Metabolomic insights into the intricate gut microbial–host interaction in the development of obesity and type 2 diabetes

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

(2015) Saeed Shoaie et al.   Cell Metabolism

Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine- N -Oxide

(2015) Kymberleigh A. Romano et al.   mBio

The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance

(2015) Manya Warrier et al.   Cell Reports

Metabonomic study of biochemical changes in urinary of type 2 diabetes mellitus patients after the treatment of sulfonylurea antidiabetic drugs based on ultra-performance liquid chromatography/mass spectrometry

(2014) Taoguang Huo et al.   BIOMEDICAL CHROMATOGRAPHY

The human microbiome and bile acid metabolism: dysbiosis, dysmetabolism, disease and intervention

(2014) Mitchell L Jones et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Improved Metabolic Health Alters Host Metabolism in Parallel with Changes in Systemic Xeno-Metabolites of Gut Origin

(2014) Caitlin Campbell et al.   PLoS One

Bacterial Bile Metabolising Gene Abundance in Crohn's, Ulcerative Colitis and Type 2 Diabetes Metagenomes

(2014) Alain Labbé et al.   PLoS One

Impact of the gut microbiota on the development of obesity and type 2 diabetes mellitus

(2014) Isabel Moreno-Indias et al.   Frontiers in Microbiology

Application of combined omics platforms to accelerate biomedical discovery in diabesity

(2013) Irwin J. Kurland et al.   Annals of the New York Academy of Sciences

Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity

(2013) Anne Vrieze et al.   JOURNAL OF HEPATOLOGY

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Systemic Perturbations of Key Metabolites in Diabetic Rats During the Evolution of Diabetes Studied by Urine Metabonomics

(2013) Mimi Guan et al.   PLoS One

Gender-Specific Metabolomic Profiling of Obesity in Leptin-Deficient ob/ob Mice by 1H NMR Spectroscopy

(2013) Eun-Young Won et al.   PLoS One

Nicotinuric Acid: A potential marker of metabolic syndrome through a metabolomics-based approach

(2012) C.-F. Huang et al.   DIABETES CARE

Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women

(2012) Evelyne M Dewulf et al.   GUT

Nutrimetabolomic Strategies To Develop New Biomarkers of Intake and Health Effects

(2012) Rafael Llorach et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The gut microbiota, obesity and insulin resistance

(2012) Jian Shen et al.   MOLECULAR ASPECTS OF MEDICINE

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Understanding the role of gut microbes and probiotics in obesity: How far are we?

(2012) Yolanda Sanz et al.   PHARMACOLOGICAL RESEARCH

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

(2012) S. Craciun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Interaction Between Obesity and the Gut Microbiota: Relevance in Nutrition

(2011) Nathalie M. Delzenne et al.   Annual Review of Nutrition

Bile Acid Metabolism and the Pathogenesis of Type 2 Diabetes

(2011) Janne Prawitt et al.   Current Diabetes Reports

The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus

(2011) R. S. Kootte et al.   DIABETES OBESITY & METABOLISM

Circulating lipopolysaccharide-binding protein (LBP) as a marker of obesity-related insulin resistance

(2011) J M Moreno-Navarrete et al.   INTERNATIONAL JOURNAL OF OBESITY

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Propionate as a health-promoting microbial metabolite in the human gut

(2011) Elham Hosseini et al.   NUTRITION REVIEWS

The Human Serum Metabolome

(2011) Nikolaos Psychogios et al.   PLoS One

Red and Processed Meat Consumption and Risk of Incident Coronary Heart Disease, Stroke, and Diabetes Mellitus

(2010) Renata Micha et al.   CIRCULATION

The clinical significance of betaine, an osmolyte with a key role in methyl group metabolism

(2010) Michael Lever et al.   CLINICAL BIOCHEMISTRY

Role of gut microbiota in the control of energy and carbohydrate metabolism

(2010) Koen Venema   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Obesity, Diabetes, and Gut Microbiota: The hygiene hypothesis expanded?

(2010) G. Musso et al.   DIABETES CARE

A Marker of Endotoxemia Is Associated With Obesity and Related Metabolic Disorders in Apparently Healthy Chinese

(2010) L. Sun et al.   DIABETES CARE

The environment within: how gut microbiota may influence metabolism and body composition

(2010) A. Vrieze et al.   DIABETOLOGIA

Gut microbiome-derived metabolites characterize a peculiar obese urinary metabotype

(2010) R Calvani et al.   INTERNATIONAL JOURNAL OF OBESITY

Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits

(2010) Xinjie Zhao et al.   Metabolomics

High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues

(2010) Olaf Beckonert et al.   Nature Protocols

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting

(2010) Karsten Suhre et al.   PLoS One

Systemic gut microbial modulation of bile acid metabolism in host tissue compartments

(2010) J. R. Swann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Conversion of cholic acid and chenodeoxycholic acid into their 7-oxo derivatives byBacteroides intestinalisAM-1 isolated from human feces

(2009) Satoru Fukiya et al.   FEMS MICROBIOLOGY LETTERS

Obesity and the Microbiota

(2009) Herbert Tilg et al.   GASTROENTEROLOGY

Metabonomic study of biochemical changes in the serum of type 2 diabetes mellitus patients after the treatment of metformin hydrochloride

(2009) Taoguang Huo et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The core gut microbiome, energy balance and obesity

(2009) Peter J. Turnbaugh et al.   JOURNAL OF PHYSIOLOGY-LONDON

Human Serum Metabonomic Analysis Reveals Progression Axes for Glucose Intolerance and Insulin Resistance Statuses

(2009) Xiuying Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Gut Microbiota and Its Possible Relationship With Obesity

(2009) John K. DiBaise et al.   MAYO CLINIC PROCEEDINGS

Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research

(2009) Augustin Scalbert et al.   Metabolomics

Microbiota and SCFA in Lean and Overweight Healthy Subjects

(2009) Andreas Schwiertz et al.   Obesity

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Bile Acids: Chemistry, Pathochemistry, Biology, Pathobiology, and Therapeutics

(2008) A. F. Hofmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Bile acids and signal transduction: Role in glucose homeostasis

(2008) Amy Nguyen et al.   CELLULAR SIGNALLING

Multi-platform investigation of the metabolome in a leptin receptor defective murine model of type 2 diabetes

(2008) Geoffrey T. Gipson et al.   Molecular BioSystems

Targeting bile-acid signalling for metabolic diseases

(2008) Charles Thomas et al.   NATURE REVIEWS DRUG DISCOVERY

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Symbiotic gut microbes modulate human metabolic phenotypes

(2008) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxicological effects of cinnabar in rats by NMR-based metabolic profiling of urine and serum

(2007) Lai Wei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY