Strategies to increase the activity of microglia as efficient protectors of the brain against infections

Additive Microglia-Mediated Neuronal Injury Caused by Amyloid-β and Bacterial TLR Agonists in Murine Neuron-Microglia Co-Cultures Quantified by an Automated Image Analysis using Cognition Network Technology

(2018) Sandra Schütze et al.   JOURNAL OF ALZHEIMERS DISEASE

Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection

(2014) Sandra Ribes et al.   Journal of Neuroinflammation

Identifying the Cellular Targets of Drug Action in the Central Nervous System Following Corticosteroid Therapy

(2013) Stuart I. Jenkins et al.   ACS Chemical Neuroscience

The human JC polyomavirus (JCPyV): virological background and clinical implications

(2013) Hans H. Hirsch et al.   APMIS

Attenuation of cognitive impairment by the nonbacteriolytic antibiotic daptomycin in Wistar rats submitted to pneumococcal meningitis

(2013) Tatiana Barichello et al.   BMC NEUROSCIENCE

Anti-inflammatory substances can influence some glial cell types but not others

(2013) Johan Forshammar et al.   BRAIN RESEARCH

New Insights on Human Polyomavirus JC and Pathogenesis of Progressive Multifocal Leukoencephalopathy

(2013) Anna Bellizzi et al.   Clinical & Developmental Immunology

Palmitoylethanolamide in Homeostatic and Traumatic Central Nervous System Injuries

(2013) Emanuela Esposito et al.   CNS & Neurological Disorders-Drug Targets

Dimethyl Fumarate Modulation of Immune and Antioxidant Responses: Application to HIV Therapy

(2013) Alexander J. Gill et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Bacterial meningitis: new therapeutic approaches

(2013) Roland Nau et al.   Expert Review of Anti-Infective Therapy

Microglial activation and expression of immune-related genes in a ratex vivonervous system model after infection withListeria monocytogenes

(2013) Sara Remuzgo-MartÍnez et al.   GLIA

Resistance of the Brain to Escherichia coli K1 Infection Depends on MyD88 Signaling and the Contribution of Neutrophils and Monocytes

(2013) Sandra Ribes et al.   INFECTION AND IMMUNITY

Fingolimod phosphate promotes the neuroprotective effects of microglia

(2013) Hiromi Noda et al.   JOURNAL OF NEUROIMMUNOLOGY

MyD88 is crucial for the development of a protective CNS immune response to Toxoplasma gondii infection

(2013) Marbel Torres et al.   Journal of Neuroinflammation

Toll-like receptor stimulation increases phagocytosis of Cryptococcus neoformans by microglial cells

(2013) Sandra Redlich et al.   Journal of Neuroinflammation

Interactions between Blood-Borne Streptococcus pneumoniae and the Blood-Brain Barrier Preceding Meningitis

(2013) Federico Iovino et al.   PLoS One

Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology

(2013) J.-P. Michaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional diversity of microglia – how heterogeneous are they to begin with?

(2013) Uwe-Karsten Hanisch   Frontiers in Cellular Neuroscience

Genetic deletion of CD36 enhances injury after acute neonatal stroke

(2012) Moon-Sook Woo et al.   ANNALS OF NEUROLOGY

Adjunctive Daptomycin Attenuates Brain Damage and Hearing Loss More Efficiently than Rifampin in Infant Rat Pneumococcal Meningitis

(2012) Denis Grandgirard et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Role of Microglial Cell Subsets in Alzheimers Disease

(2012) G. Naert et al.   Current Alzheimer Research

Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia

(2012) Jörg Scheffel et al.   GLIA

IbeA and OmpA of Escherichia coli K1 Exploit Rac1 Activation for Invasion of Human Brain Microvascular Endothelial Cells

(2012) Ravi Maruvada et al.   INFECTION AND IMMUNITY

Inflammasome-Dependent IFN-  Drives Pathogenesis in Streptococcus pneumoniae Meningitis

(2012) A. J. Mitchell et al.   JOURNAL OF IMMUNOLOGY

The nucleotide-binding oligomerization domain-containing-2 ligand muramyl dipeptide enhances phagocytosis and intracellular killing of Escherichia coli K1 by Toll-like receptor agonists in microglial cells

(2012) Sandra Ribes et al.   JOURNAL OF NEUROIMMUNOLOGY

Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 and Streptococcus pneumoniae R6 by microglial cells

(2012) Sandra Redlich et al.   JOURNAL OF NEUROIMMUNOLOGY

Glatiramer Acetate Increases Phagocytic Activity of Human Monocytes In Vitro and in Multiple Sclerosis Patients

(2012) Refik Pul et al.   PLoS One

Frequency and Large T (LT) Sequence of JC Polyomavirus DNA in Oligodendrocytes, Astrocytes and Granular Cells in Non-PML Brain

(2011) Julianne Bayliss et al.   BRAIN PATHOLOGY

Pathogenesis and Pathophysiology of Pneumococcal Meningitis

(2011) B. B. Mook-Kanamori et al.   CLINICAL MICROBIOLOGY REVIEWS

Virus reactivation: a panoramic view in human infections

(2011) Christopher M Traylen et al.   Future Virology

Mitoxantrone exerts both cytotoxic and immunoregulatory effects on activated microglial cells

(2011) Jun-Min Li et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Dimethyl Fumarate, an Immune Modulator and Inducer of the Antioxidant Response, Suppresses HIV Replication and Macrophage-Mediated Neurotoxicity: A Novel Candidate for HIV Neuroprotection

(2011) Stephanie A. Cross et al.   JOURNAL OF IMMUNOLOGY

The Toll-Like Receptor 3-Mediated Antiviral Response Is Important for Protection against Poliovirus Infection in Poliovirus Receptor Transgenic Mice

(2011) Y. Abe et al.   JOURNAL OF VIROLOGY

Immunosuppression increases latent infection of brain by JC polyomavirus

(2011) Julianne Bayliss et al.   PATHOLOGY

Purinergic Signaling Induces Cyclooxygenase-1-Dependent Prostanoid Synthesis in Microglia: Roles in the Outcome of Excitotoxic Brain Injury

(2011) Josef Anrather et al.   PLoS One

CD14 and TRIF govern distinct responsiveness and responses in mouse microglial TLR4 challenges by structural variants of LPS

(2010) Tommy Regen et al.   BRAIN BEHAVIOR AND IMMUNITY

Therapy Failure following Selection of Enfuvirtide‐Resistant HIV‐1 in Cerebrospinal Fluid

(2010) S. F. L. van Lelyveld et al.   CLINICAL INFECTIOUS DISEASES

Penetration of Drugs through the Blood-Cerebrospinal Fluid/Blood-Brain Barrier for Treatment of Central Nervous System Infections

(2010) R. Nau et al.   CLINICAL MICROBIOLOGY REVIEWS

Glatiramer Acetate Modulates TNF-α and IL-10 Secretion in Microglia and Promotes Their Phagocytic Activity

(2010) Refik Pul et al.   Journal of Neuroimmune Pharmacology

Bacteremia in a Multilevel Geriatric Hospital

(2010) Emily Lubart et al.   Journal of the American Medical Directors Association

Understanding mechanisms and the role of differentiation in pathogenesis of Toxoplasma gondii: a review

(2010) William J Sullivan Jr et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

The viral TLR3 agonist poly(I:C) stimulates phagocytosis and intracellular killing of Escherichia coli by microglial cells

(2010) Sandra Ribes et al.   NEUROSCIENCE LETTERS

Neonatal Bacterial Meningitis

(2010) Jean Gaschignard et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Short-term rifampicin pretreatment reduces inflammation and neuronal cell death in a rabbit model of bacterial meningitis*

(2009) Annette Spreer et al.   CRITICAL CARE MEDICINE

Toll-Like Receptor Stimulation Enhances Phagocytosis and Intracellular Killing of Nonencapsulated and Encapsulated Streptococcus pneumoniae by Murine Microglia

(2009) S. Ribes et al.   INFECTION AND IMMUNITY

British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children

(2009) Guy Thwaites et al.   JOURNAL OF INFECTION

Community-Acquired Bacterial Meningitis in Elderly Patients

(2009) Carmen Cabellos et al.   MEDICINE

Monocyte-Mediated Defense Against Microbial Pathogens

(2008) Natalya V. Serbina et al.   Annual Review of Immunology

Validation of the CNS Penetration-Effectiveness Rank for Quantifying Antiretroviral Penetration Into the Central Nervous System

(2008) Scott Letendre   ARCHIVES OF NEUROLOGY

Polar bacterial invasion and translocation ofStreptococcus suisacross the blood-cerebrospinal fluid barrierin vitro

(2008) Tobias Tenenbaum et al.   CELLULAR MICROBIOLOGY

Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide

(2008) Frida Loría et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Toll-Like Receptor Prestimulation Increases Phagocytosis of Escherichia coli DH5  and Escherichia coli K1 Strains by Murine Microglial Cells

(2008) S. Ribes et al.   INFECTION AND IMMUNITY

Protective autoimmunity in the nervous system

(2008) Jerome J. Graber et al.   PHARMACOLOGY & THERAPEUTICS

The orphan receptor GPR55 is a novel cannabinoid receptor

(2007) E Ryberg et al.   BRITISH JOURNAL OF PHARMACOLOGY

Community-acquired bacterial meningitis in cirrhotic patients

(2007) C. Cabellos et al.   CLINICAL MICROBIOLOGY AND INFECTION

Microglia produce and hydrolyze palmitoylethanolamide

(2007) Giulio G. Muccioli et al.   NEUROPHARMACOLOGY