Sublytic C5b-9 triggers glomerular mesangial cell apoptosis via XAF1 gene activation mediated by p300-dependent IRF-1 acetylation

Cocaine-Associated Retiform Purpura

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The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation

(2013) K. Triantafilou et al.   JOURNAL OF CELL SCIENCE

Role of p300 in regulating neuronal nitric oxide synthase gene expression through nuclear factor-κB-mediated way in neuronal cells

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Dual Involvement of Growth Arrest-Specific Gene 6 in the Early Phase of Human IgA Nephropathy

(2013) Kojiro Nagai et al.   PLoS One

Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven Transcription

(2013) Sulakshana P. Mukherjee et al.   PLOS BIOLOGY

Inhibition of LDH-A by lentivirus-mediated small interfering RNA suppresses intestinal-type gastric cancer tumorigenicity through the downregulation of Oct4

(2012) Yongjie Zhang et al.   CANCER LETTERS

The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3

(2012) Ian M. Love et al.   CELL CYCLE

The Acetylase/Deacetylase Couple CREB-binding Protein/Sirtuin 1 Controls Hypoxia-inducible Factor 2 Signaling

(2012) Rui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sublytic C5b-9 Complexes Induce Apoptosis of Glomerular Mesangial Cells in Rats with Thy-1 Nephritis through Role of Interferon Regulatory Factor-1-dependent Caspase 8 Activation

(2012) Lisha Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interferon Regulatory Factor 1 Transactivates Expression of Human DNA Polymerase η in Response to CarcinogenN-Methyl-N′-nitro-N-nitrosoguanidine

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Interactions Between β-Catenin and Transforming Growth Factor-β Signaling Pathways Mediate Epithelial-Mesenchymal Transition and Are Dependent on the Transcriptional Co-activator cAMP-response Element-binding Protein (CREB)-binding Protein (CBP)

(2012) Beiyun Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E2A and CBP/p300 Act in Synergy To Promote Chromatin Accessibility of the Immunoglobulin   Locus

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Abated microRNA-195 expression protected mesangial cells from apoptosis in early diabetic renal injury in mice

(2012) Yu Q. Chen et al.   JOURNAL OF NEPHROLOGY

The IgA1 immune complex–mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy

(2012) Houda Tamouza et al.   KIDNEY INTERNATIONAL

Regulation of Nuclear Factor κB (NF-κB) Transcriptional Activity via p65 Acetylation by the Chaperonin Containing TCP1 (CCT)

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Transcriptional Regulation of PES1 Expression by c-Jun in Colon Cancer

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Association of expression of XIAP-associated factor 1 (XAF1) with clinicopathologic factors, overall survival, microvessel density and cisplatin-resistance in ovarian cancer

(2012) YunXia Wang et al.   REGULATORY PEPTIDES

XAF1 is frequently methylated in human esophageal cancer

(2012) Xiang-Yu Chen   WORLD JOURNAL OF GASTROENTEROLOGY

p53 Regulates Cell Cycle and MicroRNAs to Promote Differentiation of Human Embryonic Stem Cells

(2012) Abhinav K. Jain et al.   PLOS BIOLOGY

Preferential Genome Targeting of the CBP Co-Activator by Rel and Smad Proteins in Early Drosophila melanogaster Embryos

(2012) Per-Henrik Holmqvist et al.   PLoS Genetics

Change of MAX Interactor 1 Expression in an Anti-Thy1 Nephritis Model and its Effect on Mesangial Cell Proliferation

(2011) Xiaoluan Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Activating transcription factor 3 (ATF3) promotes sublytic C5b-9-induced glomerular mesangial cells apoptosis through up-regulation of Gadd45α and KLF6 gene expression

(2011) Kuanfeng Xu et al.   IMMUNOBIOLOGY

Modulation of FoxO1 phosphorylation/acetylation by baicalin during aging

(2011) Dae Hyun Kim et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Sublytic C5b-9 complexes induce proliferative changes of glomerular mesangial cells in rat Thy-1 nephritis through TRAF6-mediated PI3K-dependent Akt1 activation

(2011) Wen Qiu et al.   JOURNAL OF PATHOLOGY

XIAP-associated factor 1 (XAF1), a novel target of p53, enhances p53-mediated apoptosis via post-translational modification

(2011) Bing Zou et al.   MOLECULAR CARCINOGENESIS

Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma

(2011) Purushottam Jha et al.   MOLECULAR IMMUNOLOGY

Activation of Src Mediates PDGF-Induced Smad1 Phosphorylation and Contributes to the Progression of Glomerulosclerosis in Glomerulonephritis

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Excretion of complement proteins and its activation marker C5b-9 in IgA nephropathy in relation to renal function

(2011) Kisara Onda et al.   BMC Nephrology

Tumor suppressor XIAP-Associated factor 1 (XAF1) cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression

(2010) Shui Ping Tu et al.   CANCER

Cigarette smoke extract regulates cytosolic phospholipase A2expression via NADPH oxidase/MAPKs/AP-1 and p300 in human tracheal smooth muscle cells

(2010) Shin-Ei Cheng et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Development of an optimized RNA-based murine norovirus reverse genetics system

(2010) Muhammad Amir Yunus et al.   JOURNAL OF VIROLOGICAL METHODS

Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1

(2010) S Sengupta et al.   ONCOGENE

Interferon Regulatory Factor 1 Mediates Acetylation and Release of High Mobility Group Box 1 from Hepatocytes During Murine Liver Ischemia-Reperfusion Injury

(2010) Rajeev Dhupar et al.   SHOCK

IRF-1 transcriptionally upregulates PUMA, which mediates the mitochondrial apoptotic pathway in IRF-1-induced apoptosis in cancer cells

(2009) J Gao et al.   CELL DEATH AND DIFFERENTIATION

Apoptosis of glomerular mesangial cells induced by sublytic C5b-9 complexes in rats with Thy-1 nephritis is dependent on Gadd45γ upregulation

(2009) Wen Qiu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Response gene to complement 32 is required for C5b-9 induced cell cycle activation in endothelial cells

(2009) Matthew Fosbrink et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

c-Jun N-terminal kinase (JNK1) upregulates XIAP-associated factor 1 (XAF1) through interferon regulatory factor 1 (IRF-1) in gastrointestinal cancer

(2008) J. Wang et al.   CARCINOGENESIS

Nestin expression in repopulating mesangial cells promotes their proliferation

(2008) Christoph Daniel et al.   LABORATORY INVESTIGATION

PCAF Acetylates β-Catenin and Improves Its Stability

(2008) Xinjian Ge et al.   MOLECULAR BIOLOGY OF THE CELL

Role of apoptosis signal-regulating kinase 1 in complement-mediated glomerular epithelial cell injury

(2008) Guohui Ren et al.   MOLECULAR IMMUNOLOGY

Mesangial C4d deposition: a new prognostic factor in IgA nephropathy

(2008) M. Espinosa et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

C5b-9 glomerular deposition and tubular α3β1-integrin expression are implicated in the development of chronic lesions and predict renal function outcome in immunoglobulin A nephropathy

(2008) Maria Stangou et al.   SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY