Biogeochemical Forces Shape the Composition and Physiology of Polymicrobial Communities in the Cystic Fibrosis Lung

The Pseudomonas Toxin Pyocyanin Inhibits the Dual Oxidase-Based Antimicrobial System as It Imposes Oxidative Stress on Airway Epithelial Cells

(2014) B. Rada et al.   JOURNAL OF IMMUNOLOGY

Cystic Fibrosis Therapy: A Community Ecology Perspective

(2013) Douglas Conrad et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Abundant DNase I-Sensitive Bacterial DNA in Healthy Porcine Lungs and Its Implications for the Lung Microbiome

(2013) Alejandro A. Pezzulo et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Clinical Insights from Metagenomic Analysis of Sputum Samples from Patients with Cystic Fibrosis

(2013) Y. W. Lim et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Rapid 16S rRNA Next-Generation Sequencing of Polymicrobial Clinical Samples for Diagnosis of Complex Bacterial Infections

(2013) Stephen J. Salipante et al.   PLoS One

Ferrous Iron Is a Significant Component of Bioavailable Iron in Cystic Fibrosis Airways

(2013) R. C. Hunter et al.   mBio

Phenazine Content in the Cystic Fibrosis Respiratory Tract Negatively Correlates with Lung Function and Microbial Complexity

(2012) Ryan C. Hunter et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Distribution of nitrogen fixation and nitrogenase-like sequences amongst microbial genomes

(2012) Patricia C Dos Santos et al.   BMC GENOMICS

Metabolic adaptations ofPseudomonas aeruginosaduring cystic fibrosis chronic lung infections

(2012) V. Behrends et al.   ENVIRONMENTAL MICROBIOLOGY

Recent insights into the diversity, frequency and ecological roles of phenazines in fluorescentPseudomonasspp.

(2012) Dmitri V. Mavrodi et al.   ENVIRONMENTAL MICROBIOLOGY

Role of glutamate metabolism in bacterial responses towards acid and other stresses

(2012) C. Feehily et al.   JOURNAL OF APPLIED MICROBIOLOGY

108 First identification of non-lactose fermenting Gram negative respiratory isolates from an Irish cystic fibrosis population using matrix-assisted laser desorption ionisation-time of flight mass spectrometry (MALDI-TOF MS)

(2012) A.-R. Prior et al.   Journal of Cystic Fibrosis

Metagenomics and metatranscriptomics: Windows on CF-associated viral and microbial communities

(2012) Yan Wei Lim et al.   Journal of Cystic Fibrosis

Iron accumulates in the lavage and explanted lungs of cystic fibrosis patients

(2012) Andrew J. Ghio et al.   Journal of Cystic Fibrosis

Desulfurization of mucin by Pseudomonas aeruginosa: influence of sulfate in the lungs of cystic fibrosis patients

(2012) C. V. Robinson et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

(2012) Alejandro A. Pezzulo et al.   NATURE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Identifying Low pH Active and Lactate-Utilizing Taxa within Oral Microbiome Communities from Healthy Children Using Stable Isotope Probing Techniques

(2012) Jeffrey S. McLean et al.   PLoS One

The Airway Microbiota in Cystic Fibrosis: A Complex Fungal and Bacterial Community—Implications for Therapeutic Management

(2012) Laurence Delhaes et al.   PLoS One

Direct sampling of cystic fibrosis lungs indicates that DNA-based analyses of upper-airway specimens can misrepresent lung microbiota

(2012) A. F. Goddard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interkingdom metabolic transformations captured by microbial imaging mass spectrometry

(2012) W. J. Moree et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decade-long bacterial community dynamics in cystic fibrosis airways

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Reconstruction for Metagenomic Data and Its Application to the Human Microbiome

(2012) Sahar Abubucker et al.   PLoS Computational Biology

Topographical Continuity of Bacterial Populations in the Healthy Human Respiratory Tract

(2011) Emily S. Charlson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Oxidative stress and antioxidant therapy in cystic fibrosis

(2011) Francesco Galli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Quality control and preprocessing of metagenomic datasets

(2011) R. Schmieder et al.   BIOINFORMATICS

The polymicrobial nature of airway infections in cystic fibrosis: Cangene Gold Medal LectureThis article is based on a presentation by Dr. Christopher Sibley at the 60th Annual Meeting of the Canadian Society of Microbiologists in Hamilton, Ontario, on 15 June 2010. Dr. Sibley was the recipient of the 2010 Cangene Gold Medal as the Canadian Graduate Student Microbiologist of the Year, an annual award sponsored by Cangene Corporation intended to recognize excellence in graduate research.

(2011) Christopher D. Sibley et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase

(2011) Usheer Kanjee et al.   EMBO JOURNAL

Serine Proteases Degrade Airway Mucins in Cystic Fibrosis

(2011) Markus O. Henke et al.   INFECTION AND IMMUNITY

Fast Identification and Removal of Sequence Contamination from Genomic and Metagenomic Datasets

(2011) Robert Schmieder et al.   PLoS One

A Molecular Mechanism for Bacterial Susceptibility to Zinc

(2011) Christopher A. McDevitt et al.   PLoS Pathogens

Role of epithelial HCO3− transport in mucin secretion: lessons from cystic fibrosis

(2010) Paul M. Quinton   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Metabolism and function of phenazines in bacteria: impacts on the behavior of bacteria in the environment and biotechnological processes

(2010) Leland S. Pierson et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis

(2010) Eline Thomson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Anaerobic physiology of Pseudomonas aeruginosa in the cystic fibrosis lung

(2010) Max Schobert et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Adaptation of Pseudomonas aeruginosa during persistence in the cystic fibrosis lung

(2010) Michael Hogardt et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Gene expression of Pseudomonas aeruginosa in a mucin-containing synthetic growth medium mimicking cystic fibrosis lung sputum

(2010) C. Fung et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Lipoic Acid Metabolism in Microbial Pathogens

(2010) M. D. Spalding et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Nutrient Availability as a Mechanism for Selection of Antibiotic Tolerant Pseudomonas aeruginosa within the CF Airway

(2010) Lucas R. Hoffman et al.   PLoS Pathogens

Sputum Trace Metals Are Biomarkers of Inflammatory and Suppurative Lung Disease

(2009) Robert D. Gray et al.   CHEST

Antibiotic-resistant obligate anaerobes during exacerbations of cystic fibrosis patients

(2009) D. Worlitzsch et al.   CLINICAL MICROBIOLOGY AND INFECTION

Occurrence of phosphate acquisition genes inProchlorococcuscells from different ocean regions

(2009) Adam C. Martiny et al.   ENVIRONMENTAL MICROBIOLOGY

Endogenous Phenazine Antibiotics Promote Anaerobic Survival of Pseudomonas aeruginosa via Extracellular Electron Transfer

(2009) Y. Wang et al.   JOURNAL OF BACTERIOLOGY

Oral Biofilms: Emerging Concepts in Microbial Ecology

(2009) S. Filoche et al.   JOURNAL OF DENTAL RESEARCH

Dietary nitrate – Good or bad?

(2009) Mark Gilchrist et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Exhaled breath condensate pH and ammonia in cystic fibrosis and response to treatment of acute pulmonary exacerbations

(2009) Sharon Newport et al.   PEDIATRIC PULMONOLOGY

Pseudomonas aeruginosabiofilms in the respiratory tract of cystic fibrosis patients

(2009) Thomas Bjarnsholt et al.   PEDIATRIC PULMONOLOGY

Metagenomic Analysis of Respiratory Tract DNA Viral Communities in Cystic Fibrosis and Non-Cystic Fibrosis Individuals

(2009) Dana Willner et al.   PLoS One

Proteases and cystic fibrosis

(2008) J VOYNOW et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis

(2008) Paul M Quinton   LANCET

Functional metagenomic profiling of nine biomes

(2008) Elizabeth A. Dinsdale et al.   NATURE

A polymicrobial perspective of pulmonary infections exposes an enigmatic pathogen in cystic fibrosis patients

(2008) C. D. Sibley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Microbial Engines That Drive Earth's Biogeochemical Cycles

(2008) P. G. Falkowski et al.   SCIENCE