Nociceptive neurons detect cytokines in arthritis

Involvement of Peripheral and Spinal Tumor Necrosis Factor α in Spinal Cord Hyperexcitability During Knee Joint Inflammation in Rats

(2013) Christian König et al.   Arthritis & Rheumatology

Interleukin-17 sensitizes joint nociceptors to mechanical stimuli and contributes to arthritic pain through neuronal interleukin-17 receptors in rodents

(2012) Frank Richter et al.   ARTHRITIS AND RHEUMATISM

The role of interleukin-1β in arthritic pain: Main involvement in thermal, but not mechanical, hyperalgesia in rat antigen-induced arthritis

(2012) Matthias Ebbinghaus et al.   ARTHRITIS AND RHEUMATISM

Spinal interleukin-6 is an amplifier of arthritic pain in the rat

(2012) Enrique Vazquez et al.   ARTHRITIS AND RHEUMATISM

Review: Central pain mechanisms in the rheumatic diseases: Future directions

(2012) Kristine Phillips et al.   ARTHRITIS AND RHEUMATISM

Neuronal IL-17 receptor upregulates TRPV4 but not TRPV1 receptors in DRG neurons and mediates mechanical but not thermal hyperalgesia

(2012) Gisela Segond von Banchet et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The Contribution of Spinal Glial Cells to Chronic Pain Behaviour in the Monosodium Iodoacetate Model of Osteoarthritic Pain

(2011) Devi Rani Sagar et al.   Molecular Pain

Genetic Evidence for an Essential Role of Neuronally Expressed IL-6 Signal Transducer gp130 in the Induction and Maintenance of Experimentally Induced Mechanical Hypersensitivity in vivo and in vitro

(2011) Serena Quarta et al.   Molecular Pain

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-17 induces hyperalgesia via TNF-dependent neutrophil infiltration

(2011) Kay E. McNamee et al.   PAIN

Blockade of TNF-α rapidly inhibits pain responses in the central nervous system

(2011) Andreas Hess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spinal tumor necrosis factor α neutralization reduces peripheral inflammation and hyperalgesia and suppresses autonomic responses in experimental arthritis: A role for spinal tumor necrosis factor α during induction and maintenance of peripheral inflammat

(2010) Michael Karl Boettger et al.   ARTHRITIS AND RHEUMATISM

Tumor necrosis factor causes persistent sensitization of joint nociceptors to mechanical stimuli in rats

(2010) Frank Richter et al.   ARTHRITIS AND RHEUMATISM

The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis

(2010) Jan Bondeson et al.   ARTHRITIS AND RHEUMATISM

The IL-17 Family Cytokines in Immunity and Disease

(2010) Rajita Pappu et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Interleukin-17 Contributes to Neuroinflammation and Neuropathic Pain Following Peripheral Nerve Injury in Mice

(2010) Cristina Fabiola Kim et al.   JOURNAL OF PAIN

Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis

(2010) Christina A. Christianson et al.   PAIN

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

(2010) W. Hueber et al.   Science Translational Medicine

Differential effects of locally and systemically administered soluble glycoprotein 130 on pain and inflammation in experimental arthritis

(2010) Michael K Boettger et al.   ARTHRITIS RESEARCH & THERAPY

Molecular Mechanisms of TRPV4-Mediated Neural Signaling

(2009) Wolfgang Liedtke   Annals of the New York Academy of Sciences

Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo

(2009) Roland Axmann et al.   ARTHRITIS AND RHEUMATISM

Interleukin-6 as a key player in systemic inflammation and joint destruction

(2009) J.E. Fonseca et al.   AUTOIMMUNITY REVIEWS

TNFα Mechanically Sensitizes Masseter Muscle Afferent Fibers of Male Rats

(2009) Akhlaq W. Hakim et al.   JOURNAL OF NEUROPHYSIOLOGY

A Key Role for gp130 Expressed on Peripheral Sensory Nerves in Pathological Pain

(2009) M. Andratsch et al.   JOURNAL OF NEUROSCIENCE

Current Challenges in Glia-Pain Biology

(2009) Stephen B. McMahon et al.   NEURON

Experimental arthritis causes tumor necrosis factor-α-dependent infiltration of macrophages into rat dorsal root ganglia which correlates with pain-related behavior

(2009) Gisela Segond von Banchet et al.   PAIN

IL-17 mediates articular hypernociception in antigen-induced arthritis in mice

(2009) Larissa G. Pinto et al.   PAIN

Antinociceptive effects of tumor necrosis factor α neutralization in a rat model of antigen-induced arthritis: Evidence of a neuronal target

(2008) Michael K. Boettger et al.   ARTHRITIS AND RHEUMATISM

Nociceptors Are Interleukin-1  Sensors

(2008) A. M. Binshtok et al.   JOURNAL OF NEUROSCIENCE

Role of interleukin-6 in chronic muscle hyperalgesic priming

(2008) O.A. Dina et al.   NEUROSCIENCE

Effect of cytokines on neuronal excitability

(2008) Maria Schäfers et al.   NEUROSCIENCE LETTERS

Activation of interleukin-1β receptor suppresses the voltage-gated potassium currents in the small-diameter trigeminal ganglion neurons following peripheral inflammation

(2008) Mamoru Takeda et al.   PAIN

IL-17/Th17 targeting: On the road to prevent chronic destructive arthritis?

(2007) Erik Lubberts   CYTOKINE