IL13 activates autophagy to regulate secretion in airway epithelial cells

Autophagic proteins regulate cigarette smoke induced apoptosis: Protective role of heme oxygenase-1

(2014) Hong Pyo Kim et al.   Autophagy

NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion

(2014) Marta Wlodarska et al.   CELL

Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer’s disease-linked presenilin 1 A246E mutation can be reversed with cAMP

(2014) E.E. Coffey et al.   NEUROSCIENCE

Rho-Associated Protein Kinase Inhibition Enhances Airway Epithelial Basal-Cell Proliferation and Lentivirus Transduction

(2013) Amjad Horani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

(2013) Khushbu K Patel et al.   EMBO JOURNAL

Autophagy and Cellular Immune Responses

(2013) Yuting Ma et al.   IMMUNITY

IL-33 is more potent than IL-25 in provoking IL-13–producing nuocytes (type 2 innate lymphoid cells) and airway contraction

(2013) Jillian L. Barlow et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Long-term IL-33–producing epithelial progenitor cells in chronic obstructive lung disease

(2013) Derek E. Byers et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of Membrane Association and Atg14-Dependent Phosphorylation in Beclin-1-Mediated Autophagy

(2013) A. I. Fogel et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor

(2013) Takehiro Torisu et al.   NATURE MEDICINE

LRRC6 Mutation Causes Primary Ciliary Dyskinesia with Dynein Arm Defects

(2013) Amjad Horani et al.   PLoS One

Chronic IL9 and IL-13 Exposure Leads to an Altered Differentiation of Ciliated Cells in a Well-Differentiated Paediatric Bronchial Epithelial Cell Model

(2013) Jeremy C. Parker et al.   PLoS One

CCDC65 Mutation Causes Primary Ciliary Dyskinesia with Normal Ultrastructure and Hyperkinetic Cilia

(2013) Amjad Horani et al.   PLoS One

Targeting autophagy

(2012) Sharon M. Gorski et al.   Autophagy

ATG5, autophagy and lung function in asthma

(2012) Audrey Poon et al.   Autophagy

Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila

(2012) J. Burgess et al.   DEVELOPMENT

The inhibition of aldose reductase on mucus production induced by interleukin-13 in the human bronchial epithelial cells

(2012) Depeng Jiang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

IL-13 in asthma and allergic disease: Asthma phenotypes and targeted therapies

(2012) Jennifer L. Ingram et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Autophagy Is a Protective Mechanism for Human Melanoma Cells under Acidic Stress

(2012) Maria Lucia Marino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-13–induced airway mucus production is attenuated by MAPK13 inhibition

(2012) Yael G. Alevy et al.   JOURNAL OF CLINICAL INVESTIGATION

Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens

(2012) Michael J. Holtzman   JOURNAL OF CLINICAL INVESTIGATION

Helminth Infection Impairs Autophagy-Mediated Killing of Bacterial Enteropathogens by Macrophages

(2012) C.-w. Su et al.   JOURNAL OF IMMUNOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery

(2012) Dhara A. Patel et al.   PLoS One

Functional Variant in the Autophagy-Related 5 Gene Promotor is Associated with Childhood Asthma

(2012) Lisa J. Martin et al.   PLoS One

Hyperoxia-Induced LC3B Interacts with the Fas Apoptotic Pathway in Epithelial Cell Death

(2011) Akihiko Tanaka et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Principles and Current Strategies for Targeting Autophagy for Cancer Treatment

(2011) R. K. Amaravadi et al.   CLINICAL CANCER RESEARCH

Autophagy and cytokines

(2011) James Harris   CYTOKINE

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

(2011) Carl J. DeSelm et al.   DEVELOPMENTAL CELL

Crucial role for autophagy in degranulation of mast cells

(2011) Hiroko Ushio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Innate IL-13–producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity

(2011) Jillian L. Barlow et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

RETRACTED: REDOX regulation of IL-13 signaling in intestinal epithelial cells: Usage of alternate pathways mediates distinct gene expression patterns

(2010) Debasmita Mandal et al.   CELLULAR SIGNALLING

Rhinovirus induces MUC5AC in a human infection model and in vitro via NF- B and EGFR pathways

(2010) C. A. Hewson et al.   EUROPEAN RESPIRATORY JOURNAL

IL-33 Exacerbates Eosinophil-Mediated Airway Inflammation

(2010) B. Stolarski et al.   JOURNAL OF IMMUNOLOGY

Autophagy in Atherosclerosis

(2009) Wim Martinet et al.   CIRCULATION RESEARCH

Regulation of Airway MUC5AC Expression by IL-1  and IL-17A; the NF- B Paradigm

(2009) T. Fujisawa et al.   JOURNAL OF IMMUNOLOGY

The role of autophagy in Paneth cell differentiation and secretion

(2009) T S Stappenbeck   Mucosal Immunology

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

Interleukin-4, Interleukin-13, Signal Transducer and Activator of Transcription Factor 6, and Allergic Asthma

(2008) Douglas Kuperman et al.   CURRENT MOLECULAR MEDICINE

Mucus hypersecretion in asthma: causes and effects

(2008) Christopher M Evans et al.   CURRENT OPINION IN PULMONARY MEDICINE

Toll-like receptors control autophagy

(2008) Mónica A Delgado et al.   EMBO JOURNAL

Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system

(2008) Y. Kondo et al.   INTERNATIONAL IMMUNOLOGY

The cytokine network in asthma and chronic obstructive pulmonary disease

(2008) Peter J. Barnes   JOURNAL OF CLINICAL INVESTIGATION

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease

(2008) Edy Y Kim et al.   NATURE MEDICINE

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

(2008) Zhi-Hua Chen et al.   PLoS One

Regulated Airway Goblet Cell Mucin Secretion

(2007) C. William Davis et al.   Annual Review of Physiology