Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis

Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease

(2012) P L Klarenbeek et al.   ANNALS OF THE RHEUMATIC DISEASES

Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis

(2012) Jose U. Scher et al.   ARTHRITIS AND RHEUMATISM

The interplay between endoplasmic reticulum stress and inflammation

(2012) Sumaira Z Hasnain et al.   IMMUNOLOGY AND CELL BIOLOGY

A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis

(2012) Seung-Ah Yoo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis

(2012) Jeremy Sokolove et al.   PLoS One

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

(2012) Soi Law et al.   ARTHRITIS RESEARCH & THERAPY

Optimising treatment in rheumatoid arthritis: a review of potential biological markers of response

(2011) P. Emery et al.   ANNALS OF THE RHEUMATIC DISEASES

Identification and functional characterization of T cells reactive to citrullinated vimentin in HLA-DRB1*0401-positive humanized mice and rheumatoid arthritis patients

(2011) Omri Snir et al.   ARTHRITIS AND RHEUMATISM

Development of the anti-citrullinated protein antibody repertoire prior to the onset of rheumatoid arthritis

(2011) Lotte A. van de Stadt et al.   ARTHRITIS AND RHEUMATISM

Economic consequences and potential benefits

(2011) Bruno Fautrel et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Post-translational modifications of the extracellular matrix are key events in cancer progression: Opportunities for biochemical marker development

(2011) D. J. Leeming et al.   BIOMARKERS

Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients

(2011) N. Giannoukakis et al.   DIABETES CARE

Clinical tolerance in allogeneic hematopoietic stem cell transplantation

(2011) Maria-Grazia Roncarolo et al.   IMMUNOLOGICAL REVIEWS

Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination

(2011) John J Miles et al.   IMMUNOLOGY AND CELL BIOLOGY

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

(2010) J. S. Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis

(2010) R. A. Harry et al.   ANNALS OF THE RHEUMATIC DISEASES

Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses

(2010) Jeroen N. Stoop et al.   ARTHRITIS AND RHEUMATISM

The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner

(2010) Kevin D. Deane et al.   ARTHRITIS AND RHEUMATISM

Epitope-specific immunotherapy of rheumatoid arthritis: Clinical responsiveness occurs with immune deviation and relies on the expression of a cluster of molecules associated with T cell tolerance in a double-blind, placebo-controlled, pilot phase II trial

(2009) Eva C. Koffeman et al.   ARTHRITIS AND RHEUMATISM

Peptidylarginine deiminase 4 and citrullination in health and disease

(2009) Consuelo Anzilotti et al.   AUTOIMMUNITY REVIEWS

Adoptive transfer of IL-10-secreting CD4+CD49b+ regulatory T cells suppresses ongoing arthritis

(2009) Louis-Marie Charbonnier et al.   JOURNAL OF AUTOIMMUNITY

Antigen-Specific Suppression of Inflammatory Arthritis Using Liposomes

(2009) C. Capini et al.   JOURNAL OF IMMUNOLOGY

Simultaneous detection of many T-cell specificities using combinatorial tetramer staining

(2009) Evan W Newell et al.   NATURE METHODS

Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

(2008) D Makrygiannakis et al.   ANNALS OF THE RHEUMATIC DISEASES

Vaccines for Multiple Sclerosis

(2008) Jorge Correale et al.   CNS DRUGS

Class II major histocompatibility complex tetramer staining: progress, problems, and prospects

(2008) Sabrina S. Vollers et al.   IMMUNOLOGY

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice

(2008) Jonathan A. Hill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?

(2008) Ranjeny Thomas et al.   ARTHRITIS RESEARCH & THERAPY