Interleukin-17 sensitizes joint nociceptors to mechanical stimuli and contributes to arthritic pain through neuronal interleukin-17 receptors in rodents

Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritis

(2012) Niklas Schuelert et al.   ARTHRITIS RESEARCH & THERAPY

Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1β, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: Rationale for combination treatment during arthritis

(2011) Marije I. Koenders et al.   ARTHRITIS AND RHEUMATISM

Th17 Cells, Not IL-17+    T Cells, Drive Arthritic Bone Destruction in Mice and Humans

(2011) B. Pollinger et al.   JOURNAL OF IMMUNOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-17 induces hyperalgesia via TNF-dependent neutrophil infiltration

(2011) Kay E. McNamee et al.   PAIN

Blockade of TNF-α rapidly inhibits pain responses in the central nervous system

(2011) Andreas Hess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells

(2011) U. Baschant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Update on peripheral mechanisms of pain: beyond prostaglandins and cytokines

(2011) Hans-Georg Schaible et al.   ARTHRITIS RESEARCH & THERAPY

Tumor necrosis factor causes persistent sensitization of joint nociceptors to mechanical stimuli in rats

(2010) Frank Richter et al.   ARTHRITIS AND RHEUMATISM

The IL-17 Family Cytokines in Immunity and Disease

(2010) Rajita Pappu et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Interleukin-17 Contributes to Neuroinflammation and Neuropathic Pain Following Peripheral Nerve Injury in Mice

(2010) Cristina Fabiola Kim et al.   JOURNAL OF PAIN

Molecular effects of interleukin-1β on dorsal root ganglion neurons: Prevention of ligand-induced internalization of the bradykinin 2 receptor and downregulation of G protein-coupled receptor kinase 2

(2010) Gisela Segond von Banchet et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Nociceptor sensitization in pain pathogenesis

(2010) Michael S Gold et al.   NATURE MEDICINE

Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis

(2010) Christina A. Christianson et al.   PAIN

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

(2010) W. Hueber et al.   Science Translational Medicine

IL-17 potentiates neuronal injury induced by oxygen–glucose deprivation and affects neuronal IL-17 receptor expression

(2009) Dan-dan Wang et al.   JOURNAL OF NEUROIMMUNOLOGY

Gait abnormalities differentially indicate pain or structural joint damage in monoarticular antigen-induced arthritis

(2009) Michael K. Boettger et al.   PAIN

IL-17 mediates articular hypernociception in antigen-induced arthritis in mice

(2009) Larissa G. Pinto et al.   PAIN

Lessons from animal models of arthritis over the past decade

(2009) Wim Berg   ARTHRITIS RESEARCH & THERAPY

Joint pain

(2009) Hans-Georg Schaible et al.   EXPERIMENTAL BRAIN RESEARCH

Antinociceptive effects of tumor necrosis factor α neutralization in a rat model of antigen-induced arthritis: Evidence of a neuronal target

(2008) Michael K. Boettger et al.   ARTHRITIS AND RHEUMATISM

Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase

(2008) Keiichi Iwanami et al.   ARTHRITIS AND RHEUMATISM

Structure–function relationships in the IL-17 receptor: Implications for signal transduction and therapy

(2008) Fang Shen et al.   CYTOKINE

IL-17/Th17 targeting: On the road to prevent chronic destructive arthritis?

(2007) Erik Lubberts   CYTOKINE