- Home
- Publications
- Publication Search
- Publication Details
Title
Impact of ion class and time on oral drug molecular properties
Authors
Keywords
-
Journal
MedChemComm
Volume 2, Issue 2, Pages 91-105
Publisher
Royal Society of Chemistry (RSC)
Online
2010-11-11
DOI
10.1039/c0md00157k
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Factors Determining the Selection of Organic Reactions by Medicinal Chemists and the Use of These Reactions in Arrays (Small Focused Libraries)
- (2010) Tony W. J. Cooper et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Using an in vitro cytotoxicity assay to aid in compound selection for in vivo safety studies
- (2010) Nigel Greene et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Getting physical in drug discovery: a contemporary perspective on solubility and hydrophobicity
- (2010) Alan P. Hill et al. DRUG DISCOVERY TODAY
- Lipophilicity in drug discovery
- (2010) Michael J Waring Expert Opinion on Drug Discovery
- An Analysis of the Binding Efficiencies of Drugs and Their Leads in Successful Drug Discovery Programs
- (2010) Emanuele Perola JOURNAL OF MEDICINAL CHEMISTRY
- Physicochemical Space for Optimum Oral Bioavailability: Contribution of Human Intestinal Absorption and First-Pass Elimination
- (2010) Manthena V. S. Varma et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cheminformatic Tools for Medicinal Chemists
- (2010) Steven W. Muchmore et al. JOURNAL OF MEDICINAL CHEMISTRY
- The β-d-Glucose Scaffold as a β-Turn Mimetic
- (2009) Ralph F. Hirschmann et al. ACCOUNTS OF CHEMICAL RESEARCH
- Synthesis of Natural Product Inspired Compound Collections
- (2009) Kamal Kumar et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Physicochemical property profiles of marketed drugs, clinical candidates and bioactive compounds
- (2009) Christian Tyrchan et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Using the Golden Triangle to optimize clearance and oral absorption
- (2009) Ted W. Johnson et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Defining optimum lipophilicity and molecular weight ranges for drug candidates—Molecular weight dependent lower logD limits based on permeability
- (2009) Michael J. Waring BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Pharmacological Promiscuity: Dependence on Compound Properties and Target Specificity in a Set of Recent Roche Compounds
- (2009) Jens-Uwe Peters et al. ChemMedChem
- In Silico hERG Modeling: Challenges and Progress
- (2009) David Diller Current Computer-Aided Drug Design
- Medicinal Chemistry Strategies to Minimize Phospholipidosis
- (2009) Andrew Ratcliffe CURRENT MEDICINAL CHEMISTRY
- The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?
- (2009) Timothy J. Ritchie et al. DRUG DISCOVERY TODAY
- Physicochemical drug properties associated within vivotoxicological outcomes: a review
- (2009) David A Price et al. Expert Opinion on Drug Metabolism & Toxicology
- New Developments in Hydrogen Bonding Acidity and Basicity of Small Organic Molecules for the Prediction of Physical and ADMET Properties. Part 2. The Universal Solvation Equation
- (2009) Polina V. Oliferenko et al. Journal of Chemical Information and Modeling
- Do Biologically Relevant Compounds Have More Chance To Be Drugs?
- (2009) De-Xin Kong et al. Journal of Chemical Information and Modeling
- In Silico Prediction of Volume of Distribution in Human Using Linear and Nonlinear Models on a 669 Compound Data Set
- (2009) Giuliano Berellini et al. JOURNAL OF MEDICINAL CHEMISTRY
- Physicochemical Determinants of Human Renal Clearance
- (2009) Manthena V. S. Varma et al. JOURNAL OF MEDICINAL CHEMISTRY
- Novel Chemical Space Exploration via Natural Products
- (2009) Josefin Rosén et al. JOURNAL OF MEDICINAL CHEMISTRY
- Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
- (2009) Frank Lovering et al. JOURNAL OF MEDICINAL CHEMISTRY
- Lessons from 60 years of pharmaceutical innovation
- (2009) Bernard Munos NATURE REVIEWS DRUG DISCOVERY
- The influence of lead discovery strategies on the properties of drug candidates
- (2009) György M. Keserü et al. NATURE REVIEWS DRUG DISCOVERY
- The acid–base profile of a contemporary set of drugs: implications for drug discovery
- (2009) D.T. Manallack SAR AND QSAR IN ENVIRONMENTAL RESEARCH
- Physiochemical drug properties associated with in vivo toxicological outcomes
- (2008) Jason D. Hughes et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Straightforward Recursive Partitioning Model for Discarding Insoluble Compounds in the Drug Discovery Process
- (2008) Claudia Lamanna et al. JOURNAL OF MEDICINAL CHEMISTRY
- Generation of a Set of Simple, Interpretable ADMET Rules of Thumb
- (2008) M. Paul Gleeson JOURNAL OF MEDICINAL CHEMISTRY
- Safety and secondary pharmacology: Successes, threats, challenges and opportunities
- (2008) Jean-Pierre Valentin et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search