Increased BBB Permeability Enhances Activation of Microglia and Exacerbates Loss of Dendritic Spines After Transient Global Cerebral Ischemia

Reversible recovery of neuronal structures depends on the degree of neuronal damage after global cerebral ischemia in mice

(2017) Lirui Zhu et al.   EXPERIMENTAL NEUROLOGY

Sac-1004, a vascular leakage blocker, reduces cerebral ischemia—reperfusion injury by suppressing blood–brain barrier disruption and inflammation

(2017) Haiying Zhang et al.   Journal of Neuroinflammation

Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift

(2017) Yasir N. Jassam et al.   NEURON

An altered blood–brain barrier contributes to brain iron accumulation and neuroinflammation in the 6-OHDA rat model of Parkinson’s disease

(2017) Sonia Olmedo-Díaz et al.   NEUROSCIENCE

Normobaric Hyperoxia Reduces Blood Occludin Fragments in Rats and Patients With Acute Ischemic Stroke

(2017) Shuhai Shi et al.   STROKE

Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology

(2016) Adrian Olmos-Alonso et al.   BRAIN

Impairment of blood brain barrier is related with the neuroinflammation induced peripheral immune status in intracerebroventricular colchicine injected rats: An experimental study with mannitol

(2016) Susmita Sil et al.   BRAIN RESEARCH

Early Activation of Experience-Independent Dendritic Spine Turnover in a Mouse Model of Alzheimer's Disease

(2016) Jacqueline K. Heiss et al.   CEREBRAL CORTEX

Transient global cerebral ischemia induces rapid and sustained reorganization of synaptic structures

(2016) Lirui Zhu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Salicylic acid analogues as chemical exchange saturation transfer MRI contrast agents for the assessment of brain perfusion territory and blood–brain barrier opening after intra-arterial infusion

(2016) Xiaolei Song et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

MiR-126 Contributes to Human Umbilical Cord Blood Cell-Induced Neurorestorative Effects After Stroke in Type-2 Diabetic Mice

(2016) Jieli Chen et al.   STEM CELLS

Regulation of Caveolin-1 Expression Determines Early Brain Edema After Experimental Focal Cerebral Ischemia

(2016) Kang-Ho Choi et al.   STROKE

Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

(2016) Yejie Shi et al.   Nature Communications

Repeated Exposure to Ketamine–Xylazine during Early Development Impairs Motor Learning–dependent Dendritic Spine Plasticity in Adulthood

(2015) Lianyan Huang et al.   ANESTHESIOLOGY

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Ultrastructural analysis of blood–brain barrier breakdown in the peri-infarct zone in young adult and aged mice

(2015) Patrick C Nahirney et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Delayed Inhibition of VEGF Signaling after Stroke Attenuates Blood-Brain Barrier Breakdown and Improves Functional Recovery in a Comorbidity-Dependent Manner

(2015) P. Reeson et al.   JOURNAL OF NEUROSCIENCE

Biochemical Computation for Spine Structural Plasticity

(2015) Jun Nishiyama et al.   NEURON

Re-evaluation of the Blood-Brain Barrier in the Presence of Alzheimer’s Disease Pathology

(2015) Jason D. Ulrich et al.   NEURON

Mannitol and Outcome in Intracerebral Hemorrhage

(2015) Xia Wang et al.   STROKE

Double function at the blood–brain barrier

(2014) Christer Betsholtz   NATURE

Sleep promotes branch-specific formation of dendritic spines after learning

(2014) G. Yang et al.   SCIENCE

A New Micro–Computed Tomography–Based High-Resolution Blood–Brain Barrier Imaging Technique to Study Ischemic Stroke

(2014) Jin-Yong Park et al.   STROKE

Classical activation of microglia in CD200-deficient mice is a consequence of blood brain barrier permeability and infiltration of peripheral cells

(2013) Stephanie Denieffe et al.   BRAIN BEHAVIOR AND IMMUNITY

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion

(2013) Helena W Morrison et al.   Journal of Neuroinflammation

A Dramatic Increase of C1q Protein in the CNS during Normal Aging

(2013) A. H. Stephan et al.   JOURNAL OF NEUROSCIENCE

Microglia: New Roles for the Synaptic Stripper

(2013) Helmut Kettenmann et al.   NEURON

Peripheral elevation of TNF-  leads to early synaptic abnormalities in the mouse somatosensory cortex in experimental autoimmune encephalomyelitis

(2013) G. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vasculogenesis in Experimental Stroke After Human Cerebral Endothelial Cell Transplantation

(2013) Hiroto Ishikawa et al.   STROKE

The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease

(2012) Alexander H. Stephan et al.   Annual Review of Neuroscience

Permeating the Blood Brain Barrier and Abrogating the Inflammation in Stroke: Implications for Stroke Therapy

(2012) Cesar V. Borlongan et al.   CURRENT PHARMACEUTICAL DESIGN

Capillary blood flow around microglial somata determines dynamics of microglial processes in ischemic conditions

(2011) Tadashi Masuda et al.   GLIA

Comparative Effects of Glucose- and Mannitol-Induced Osmolar Stress on Blood—Brain Barrier Function in Ovine Fetuses and Lambs

(2011) Barbara S Stonestreet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Maturation of a Recurrent Excitatory Neocortical Circuit by Experience-Dependent Unsilencing of Newly Formed Dendritic Spines

(2011) Michael C. Ashby et al.   NEURON

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Inconsistent blood brain barrier disruption by intraarterial mannitol in rabbits: implications for chemotherapy

(2010) Shailendra Joshi et al.   JOURNAL OF NEURO-ONCOLOGY

Thinned-skull cranial window technique for long-term imaging of the cortex in live mice

(2010) Guang Yang et al.   Nature Protocols

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Dendritic Spine Dynamics

(2009) D. Harshad Bhatt et al.   Annual Review of Physiology

A potential role for pro-inflammatory cytokines in regulating synaptic plasticity in major depressive disorder

(2009) Rushaniya A. Khairova et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Inflammation Triggers Synaptic Alteration and Degeneration in Experimental Autoimmune Encephalomyelitis

(2009) D. Centonze et al.   JOURNAL OF NEUROSCIENCE

Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals

(2009) H. Wake et al.   JOURNAL OF NEUROSCIENCE

Stably maintained dendritic spines are associated with lifelong memories

(2009) Guang Yang et al.   NATURE

Plasticity during stroke recovery: from synapse to behaviour

(2009) Timothy H. Murphy et al.   NATURE REVIEWS NEUROSCIENCE

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

(2009) Mathias Gelderblom et al.   STROKE

Dynamic Changes in Vascular Permeability, Cerebral Blood Volume, Vascular Density, and Size after Transient Focal Cerebral Ischemia in Rats: Evaluation with Contrast-Enhanced Magnetic Resonance Imaging

(2008) Chien-Yuan Lin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON