Selenadiazole derivatives as theranostic agents for simultaneous cancer chemo-/radiotherapy by targeting thioredoxin reductase

Dual-function nanosystem for synergetic cancer chemo-/radiotherapy through ROS-mediated signaling pathways

(2015) Lizhen He et al.   BIOMATERIALS

Rational Design of Selenadiazole Derivatives to Antagonize Hyperglycemia-Induced Drug Resistance in Cancer Cells

(2015) Yuedan Liu et al.   Chemistry-An Asian Journal

Synthesis of selenazolopyridine derivatives with capability to induce apoptosis in human breast carcinoma MCF-7 cells through scavenge of intracellular ROS

(2015) Meiyun Zhou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, and biological evaluation of benzoselenazole-stilbene hybrids as multi-target-directed anti-cancer agents

(2015) Jun Yan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Selenium-Containing Chrysin and Quercetin Derivatives: Attractive Scaffolds for Cancer Therapy

(2015) Inês L. Martins et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Xanthohumol Analogues and Discovery of Potent Thioredoxin Reductase Inhibitor as Potential Anticancer Agent

(2015) Baoxin Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design of an intelligent sub-50 nm nuclear-targeting nanotheranostic system for imaging guided intranuclear radiosensitization

(2015) Wenpei Fan et al.   Chemical Science

Rational design and fabrication of a cancer-targeted chitosan nanocarrier to enhance selective cellular uptake and anticancer efficacy of selenocystine

(2015) Bo Yu et al.   Journal of Materials Chemistry B

New application of fluorescent organotin compounds derived from Schiff bases: synthesis, X-ray structures, photophysical properties, cytotoxicity and fluorescent bioimaging

(2015) Víctor M. Jiménez-Pérez et al.   Journal of Materials Chemistry B

Smart Human Serum Albumin-Indocyanine Green Nanoparticles Generated by Programmed Assembly for Dual-Modal Imaging-Guided Cancer Synergistic Phototherapy

(2014) Zonghai Sheng et al.   ACS Nano

Activatable Hyaluronic Acid Nanoparticle as a Theranostic Agent for Optical/Photoacoustic Image-Guided Photothermal Therapy

(2014) Liwen Zhang et al.   ACS Nano

A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo

(2014) Taotao Zou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Activatable Theranostic for Targeted Cancer Therapy and Imaging

(2014) Sankarprasad Bhuniya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sensitization of cancer cells to radiation by selenadiazole derivatives by regulation of ROS-mediated DNA damage and ERK and AKT pathways

(2014) Qiang Xie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cyclometalated Ir(iii) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy

(2014) Rui-Rong Ye et al.   CHEMICAL COMMUNICATIONS

Nanomaterials for Theranostics: Recent Advances and Future Challenges

(2014) Eun-Kyung Lim et al.   CHEMICAL REVIEWS

Selenadiazole derivatives as potent thioredoxin reductase inhibitors that enhance the radiosensitivity of cancer cells

(2014) Yuan-Wei Liang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Targeted Theranostic Platinum(IV) Prodrug with a Built-In Aggregation-Induced Emission Light-Up Apoptosis Sensor for Noninvasive Early Evaluation of Its Therapeutic Responses in Situ

(2014) Youyong Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Glycol Chitosan-Based Fluorescent Theranostic Nanoagents for Cancer Therapy

(2014) Jin-Kyu Rhee et al.   Marine Drugs

Updates on clinical studies of selenium supplementation in radiotherapy

(2014) Irma M Puspitasari et al.   Radiation Oncology

Enhancement of auranofin-induced lung cancer cell apoptosis by selenocystine, a natural inhibitor of TrxR1 in vitro and in vivo

(2014) C Fan et al.   Cell Death & Disease

Selenium substitution endows cystine with radiosensitization activity against cervical cancer cells

(2014) Qiang Xie et al.   RSC Advances

Mesoporous Magnetic Gold “Nanoclusters” as Theranostic Carrier for Chemo-Photothermal Co-therapy of Breast Cancer

(2014) JinRong Peng et al.   Theranostics

Gold Nanoshelled Liquid Perfluorocarbon Magnetic Nanocapsules: a Nanotheranostic Platform for Bimodal Ultrasound/Magnetic Resonance Imaging Guided Photothermal Tumor Ablation

(2014) Hengte Ke et al.   Theranostics

Theranostic Self-Assembly Structure of Gold Nanoparticles for NIR Photothermal Therapy and X-Ray Computed Tomography Imaging

(2014) Heng Deng et al.   Theranostics

Gold-Loaded Polymeric Micelles for Computed Tomography-Guided Radiation Therapy Treatment and Radiosensitization

(2013) Ajlan Al Zaki et al.   ACS Nano

Gold-Coated Fe3O4Nanoroses with Five Unique Functions for Cancer Cell Targeting, Imaging, and Therapy

(2013) Chunmei Li et al.   ADVANCED FUNCTIONAL MATERIALS

Selective cellular uptake and induction of apoptosis of cancer-targeted selenium nanoparticles

(2013) Yanyu Huang et al.   BIOMATERIALS

Selenocystine potentiates cancer cell apoptosis induced by 5-fluorouracil by triggering reactive oxygen species-mediated DNA damage and inactivation of the ERK pathway

(2013) Cundong Fan et al.   FREE RADICAL BIOLOGY AND MEDICINE

The thioredoxin antioxidant system

(2013) Jun Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Core/Satellite Multifunctional Nanotheranostic for in Vivo Imaging and Tumor Eradication by Radiation/Photothermal Synergistic Therapy

(2013) Qingfeng Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rattle-Structured Multifunctional Nanotheranostics for Synergetic Chemo-/Radiotherapy and Simultaneous Magnetic/Luminescent Dual-Mode Imaging

(2013) Wenpei Fan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhancement of Auranofin-Induced Apoptosis in MCF-7 Human Breast Cells by Selenocystine, a Synergistic Inhibitor of Thioredoxin Reductase

(2013) Chaoran Liu et al.   PLoS One

A dinuclear cyclometalated gold(iii)–phosphine complex targeting thioredoxin reductase inhibits hepatocellular carcinoma in vivo

(2013) Raymond Wai-Yin Sun et al.   Chemical Science

Computed tomography imaging-guided radiotherapy by targeting upconversion nanocubes with significant imaging and radiosensitization enhancements

(2013) Huaiyong Xing et al.   Scientific Reports

Functionalized selenium nanoparticles with nephroprotective activity, the important roles of ROS-mediated signaling pathways

(2013) Yinghua Li et al.   Journal of Materials Chemistry B

Selenium Nanoparticles as a Carrier of 5-Fluorouracil to Achieve Anticancer Synergism

(2012) Wen Liu et al.   ACS Nano

On the Biological Properties of Alkynyl Phosphine Gold(I) Complexes

(2012) Andreas Meyer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium complexes containing 2,6-bis(benzimidazolyl)pyridine derivatives induce cancer cell apoptosis by triggering DNA damage-mediated p53 phosphorylation

(2012) Linlin Li et al.   DALTON TRANSACTIONS

Surface decoration of selenium nanoparticles by mushroom polysaccharides–protein complexes to achieve enhanced cellular uptake and antiproliferative activity

(2012) Hualian Wu et al.   JOURNAL OF MATERIALS CHEMISTRY

Mitochondrial Thioredoxin-Responding Off–On Fluorescent Probe

(2012) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular and Cellular Characterization of the Biological Effects of Ruthenium(II) Complexes Incorporating 2-Pyridyl-2-pyrimidine-4-carboxylic Acid

(2012) Vanessa Pierroz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effects of copper nanoparticles on rat cerebral microvessel endothelial cells

(2012) William J Trickler et al.   Nanomedicine

Transforming a Targeted Porphyrin Theranostic Agent into a PET Imaging Probe for Cancer

(2012) Jiyun Shi et al.   Theranostics

Cancer Nanotheranostics: Improving Imaging and Therapy by Targeted Delivery Across Biological Barriers

(2011) Forrest M. Kievit et al.   ADVANCED MATERIALS

The reversal of cisplatin-induced nephrotoxicity by selenium nanoparticles functionalized with 11-mercapto-1-undecanol by inhibition of ROS-mediated apoptosis

(2011) Yinghua Li et al.   BIOMATERIALS

Synthesis and in vitro Anticancer Activities of some Selenadiazole Derivatives

(2010) Daniel Plano et al.   ARCHIV DER PHARMAZIE

Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: An effect attenuated by phycocyanin

(2010) Xiao-Ling Li et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Benzimidazol-2-ylidene Gold(I) Complexes Are Thioredoxin Reductase Inhibitors with Multiple Antitumor Properties

(2010) Riccardo Rubbiani et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mitochondria-mediated apoptosis in human breast carcinoma MCF-7 cells induced by a novel selenadiazole derivative

(2008) Tianfeng Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Selenocystine induces apoptosis of A375 human melanoma cells by activating ROS-mediated mitochondrial pathway and p53 phosphorylation

(2008) T. Chen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Selenium nanoparticles fabricated in Undaria pinnatifida polysaccharide solutions induce mitochondria-mediated apoptosis in A375 human melanoma cells

(2008) Tianfeng Chen et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

New trends for metal complexes with anticancer activity

(2008) Pieter CA Bruijnincx et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Selenocystine induces caspase-independent apoptosis in MCF-7 human breast carcinoma cells with involvement of p53 phosphorylation and reactive oxygen species generation

(2008) Tianfeng Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Selenocystine Induces S-Phase Arrest and Apoptosis in Human Breast Adenocarcinoma MCF-7 Cells by Modulating ERK and Akt Phosphorylation

(2008) Tianfeng Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Determination of Physiological Thiols by Electrochemical Detection with Piazselenole and Its Application in Rat Breast Cancer Cells 4T-1

(2008) Wei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY