis complex
- (2009) Catherine J. Chu-Shore et al. EPILEPSIA
- Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse
- (2009) S. W. Way et al. HUMAN MOLECULAR GENETICS
- Unusual Clinical Presentation of Tuberless Tuberous Sclerosis Complex
- (2009) Rami Kaufmann et al. JOURNAL OF CHILD NEUROLOGY
- N-Methyl-D-aspartate (NMDA) Receptor NR2 Subunit Selectivity of a Series of Novel Piperazine-2,3-dicarboxylate Derivatives: Preferential Blockade of Extrasynaptic NMDA Receptors in the Rat Hippocampal CA3-CA1 Synapse
- (2009) B. M. Costa et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Neurons that Fire Together Also Conspire Together: Is Normal Sleep Circuitry Hijacked to Generate Epilepsy?
- (2009) Mark P. Beenhakker et al. NEURON
- The Excitatory Neuronal Network of the C2 Barrel Column in Mouse Primary Somatosensory Cortex
- (2009) Sandrine Lefort et al. NEURON
- NMDA Receptor Hypofunction Leads to Generalized and Persistent Aberrant γ Oscillations Independent of Hyperlocomotion and the State of Consciousness
- (2009) Tahir Hakami et al. PLoS One
- Cell-specific alterations of glutamate receptor expression in tuberous sclerosis complex cortical tubers
- (2008) Delia M. Talos et al. ANNALS OF NEUROLOGY
- Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
- (2008) Ling-Hui Zeng et al. ANNALS OF NEUROLOGY
- Are cortical tubers epileptogenic? Evidence from electrocorticography
- (2008) Philippe Major et al. EPILEPSIA
- Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and Function
- (2008) L. Meikle et al. JOURNAL OF NEUROSCIENCE
- Tuberous sclerosis
- (2008) Paolo Curatolo et al. LANCET
- Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis
- (2008) Dan Ehninger et al. NATURE MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started