MicroRNA-29a Alleviates Bile Duct Ligation Exacerbation of Hepatic Fibrosis in Mice through Epigenetic Control of Methyltransferases

Epigenetics in liver disease: from biology to therapeutics

(2016) Timothy Hardy et al.   GUT

MicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signaling

(2016) Jeongeun Hyun et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Pharmacological Intervention in Hepatic Stellate Cell Activation and Hepatic Fibrosis

(2016) Hans-Theo Schon et al.   Frontiers in Pharmacology

Regulatory Effects and Mechanism of Adenovirus-Mediated PTEN Gene on Hepatic Stellate Cells

(2015) Junyan An et al.   DIGESTIVE DISEASES AND SCIENCES

Deregulation of DNMT1, DNMT3B and miR-29s in Burkitt lymphoma suggests novel contribution for disease pathogenesis

(2015) Marcela C. Robaina et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Immunohistochemical characterization of glial fibrillary acidic protein (GFAP)-expressing cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA)

(2015) Anusha Hemamali Tennakoon et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Non-coding RNA-mediated epigenetic regulation of liver fibrosis

(2015) Jing-Jing Yang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

New therapies for hepatic fibrosis

(2015) Yukinori Koyama et al.   Clinics and Research in Hepatology and Gastroenterology

Activation of Mir-29a in Activated Hepatic Stellate Cells Modulates Its Profibrogenic Phenotype through Inhibition of Histone Deacetylases 4

(2015) Ying-Hsien Huang et al.   PLoS One

MicroRNA-29a protects against acute liver injury in a mouse model of obstructive jaundice via inhibition of the extrinsic apoptosis pathway

(2013) Mao-Meng Tiao et al.   APOPTOSIS

Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation - a novel mechanism suppressing liver fibrosis

(2013) Jianjian Zheng et al.   FEBS Journal

Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice

(2013) Grace Chappell et al.   INTERNATIONAL JOURNAL OF CANCER

Epigenetic histone methylation regulates transforming growth factor β-1 expression following bile duct ligation in rats

(2013) Shyr-Ming Sheen-Chen et al.   JOURNAL OF GASTROENTEROLOGY

Toll-like receptor 3 (TLR3) activation induces microRNA-dependent reexpression of functional RAR  and tumor regression

(2013) R. Galli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective activation of Toll-like receptor 7 in activated hepatic stellate cells may modulate their profibrogenic phenotype

(2012) Ming-Huei Chou et al.   BIOCHEMICAL JOURNAL

Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation

(2012) Maria Jesus Perugorria et al.   HEPATOLOGY

Morphogens and hepatic stellate cell fate regulation in chronic liver disease

(2012) Hidekazu Tsukamoto et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

DNMT1-mediated PTEN hypermethylation confers hepatic stellate cell activation and liver fibrogenesis in rats

(2012) Er-Bao Bian et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tissue factor dependent liver injury causes release of retinoid receptors (RXR-α and RAR-α) as lipid droplets

(2011) Mohamed Sadek Abdel-Bakky et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture

(2011) Sarmistha Bandyopadhyay et al.   JOURNAL OF INFECTIOUS DISEASES

Hepatocyte Growth Factor (HGF) Inhibits Collagen I and IV Synthesis in Hepatic Stellate Cells by miRNA-29 Induction

(2011) Monika Kwiecinski et al.   PLoS One

Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis

(2010) Christoph Roderburg et al.   HEPATOLOGY

Evolving challenges in hepatic fibrosis

(2010) Scott L. Friedman   Nature Reviews Gastroenterology & Hepatology

Cholestasis downregulate hepcidin expression through inhibiting IL-6-induced phosphorylation of signal transducer and activator of transcription 3 signaling

(2009) Ying-Hsien Huang et al.   LABORATORY INVESTIGATION

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY