Clinical tolerance in allogeneic hematopoietic stem cell transplantation

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Epigenetic quantification of tumor-infiltrating T-lymphocytes

(2011) Jalid Sehouli et al.   Epigenetics

Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome

(2011) Laura Passerini et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Acute but not chronic graft-versus-host disease is associated with a reduction of circulating CD4+CD25highCD127low/− regulatory T cells

(2010) Sya N. Ukena et al.   ANNALS OF HEMATOLOGY

Progress in hematopoietic stem cell transplantation as allogeneic cellular gene therapy in thalassemia

(2010) Antonella Isgrò et al.   Annals of the New York Academy of Sciences

A Genomic Approach to Human Autoimmune Diseases

(2010) Virginia Pascual et al.   Annual Review of Immunology

Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway

(2010) S. Gregori et al.   BLOOD

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

The role of HLA-G in immunity and hematopoiesis

(2010) Edgardo D. Carosella et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Discontinuation of calcineurin inhibitors treatment allows the development of FOXP3+ regulatory T-cells in patients after kidney transplantation

(2010) Jacqueline van de Wetering et al.   CLINICAL TRANSPLANTATION

Minor histocompatibility antigens: presentation principles, recognition logic and the potential for a healing hand

(2010) Charles T Spencer et al.   Current Opinion in Organ Transplantation

Granulocyte-colony stimulating factor drives the in vitro differentiation of human dendritic cells that induce anergy in naïve T cells

(2010) Maura Rossetti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular and functional characterization of allogantigen-specific anergic T cells suitable for cell therapy

(2010) R. Bacchetta et al.   HAEMATOLOGICA

Quantitatively different red cell/nucleated cell chimerism in patients with long-term, persistent hematopoietic mixed chimerism after bone marrow transplantation for thalassemia major or sickle cell disease

(2010) M. Andreani et al.   HAEMATOLOGICA

The Mammalian Target of Rapamycin: Linking T Cell Differentiation, Function, and Metabolism

(2010) Jonathan D. Powell et al.   IMMUNITY

Induction of anergic allergen-specific suppressor T cells using tolerogenic dendritic cells derived from children with allergies to house dust mites

(2010) Valentina Pacciani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Low-dose, but not high-dose, cyclosporin A promotes regulatory T-cell induction, expansion, or both

(2010) Ria Baumgrass et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transplantation of hematopoietic stem cells and long-term survival for primary immunodeficiencies in Europe: Entering a new century, do we do better?

(2010) Andrew R. Gennery et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

(2010) Pervinder Sagoo et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of a B cell signature associated with renal transplant tolerance in humans

(2010) Kenneth A. Newell et al.   JOURNAL OF CLINICAL INVESTIGATION

Mucosal Anti-CD3 Monoclonal Antibody Attenuates Collagen-Induced Arthritis That Is Associated with Induction of LAP+ Regulatory T Cells and Is Enhanced by Administration of an Emulsome-Based Th2-Skewing Adjuvant

(2010) H. Y. Wu et al.   JOURNAL OF IMMUNOLOGY

Infant colitis—it's in the genes

(2010) Erik-Oliver Glocker et al.   LANCET

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

IL-35-mediated induction of a potent regulatory T cell population

(2010) Lauren W Collison et al.   NATURE IMMUNOLOGY

Human Antigen-Specific Regulatory T Cells Generated by T Cell Receptor Gene Transfer

(2010) Todd M. Brusko et al.   PLoS One

CD4+CD25+ Regulatory T Cell Depletion Improves the Graft-Versus-Tumor Effect of Donor Lymphocytes After Allogeneic Hematopoietic Stem Cell Transplantation

(2010) S. Maury et al.   Science Translational Medicine

Elafin Is a Biomarker of Graft-Versus-Host Disease of the Skin

(2010) S. Paczesny et al.   Science Translational Medicine

Potential T regulatory cell therapy in transplantation: how far have we come and how far can we go?

(2010) Manuela Battaglia   TRANSPLANT INTERNATIONAL

Hematopoietic Cell Transplantation for Autoimmune Disease: Updates from Europe and the United States

(2009) Keith M. Sullivan et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Relapse after Allogeneic Hematopoietic Cell Therapy

(2009) Marcel R.M. van den Brink et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Long-term outcome after hematopoietic stem cell transplantation of a single-center cohort of 90 patients with severe combined immunodeficiency

(2009) B. Neven et al.   BLOOD

Haploidentical stem cell transplantation after a reduced-intensity conditioning regimen for the treatment of advanced hematologic malignancies: posttransplantation CD8-depleted donor lymphocyte infusions contribute to improve T-cell recovery

(2009) Anna Dodero et al.   BLOOD

Purified T-depleted, CD34+ peripheral blood and bone marrow cell transplantation from haploidentical mother to child with thalassemia

(2009) P. Sodani et al.   BLOOD

How I treat ADA deficiency

(2009) H. B. Gaspar et al.   BLOOD

Escalating doses of donor lymphocytes for incipient graft rejection following SCT for thalassemia

(2009) I Frugnoli et al.   BONE MARROW TRANSPLANTATION

A Preliminary Gene Expression Profile of Acute Graft-Versus-Host Disease

(2009) Matthew P. Buzzeo et al.   CELL TRANSPLANTATION

Immunomagnetic isolation of CD4+CD25+FoxP3+natural T regulatory lymphocytes for clinical applications

(2009) M. Di Ianni et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells

(2009) Piotr Trzonkowski et al.   CLINICAL IMMUNOLOGY

Immunosuppressive Drugs and Tregs: A Critical Evaluation!

(2009) S. A. De Serres et al.   Clinical Journal of the American Society of Nephrology

Immune tolerance in allergy

(2009) Mübeccel Akdis   CURRENT OPINION IN IMMUNOLOGY

Antigen-Specific Dependence of Tr1-Cell Therapy in Preclinical Models of Islet Transplant

(2009) N. Gagliani et al.   DIABETES

The Tregs' world according to GARP

(2009) Manuela Battaglia et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Type 1 regulatory T cells are associated with persistent split erythroid/lymphoid chimerism after allogeneic hematopoietic stem cell transplantation for thalassemia

(2009) G. Serafini et al.   HAEMATOLOGICA

Role of human leukocyte antigen-G in the induction of adaptive type 1 regulatory T cells

(2009) Silvia Gregori et al.   HUMAN IMMUNOLOGY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

Low-dose of tacrolimus favors the induction of functional CD4+CD25+FoxP3+ regulatory T cells in solid-organ transplantation

(2009) Zhen Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Clinical grade production of IL-10 producing regulatory Tr1 lymphocytes for cell therapy of chronic inflammatory diseases

(2009) Valérie Brun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Identification and characterization of IL-10/IFN-γ–producing effector-like T cells with regulatory function in human blood

(2009) Barbara Häringer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Isolation of functional human regulatory T cells (Treg) from the peripheral blood based on the CD39 expression

(2009) Magis Mandapathil et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Cutting Edge: Plasmacytoid Dendritic Cells Induce IL-10 Production in T Cells via the Delta-Like-4/Notch Axis

(2009) N. Kassner et al.   JOURNAL OF IMMUNOLOGY

Ikaros Is a Regulator of Il10 Expression in CD4+ T Cells

(2009) S. E. Umetsu et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cell Suppression Is Potentiated by Target T Cells in a Cell Contact, IL-35- and IL-10-Dependent Manner

(2009) Lauren W. Collison et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells

(2009) C. Pot et al.   JOURNAL OF IMMUNOLOGY

Graft-versus-host disease

(2009) James LM Ferrara et al.   LANCET

Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I–II study

(2009) Fabio Ciceri et al.   LANCET ONCOLOGY

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2

(2009) T. Okamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells

(2009) R. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of IL-17-producing FOXP3+ regulatory T cells in humans

(2009) K. S. Voo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent advances on the non-classical major histocompatibility complex class I HLA-G molecule

(2009) C. Menier et al.   TISSUE ANTIGENS

Increased frequency of regulatory T Cells and selection of highly potent CD62L+ cells during treatment of human lung transplant recipients with rapamycin

(2009) Christian M. Lange et al.   TRANSPLANT INTERNATIONAL

Impact of Immunosuppressive Drugs on CD4+CD25+FOXP3+ Regulatory T Cells: Does In Vitro Evidence Translate to the Clinical Setting?

(2009) Ahmet Demirkiran et al.   TRANSPLANTATION

Increased Interleukin-10 Production Without Expansion of CD4+CD25+ T-Regulatory Cells in Early Stable Renal Transplant Patients on Calcineurin Inhibitors

(2009) Sharad K. Mittal et al.   TRANSPLANTATION

IL10 and IL10 Receptor Gene Variation and Outcomes After Unrelated and Related Hematopoietic Cell Transplantation

(2009) Li-Hui Tseng et al.   TRANSPLANTATION

Conversion From Calcineurin Inhibitor to Mycophenolate Mofetil-Based Immunosuppression Changes the Frequency and Phenotype of CD4+FOXP3+ Regulatory T Cells

(2009) Ahmet Demirkiran et al.   TRANSPLANTATION

CD4+CD25+FOXP3+Regulatory T Cells Increase De Novo in Kidney Transplant Patients After Immunodepletion with Campath-1H

(2008) D. D. Bloom et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Rabbit ATG but not horse ATG promotes expansion of functional CD4+CD25highFOXP3+ regulatory T cells in vitro

(2008) X. Feng et al.   BLOOD

A survey of fully haploidentical hematopoietic stem cell transplantation in adults with high-risk acute leukemia: a risk factor analysis of outcomes for patients in remission at transplantation

(2008) F. Ciceri et al.   BLOOD

A biomarker panel for acute graft-versus-host disease

(2008) S. Paczesny et al.   BLOOD

Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies

(2008) J. K. Davies et al.   BLOOD

IL-17 contributes to CD4-mediated graft-versus-host disease

(2008) L. W. Kappel et al.   BLOOD

In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations

(2008) M. J. Carlson et al.   BLOOD

Haploidentical SCT in children: an update and future perspectives

(2008) P Lang et al.   BONE MARROW TRANSPLANTATION

Hematopoietic cell transplantation for correction of primary immunodeficiencies

(2008) A H Filipovich   BONE MARROW TRANSPLANTATION

Extracorporeal photopheresis for the treatment of steroid refractory acute GVHD

(2008) P Perfetti et al.   BONE MARROW TRANSPLANTATION

Rapamycin Monotherapy in Patients With Type 1 Diabetes Modifies CD4+CD25+FOXP3+ Regulatory T-Cells

(2008) P. Monti et al.   DIABETES

Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections

(2008) Sang-Jun Ha et al.   IMMUNOLOGICAL REVIEWS

CD4+T-regulatory cells: toward therapy for human diseases

(2008) Sarah E. Allan et al.   IMMUNOLOGICAL REVIEWS

HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression

(2008) Tatsuo Kawai et al.   NEW ENGLAND JOURNAL OF MEDICINE

Notch regulates IL-10 production by T helper 1 cells

(2008) S. Rutz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical impact of natural killer cell reconstitution after allogeneic hematopoietic transplantation

(2008) Andrea Velardi et al.   Seminars in Immunopathology

Tolerance versus immune response — MicroRNAs as important elements in the regulation of the HLA-G gene expression

(2008) T.D. Veit et al.   TRANSPLANT IMMUNOLOGY

HLA-G: from biology to clinical benefits

(2008) Edgardo D. Carosella et al.   TRENDS IN IMMUNOLOGY

Cellular and humoral responses to tetanus vaccination in gabonese children

(2008) E. van Riet et al.   VACCINE

Advances in the allogeneic transplantation for thalassemia

(2007) Guido Lucarelli et al.   BLOOD REVIEWS