Potential atypical antipsychotics: synthesis, binding affinity and SAR of new heterocyclic bioisosteric butyrophenone analogues as multitarget ligands

The role of serotonin receptors in the action of atypical antipsychotic drugs

(2011) HY Meltzer et al.   CURRENT OPINION IN PHARMACOLOGY

Searching for multi-target antipsychotics: Discovery of orally active heterocyclic N-phenylpiperazine ligands of D2-like and 5-HT1A receptors

(2010) Gilda Neves et al.   BIOORGANIC & MEDICINAL CHEMISTRY

5-HT6 Receptor Antagonists as Potential Therapeutics for Cognitive Impairment

(2010) Gerard Rosse et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Discovery of Bishomo(hetero)arylpiperazines as Novel Multifunctional Ligands Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors

(2010) Stefania Butini et al.   JOURNAL OF MEDICINAL CHEMISTRY

The effectiveness of multi-target agents in schizophrenia and mood disorders: Relevance of receptor signature to clinical action

(2010) Erik H.F. Wong et al.   PHARMACOLOGY & THERAPEUTICS

No genetic association between dopamine D1 receptor gene and [early onset] schizophrenia

(2010) Chen Zhang et al.   PSYCHIATRY RESEARCH

Designing Multiple Ligands – Medicinal Chemistry Strategies and Challenges

(2009) Richard Morphy et al.   CURRENT PHARMACEUTICAL DESIGN

5-HT6antagonists as potential treatment for cognitive dysfunction

(2009) Kevin G. Liu et al.   DRUG DEVELOPMENT RESEARCH

Does stimulation of 5-HT1A receptors improve cognition in schizophrenia?

(2008) Herbert Y. Meltzer et al.   BEHAVIOURAL BRAIN RESEARCH

Synthesis, Binding Affinity, and Molecular Docking Analysis of New Benzofuranone Derivatives as Potential Antipsychotics

(2008) Reyes Aranda et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of a New Class of Potential Multifunctional Atypical Antipsychotic Agents Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors: Design, Synthesis, and Effects on Behavior

(2008) Stefania Butini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors

(2008) V.J. Aloyo et al.   PHARMACOLOGY & THERAPEUTICS