Relative motions between left flipper and dorsal fin domains favour P2X4 receptor activation

Unanticipated parallels in architecture and mechanism between ATP-gated P2X receptors and acid sensing ion channels

(2013) Isabelle Baconguis et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Inter- and intrasubunit interactions between transmembrane helices in the open state of P2X receptor channels

(2013) G. Heymann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tightening of the ATP-binding sites induces the opening of P2X receptor channels

(2012) Ruotian Jiang et al.   EMBO JOURNAL

Highly Conserved Salt Bridge Stabilizes Rigid Signal Patch at Extracellular Loop Critical for Surface Expression of Acid-sensing Ion Channels

(2012) Yang Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

(2012) Motoyuki Hattori et al.   NATURE

Gating mechanism of a P2X4 receptor developed from normal mode analysis and molecular dynamics simulations

(2012) J. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor

(2012) E. Lorinczi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel

(2012) J. A. Roberts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Moving through the gate in ATP-activated P2X receptors

(2012) Ruotian Jiang et al.   TRENDS IN BIOCHEMICAL SCIENCES

ProDy: Protein Dynamics Inferred from Theory and Experiments

(2011) A. Bakan et al.   BIOINFORMATICS

Atomic Level Characterization of the Nonproton Ligand-sensing Domain of ASIC3 Channels

(2011) Ye Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation and Regulation of Purinergic P2X Receptor Channels

(2011) C. Coddou et al.   PHARMACOLOGICAL REVIEWS

A Nonproton Ligand Sensor in the Acid-Sensing Ion Channel

(2010) Ye Yu et al.   NEURON

Molecular basis of cyclooxygenase enzymes (COXs) selective inhibition

(2010) V. Limongelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New structure enlivens interest in P2X receptors

(2010) Liam E. Browne et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE

Direct Observation of ATP-Induced Conformational Changes in Single P2X4 Receptors

(2009) Youichi Shinozaki et al.   PLOS BIOLOGY

Signaling at Purinergic P2X Receptors

(2008) Annmarie Surprenant et al.   Annual Review of Physiology

Metadynamics: a method to simulate rare events and reconstruct the free energy in biophysics, chemistry and material science

(2008) Alessandro Laio et al.   REPORTS ON PROGRESS IN PHYSICS