Dectin-1 Is Required for Resistance to Coccidioidomycosis in Mice

An evolutionary perspective on C-type lectins in infection and immunity

(2012) Linda M. van den Berg et al.   Annals of the New York Academy of Sciences

Factors regulated by interferon gamma and hypoxia-inducible factor 1A contribute to responses that protect mice from Coccidioides immitis infection

(2012) Christopher H Woelk et al.   BMC MICROBIOLOGY

Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis

(2012) Agostinho Carvalho et al.   Cellular & Molecular Immunology

Immunity to fungi

(2012) Salomé LeibundGut-Landmann et al.   CURRENT OPINION IN IMMUNOLOGY

C-type lectin receptors orchestrate antifungal immunity

(2012) Sarah E Hardison et al.   NATURE IMMUNOLOGY

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

(2012) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis

(2012) I. D. Iliev et al.   SCIENCE

Innate Antifungal Immunity: The Key Role of Phagocytes

(2011) Gordon D. Brown   Annual Review of Immunology

The role of reactive oxygen intermediates in experimental coccidioidomycois in mice

(2011) David A Margolis et al.   BMC MICROBIOLOGY

Restoration of Pattern Recognition Receptor Costimulation to Treat Chromoblastomycosis, a Chronic Fungal Infection of the Skin

(2011) Maria da Glória Sousa et al.   Cell Host & Microbe

Targeting Syk-Card9-activating C-type lectin receptors by vaccine adjuvants: Findings, implications and open questions

(2011) Roland Lang et al.   IMMUNOBIOLOGY

Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice

(2011) Marcel Wüthrich et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic Variation in the Dectin-1/CARD9 Recognition Pathway and Susceptibility to Candidemia

(2011) Diana C. Rosentul et al.   JOURNAL OF INFECTIOUS DISEASES

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

Dectin-1: a role in antifungal defense and consequences of genetic polymorphisms in humans

(2010) Mohlopheni J. Marakalala et al.   MAMMALIAN GENOME

Coccidioidomycosis in African Americans

(2010) Barbara E. Ruddy et al.   MAYO CLINIC PROCEEDINGS

Human Dendritic Cells Activated via Dectin-1 Are Efficient at Priming Th17, Cytotoxic CD8 T and B Cell Responses

(2010) Sudhanshu Agrawal et al.   PLoS One

Distinct Roles for Dectin-1 and TLR4 in the Pathogenesis of Aspergillus fumigatus Keratitis

(2010) Sixto M. Leal et al.   PLoS Pathogens

Requisite Role for the Dectin-1  -Glucan Receptor in Pulmonary Defense against Aspergillus fumigatus

(2009) J. L. Werner et al.   JOURNAL OF IMMUNOLOGY

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

Capsule of Cryptococcus neoformans grows by enlargement of polysaccharide molecules

(2009) S. Frases et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages

(2008) Gerben Ferwerda et al.   CELLULAR MICROBIOLOGY

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors

(2008) Kevin M. Dennehy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

DC activated via dectin-1 convert Treg into IL-17 producers

(2008) Fabiola Osorio et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Susceptibility to Coccidioides species in C57BL/6 mice is associated with expression of a truncated splice variant of Dectin-1 (Clec7a)

(2008) M del Pilar Jiménez-A et al.   GENES AND IMMUNITY