Necroptosis: An emerging type of cell death in liver diseases

Necroptosis in Solid Organ Transplantation: A Missing Link to Immune Activation?

(2013) R. B. Mannon   AMERICAN JOURNAL OF TRANSPLANTATION

RIPK3-Mediated Necroptosis Promotes Donor Kidney Inflammatory Injury and Reduces Allograft Survival

(2013) A. Lau et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The mechanism of necroptosis in normal and cancer cells

(2013) Simone Fulda   CANCER BIOLOGY & THERAPY

Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis

(2013) Jianfeng Wu et al.   CELL RESEARCH

TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death

(2013) Justyna Sosna et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RIP3: a molecular switch for necrosis and inflammation

(2013) K. Moriwaki et al.   GENES & DEVELOPMENT

Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice

(2013) Anup Ramachandran et al.   HEPATOLOGY

Anti-Necroptosis Chemical Necrostatin-1 Can Also Suppress Apoptotic and Autophagic Pathway to Exert Neuroprotective Effect in Mice Intracerebral Hemorrhage Model

(2013) Pan Chang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Protective Effects of Necrostatin-1 against Concanavalin A-Induced Acute Hepatic Injury in Mice

(2013) Yingqun Zhou et al.   MEDIATORS OF INFLAMMATION

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

(2013) A. Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis

(2013) Stephen W.G. Tait et al.   Cell Reports

Inhibition of Apoptosis Protects Mice from Ethanol-Mediated Acceleration of Early Markers of CCl4-Induced Fibrosis but not Steatosis or Inflammation

(2012) Sanjoy Roychowdhury et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways

(2012) Zhigao Wang et al.   CELL

TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation

(2012) S Jouan-Lanhouet et al.   CELL DEATH AND DIFFERENTIATION

Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury

(2012) Sanjoy Roychowdhury et al.   HEPATOLOGY

ARC is a novel therapeutic approach against acetaminophen-induced hepatocellular necrosis

(2012) Junfeng An et al.   JOURNAL OF HEPATOLOGY

Rip1 (Receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

(2012) Andreas Linkermann et al.   KIDNEY INTERNATIONAL

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(2012) Andreas Linkermann et al.   MOLECULAR MEDICINE

Necrostatin-1 Suppresses Autophagy and Apoptosis in Mice Traumatic Brain Injury Model

(2012) Yao-Qi Wang et al.   NEUROCHEMICAL RESEARCH

Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

(2012) N Takahashi et al.   Cell Death & Disease

New components of the necroptotic pathway

(2012) Zhenru Zhou et al.   Protein & Cell

NEMO and RIP1 Control Cell Fate in Response to Extensive DNA Damage via TNF-α Feedforward Signaling

(2011) Sharon Biton et al.   CELL

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Necroptosis: An emerging form of programmed cell death

(2011) Wei Wu et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

NO donor induces Nec-1-inhibitable, but RIP1-independent, necrotic cell death in pancreatic β-cells

(2011) Yoshiaki Tamura et al.   FEBS LETTERS

RIP1-Dependent and Independent Effects of Necrostatin-1 in Necrosis and T Cell Activation

(2011) YoungSik Cho et al.   PLoS One

The Dual Functions of Receptor Interacting Protein 1 in Fas-Induced Hepatocyte Death During Sepsis

(2011) Sam I. McNeal et al.   SHOCK

TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

(2011) N Vanlangenakker et al.   Cell Death & Disease

Virus Inhibition of RIP3-Dependent Necrosis

(2010) Jason W. Upton et al.   Cell Host & Microbe

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model

(2009) Daniel M. Rosenbaum et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cell Death

(2009) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology

Expansion and evolution of cell death programmes

(2008) Alexei Degterev et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY