Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 53, Issue 12, Pages 4803-4807Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jm100294b
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Funding
- MIUR-Rome, Italy
- NeuroSearch A/S Ballerup, Denmark
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As a continuation of our efforts to develop innovative ligands for D-3, 5-HT1A, and 5-HT2A receptors with low propensity to block hERG channels, we propose a series bishetero(homo)arylpiperazines 5a-m as novel and potent multifunctional ligands characterized by low occupancy at D-2 and 5-HT2C receptors.
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