Identification of a potent salicylic acid-based inhibitor of tyrosine phosphatase PTP1B

Discovery of novel and potent heterocyclic carboxylic acid derivatives as protein tyrosine phosphatase 1B inhibitors

(2012) Sujay Basu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties

(2012) Dayong Shi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control

(2011) Doina Popov   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors

(2011) Yantao He et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain

(2011) Brent D.G. Page et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antagonism of the Stat3-Stat3 Protein Dimer with Salicylic Acid Based Small Molecules

(2011) Steven Fletcher et al.   ChemMedChem

Toxicological Disruption of Signaling Homeostasis: Tyrosine Phosphatases as Targets

(2010) James M. Samet et al.   Annual Review of Pharmacology and Toxicology

Protein tyrosine phosphatases as drug targets: strategies and challenges of inhibitor development

(2010) Alastair J Barr   Future Medicinal Chemistry

Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents

(2010) B. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTP1B: a double agent in metabolism and oncogenesis

(2010) Shu-Chin Yip et al.   TRENDS IN BIOCHEMICAL SCIENCES

Disruption of Transcriptionally Active Stat3 Dimers with Non-phosphorylated, Salicylic Acid-Based Small Molecules: Potent in vitro and Tumor Cell Activities

(2009) Steven Fletcher et al.   CHEMBIOCHEM

The therapeutic potential of phosphatase inhibitors

(2009) Viktor V Vintonyak et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Real-time xCELLigence impedance analysis of the cytotoxicity of dental composite components on human gingival fibroblasts

(2009) Ebru Urcan et al.   DENTAL MATERIALS

Recent Advances in the Discovery of Competitive Protein Tyrosine Phosphatase 1B Inhibitors for the Treatment of Diabetes, Obesity, and Cancer

(2009) Andrew P. Combs   JOURNAL OF MEDICINAL CHEMISTRY