Article
Food Science & Technology
Rui Huang, Zhenjun Zhu, Shujian Wu, Juan Wang, Mengfei Chen, Wei Liu, Aohuan Huang, Jumei Zhang, Qingping Wu, Yu Ding
Summary: This study found that polysaccharides from Cordyceps militaris (CMP) can improve obesity symptoms in high-fat diet-fed mice by modulating gut microbes and related metabolites.
FOOD RESEARCH INTERNATIONAL
(2022)
Review
Biochemistry & Molecular Biology
Jamil Ahmad, Imran Khan, Gokhan Zengin, Mohamad Fawzi Mahomoodally
Summary: Obesity is a global public health burden with complex etiology. Different approaches are available to treat and manage obesity, but they have limitations and adverse effects. Gut microbiota is a novel target for obesity treatment. Dietary factors, including diet, prebiotics, and probiotics, may be important for gut microbiota health and obesity management. This review provides an overview of the role of gut microbiota in obesity and the importance of dietary factors.
Article
Food Science & Technology
Xiaolu Zhou, SolJu Pak, Daotong Li, Li Dong, Fang Chen, Xiaosong Hu, Lingjun Ma
Summary: This study found that bamboo shoots have a protective effect against high-fat diet-induced gut dysbiosis, reducing body weight, improving liver damage, insulin resistance, and inflammation in obese mice. Bamboo shoots also increased levels of beneficial bacteria and short-chain fatty acids, while reducing levels of harmful bacteria. These findings suggest that bamboo shoots may be beneficial in treating obesity and its related complications.
Article
Biotechnology & Applied Microbiology
Ata Ur Rehman, Asif Iqbal Khan, Yi Xin, Wang Liang
Summary: Edible mushrooms have been identified as a promising source of functional ingredients and novel functional foods. This study demonstrates the therapeutic effects of Morchella esculenta polysaccharide (MEP) on obesity, colonic inflammation, and gut microbiota dysbiosis. MEP shows potential in attenuating obesity by regulating inflammatory cascades, improving gut microbiome, and modulating gut integrity.
Article
Food Science & Technology
Fei Ren, Chen Meng, Weijun Chen, Haiming Chen, Wenxue Chen
Summary: GAP can regulate the gut microbiota of HFD-mice and effectively prevent weight gain and fat accumulation, improve glucose tolerance, reduce serum and liver lipid concentrations, and inflammation.
Article
Biochemistry & Molecular Biology
Md. Akibul Hasan Bakky, Ngoc Tuan Tran, Ming Zhang, Yongsheng Zhang, Huifen Liang, Yilei Wang, Yueling Zhang, Hongyu Ma, Huaiping Zheng, Shengkang Li
Summary: This study characterized the polysaccharide from Gracilaria lemaneiformis and investigated its fermentation by rabbitfish intestinal microbes. The study found that the polysaccharide was mainly composed of galactose and anhydrogalactose, and it enhanced the production of short-chain fatty acids and altered the gut microbiota. The findings suggest that the polysaccharide has prebiotic potential and could be used as a functional feed additive in aquaculture.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Endocrinology & Metabolism
Jing Song, Qin Liu, Mengqi Hao, Xiaohu Zhai, Juan Chen
Summary: This study assessed the protective effects of the purified neutral polysaccharide PGNP from Platycodon grandiflorum on high-fat diet-induced obesity. PGNP effectively alleviated metabolic syndrome in obese mice, including reductions in body weight, hepatic steatosis, lipid profile, inflammatory response, and insulin resistance. PGNP also positively influenced the gut microbiota and metabolites, increasing species diversity, and reversing the imbalance caused by the high-fat diet.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Yu Yang, Yifan Chang, Yi Wu, Hairong Liu, Qishan Liu, Zuzhe Kang, Man Wu, Hong Yin, Jinyou Duan
Summary: The homogeneous polysaccharide isolated from Lycium barbarum, LBP-W, can significantly alleviate obesity induced by high-fat diet by improving gut microbiota diversity and regulating specific genera, while also increasing the content of short-chain fatty acids (SCFAs).
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Microbiology
Edward C. Deehan, Zhengxiao Zhang, Alessandra Riva, Anissa M. Armet, Maria Elisa Perez-Munoz, Nguyen K. Nguyen, Jacqueline A. Krysa, Benjamin Seethaler, Yuan-Yuan Zhao, Janis Cole, Fuyong Li, Bela Hausmann, Andreas Spittler, Julie-Anne Nazare, Nathalie M. Delzenne, Jonathan M. Curtis, Wendy Wismer, Spencer D. Proctor, Jeffrey A. Bakal, Stephan C. Bischoff, Dan Knights, Catherine J. Field, David Berry, Carla M. Prado, Jens Walter
Summary: This study demonstrates the efficacy of purified dietary fibers when used as supplements and suggests that the satiating effects of AX may be linked to bacterial taxa that ferment the fiber or utilize breakdown products.
Article
Biochemistry & Molecular Biology
Teja Klancic, Isabelle Laforest-Lapointe, Jolene Wong, Ashley Choo, Jodi E. Nettleton, Faye Chleilat, Marie-Claire Arrieta, Raylene A. Reimer
Summary: Pulsed antibiotic treatment early in life increases the risk of obesity, while co-administering prebiotics can reduce fat mass and improve metabolic health. Antibiotic treatment had negative effects on body weight and insulin sensitivity, which were reversed with prebiotic co-administration, especially in a sex-specific manner.
Article
Immunology
Quentin Leyrolle, Renata Cserjesi, Maria D. G. H. Mulders, Giorgia Zamariola, Sophie Hiel, Marco A. Gianfrancesco, Daphne Portheault, Camille Amadieu, Laure B. Bindels, Sophie Leclercq, Julie Rodriguez, Audrey M. Neyrinck, Patrice D. Cani, Nicolas Lanthier, Pierre Trefois, Jerome Bindelle, Nicolas Paquot, Miriam Cnop, Jean-Paul Thissen, Olivier Klein, Olivier Luminet, Nathalie M. Delzenne
Summary: The study showed that inulin intake can help improve mood and cognitive flexibility in obese subjects. Patients with specific microbial signatures were more likely to benefit from prebiotic supplementation. Positive responders to inulin intervention in terms of mood exhibited worse metabolic and inflammatory profiles at baseline.
BRAIN BEHAVIOR AND IMMUNITY
(2021)
Review
Nutrition & Dietetics
Soghra Bagheri, Samaneh Zolghadri, Agata Stanek
Summary: Obesity is linked to metabolic abnormalities, cardiovascular diseases, and cancer. The rate of obesity has increased in recent decades, and there is a connection between obesity and the gut microbiota. Inflammation plays a role in this connection. Anti-inflammatory nutrients, foods, and diets are important in managing obesity.
Article
Food Science & Technology
Haodong Liu, Yan Xing, Yinbo Wang, Xinxiu Ren, Danyang Zhang, Jianying Dai, Zhilong Xiu, Shiqiang Yu, Yuesheng Dong
Summary: This study found that Dendrobium officinale polysaccharide (DOP) can reduce the risk of developing type 2 diabetes mellitus (T2DM) by regulating gut microbiota, relieving inflammation, and improving insulin resistance.
Article
Nutrition & Dietetics
Piyarat Oraphruek, Charoonsri Chusak, Sathaporn Ngamukote, Vorthon Sawaswong, Prangwalai Chanchaem, Sunchai Payungporn, Tanyawan Suantawee, Sirichai Adisakwattana
Summary: This study aimed to evaluate the effects of a multispecies probiotics mixed with fructooligosaccharides on body composition, antioxidant status, and gut microbiome composition in overweight and obese individuals. The results showed that synbiotic supplementation led to a significant reduction in waist circumference and body fat percentage, as well as improvements in antioxidant capacity and gut microbiota composition. Therefore, multispecies synbiotic supplementation could be a beneficial strategy for improving body composition, antioxidant status, and gut microbiome composition in overweight and obese subjects.
Article
Microbiology
Gang He, Tangcong Chen, Lifen Huang, Yiyuan Zhang, Yanjiao Feng, Shaokui Qu, Xiaojing Yin, Li Liang, Jun Yan, Wei Liu
Summary: This study found that Tremella fuciformis polysaccharide (TP) can inhibit high-fat diet-induced obesity by modulating inflammation and the microbe-gut-brain axis, improving gut microbiota disorders and reducing fat accumulation and abnormal blood glucose and lipid levels.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Yufeng Chen, Zhenlei Zhao, Guobin Xia, Fan Xue, Chun Chen, Ying Zhang
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Food Science & Technology
Yufeng Chen, Guobin Xia, Zhenlei Zhao, Fan Xue, Yanpei Gu, Chun Chen, Ying Zhang
JOURNAL OF FUNCTIONAL FOODS
(2020)
Article
Chemistry, Medicinal
Xing-Wei Xiang, Rui Wang, Li-Wen Yao, Yu-Fang Zhou, Pei-Long Sun, Bin Zheng, Yu-Feng Chen
Summary: MP demonstrates promising effects in anti-inflammatory responses and protection against ulcerative colitis in mice, while also regulating the richness and diversity of intestinal microbial communities.
Article
Biotechnology & Applied Microbiology
Yueqi Wang, Yanyan Wu, Yingying Shen, Chunsheng Li, Yongqiang Zhao, Bo Qi, Laihao Li, Yufeng Chen
Summary: This study successfully established a volatile fingerprint of fermented mandarin fish using electronic nose and gas chromatography-ion mobility spectrometry analysis, allowing for differentiation of mandarin fish samples at different fermentation stages. Additionally, by identifying 43 volatile organic compounds and performing partial least squares discrimination analysis, three potential biomarkers for fermentation were identified, providing a theoretical basis for real-time monitoring of flavor and quality control in traditional mandarin fish fermentation.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Food Science & Technology
Yufeng Chen, Jingchong Peng, Yueqi Wang, Daniel Wadhawan, Lijun Wu, Xiaojing Gao, Yi Sun, Guobin Xia
Summary: This study found that the type of polysaccharide significantly affected the performance of nanoparticles, with CMC/S/Z showing better stability and ALG/S/Z exhibiting higher bioaccessibility.
Article
Nutrition & Dietetics
Xingwei Xiang, Qihong Jiang, Wan Shao, Jinhong Li, Yufang Zhou, Lin Chen, Shanggui Deng, Bin Zheng, Yufeng Chen
Summary: The study demonstrated the anti-inflammatory effects of shrimp peptide on a DSS-induced mouse model of UC, showing improvements in colitis severity, intestinal barrier integrity, inflammatory cytokines, antioxidant indices, and intestinal flora balance. These findings suggest that shrimp peptide has prophylactic and therapeutic effects on UC, indicating its broad medicinal applications.
FRONTIERS IN NUTRITION
(2021)
Article
Nutrition & Dietetics
Yufeng Chen, Xiaojing Gao, Shucheng Liu, Qiuxing Cai, Lijun Wu, Yi Sun, Guobin Xia, Yueqi Wang
Summary: In this study, glycosylated lactoferrin was successfully used to establish stable zein/glycosylated lactoferrin nanoparticles for encapsulating 7,8-dihydroxyflavone. The encapsulated 7,8-dihydroxyflavone exhibited an amorphous state inside the nanoparticles and showed good water redispersibility and bioaccessibility. This research provides a theoretical reference for the application of zein-based delivery systems.
FRONTIERS IN NUTRITION
(2022)
Article
Food Science & Technology
Xing-Wei Xiang, Rui Wang, Hui Chen, Yu-Feng Chen, Guo-Xin Shen, Shu-Lai Liu, Pei-Long Sun, Lin Chen
Summary: A new water-soluble polysaccharide was extracted and purified from mussels, and its structure and cellular antioxidant levels were studied. The polysaccharide was mainly composed of glucose and showed characteristic polysaccharide bands. Moreover, it was found that the polysaccharide could protect cells from oxidative stress by increasing antioxidant enzyme activities and reducing oxidative damage markers.
Review
Food Science & Technology
Yufeng Chen, Yi Sun, Yuting Ding, Yicheng Ding, Shulai Liu, Xuxia Zhou, Huawei Wu, Jianbo Xiao, Baiyi Lu
Summary: Fish oil, rich in long-chain omega-3 PUFAs, is widely used in fortified foods for its health benefits. However, its oxidation sensitivity, poor water solubility, and fishy off-flavor hinder its use in the food industry. In the past two decades, progress has been made in constructing fish oil emulsions to improve its physicochemical and functional properties. This review focuses on the strategies, stabilization mechanisms, and applications of fish oil emulsions, as well as the role of stabilizers in their stability. It also discusses the use of fish oil emulsions in the food industry and nutrition field and highlights possible innovative trends and applications.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Chemistry, Applied
Yufeng Chen, Yi Sun, Yueli Meng, Shulai Liu, Yicheng Ding, Xuxia Zhou, Yuting Ding
Summary: In this study, dynamic high-pressure microfluidization technology combined with TGase cross-linking was used to prepare DHPM-TG-WPC, and the thermal stabilization mechanism of nano-emulsions prepared with DHPM-TG-WPC was explored. Results showed that DHPM treatment could promote the formation of TG-crosslinked WPC polymers and improve the stability of nanoemulsions.
Article
Food Science & Technology
Yufeng Chen, Xiaojing Gao, Weiming Su, Xuxia Zhou, Yicheng Ding, Shulai Liu, Yuting Ding
Summary: In this study, gelatin-based emulsion-filled gels (EFGs) with high thermal stability and gel strength were prepared by cross-linking with transglutaminase (TG). The impact of varying cross-linking time on the thermal stability and gel strength of EFGs was explored. The results showed that enzymatic cross-linking increased gel strength and thermal denaturation temperature, and affected the structural changes of EFGs.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Review
Agriculture, Multidisciplinary
Yufeng Chen, Hao Lu, Yicheng Ding, Shulai Liu, Yuting Ding, Baiyi Lu, Jianbo Xiao, Xuxia Zhou
Summary: Fucoxanthin has preventive and therapeutic effects on neurological disorders by acting on multiple targets, such as regulating apoptosis, reducing oxidative stress, activating autophagy pathway, inhibiting protein aggregation, improving dopamine secretion, attenuating neuroinflammation, etc. Further research is needed to explore the metabolism and transport of fucoxanthin through the gut-brain process. Dietary supplementation of fucoxanthin is also suggested for prevention of neurological disorders.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Food Science & Technology
Xingwei Xiang, Rui Wang, Lin Chen, Yufeng Chen, Bin Zheng, Shanggui Deng, Shulai Liu, Peilong Sun, Guoxin Shen
Summary: This study investigated the protective effect of mussel polysaccharide (MP) on cyclophosphamide-induced intestinal mucosal immunosuppression and microbial dysbiosis in mice. The results showed that MP can stimulate cytokine secretion and transcription factor production, activate the NF-kappa B pathway, and improve short-chain fatty acid levels. In addition, MP can modulate gut microbiota composition, increasing the abundance of probiotics and reducing the proportion of pathogenic species. These findings suggest that MP has potential immunomodulatory activity and can improve gut health.
NPJ SCIENCE OF FOOD
(2022)
Article
Biochemistry & Molecular Biology
Yufeng Chen, Guobin Xia, Zhenlei Zhao, Fan Xue, Chun Chen, Ying Zhang
Article
Biochemistry & Molecular Biology
Yufeng Chen, Fan Xue, Guobin Xia, Zhenlei Zhao, Chun Chen, Yunhong Li, Ying Zhang
