Rhein Reduces Fat Weight indb/dbMouse and Prevents Diet-Induced Obesity in C57Bl/6 Mouse through the Inhibition of PPARγSignaling

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Rhein, an inhibitor of adipocyte differentiation and adipogenesis

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National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

(2011) Mariel M Finucane et al.   LANCET

PPARs: diverse regulators in energy metabolism and metabolic diseases

(2010) Yong-Xu Wang   CELL RESEARCH

Genetic Link Between Obesity and MMP14-Dependent Adipogenic Collagen Turnover

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Orexin receptor antagonists: a review of promising compounds patented since 2006

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Discovery of the Dual Orexin Receptor Antagonist [(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia

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(2010) G.A. Kennett et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Regulatory challenges for new drugs to treat obesity and comorbid metabolic disorders

(2009) David J. Heal et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Mechanism of the anti-obesity effects induced by a novel Melanin-concentrating hormone 1-receptor antagonist in mice

(2009) Masahiko Ito et al.   BRITISH JOURNAL OF PHARMACOLOGY

Discontinuation due to adverse events in randomized trials of orlistat, sibutramine and rimonabant: a meta-analysis

(2009) K. Johansson et al.   Obesity Reviews

The Role of Tanshinone IIA in the Treatment of Obesity through Peroxisome Proliferator-Activated Receptor γ Antagonism

(2008) Zhenwei Gong et al.   ENDOCRINOLOGY