Tightening of the ATP-binding sites induces the opening of P2X receptor channels

Dynamics and allosteric potential of the AMPA receptor N-terminal domain

(2011) Madhav Sukumaran et al.   EMBO JOURNAL

Zinc enhances long-term potentiation through P2X receptor modulation in the hippocampal CA1 region

(2011) Ramón A. Lorca et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

Agonist trapped in ATP-binding sites of the P2X2 receptor

(2011) R. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binding Leverage as a Molecular Basis for Allosteric Regulation

(2011) Simon Mitternacht et al.   PLoS Computational Biology

Structural interpretation of P2X receptor mutagenesis studies on drug action

(2010) Richard J Evans   BRITISH JOURNAL OF PHARMACOLOGY

Gated Access to the Pore of a P2X Receptor

(2010) Sebastian Kracun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Putative Extracellular Salt Bridge at the Subunit Interface Contributes to the Ion Channel Function of the ATP-gated P2X2 Receptor

(2010) Ruotian Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P2X receptor channels show threefold symmetry in ionic charge selectivity and unitary conductance

(2010) Liam E Browne et al.   NATURE NEUROSCIENCE

New structure enlivens interest in P2X receptors

(2010) Liam E. Browne et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Pore-opening mechanism in trimeric P2X receptor channels

(2010) Mufeng Li et al.   Nature Communications

Gating Transition of Pentameric Ligand-Gated Ion Channels

(2009) Fangqiang Zhu et al.   BIOPHYSICAL JOURNAL

Polar Residues in the Second Transmembrane Domain of the Rat P2X2 Receptor That Affect Spontaneous Gating, Unitary Conductance, and Rectification

(2009) L. Cao et al.   JOURNAL OF NEUROSCIENCE

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

(2009) Alexander I. Sobolevsky et al.   NATURE

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE

P2X receptors: dawn of the post-structure era

(2009) Mark T. Young   TRENDS IN BIOCHEMICAL SCIENCES

Inherent Dynamics of the Acid-Sensing Ion Channel 1 Correlates with the Gating Mechanism

(2009) Huaiyu Yang et al.   PLOS BIOLOGY

Contribution of extracellular negatively charged residues to ATP action and zinc modulation of rat P2X2receptors

(2008) Sean C. Friday et al.   JOURNAL OF NEUROCHEMISTRY

Opposite Effects of Zinc on Human and Rat P2X2 Receptors

(2008) R. K. Tittle et al.   JOURNAL OF NEUROSCIENCE

Gating the pore of P2X receptor channels

(2008) Mufeng Li et al.   NATURE NEUROSCIENCE

Purinergic signalling and disorders of the central nervous system

(2008) Geoffrey Burnstock   NATURE REVIEWS DRUG DISCOVERY

ATP-gated P2X cation-channels

(2008) Michael F. Jarvis et al.   NEUROPHARMACOLOGY

Zinc at glutamatergic synapses

(2008) P. Paoletti et al.   NEUROSCIENCE

ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site

(2007) Sahil Adriouch et al.   FASEB JOURNAL