Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon

Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract

(2015) Lauren L. Atwell et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Nrf2 Prevents Initiation but Accelerates Progression through the Kras Signaling Pathway during Lung Carcinogenesis

(2013) Hironori Satoh et al.   CANCER RESEARCH

HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates

(2013) Praveen Rajendran et al.   Epigenetics

Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents

(2013) Hanne Fredly et al.   Clinical Epigenetics

Histone deacetylase 3 (HDAC3) participates in the transcriptional repression of thep16INK4agene in mammary gland of the female rat offspring exposed to an early-life high-fat diet

(2012) Shasha Zheng et al.   Epigenetics

Nrf2 knockout enhances intestinal tumorigenesis inApcmin/+mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation

(2012) Ka Lung Cheung et al.   MOLECULAR CARCINOGENESIS

The UCSC Genome Browser database: extensions and updates 2013

(2012) Laurence R. Meyer et al.   NUCLEIC ACIDS RESEARCH

Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors

(2012) Geneviève P Delcuve et al.   Clinical Epigenetics

A role for low-abundance miRNAs in colon cancer: the miR-206/Krüppel-like factor 4 (KLF4) axis

(2012) Mansi A Parasramka et al.   Clinical Epigenetics

Metabolism as a key to histone deacetylase inhibition

(2011) Praveen Rajendran et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly

(2011) Praveen Rajendran et al.   Molecular Cancer

The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression

(2011) W. Wang et al.   NUCLEIC ACIDS RESEARCH

p16Ink4a overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors

(2011) C Romagosa et al.   ONCOGENE

Metabolism and Tissue Distribution of Sulforaphane in Nrf2 Knockout and Wild-Type Mice

(2011) John D. Clarke et al.   PHARMACEUTICAL RESEARCH

Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells

(2011) Praveen Rajendran et al.   Clinical Epigenetics

NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

(2010) Rong Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Histone deacetylase inhibitor (SAHA) and repression of EZH2 synergistically inhibit proliferation of gallbladder carcinoma

(2009) Junpei Yamaguchi et al.   CANCER SCIENCE

Nrf2: friend or foe for chemoprevention?

(2009) T. W. Kensler et al.   CARCINOGENESIS

The transcription factor ZBP-89 suppresses p16 expression through a histone modification mechanism to affect cell senescence

(2009) Yunpeng Feng et al.   FEBS Journal

Histone deacetylase inhibitors: Potential in cancer therapy

(2009) P.A. Marks et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Epigenetic Therapies Move Into New Territory, but How Exactly Do They Work?

(2009) R. S. Tuma   JNCI-Journal of the National Cancer Institute

Increased Susceptibility of Nrf2 Knockout Mice to Colitis-Associated Colorectal Cancer

(2008) T. O. Khor et al.   Cancer Prevention Research

Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter

(2008) H. Nian et al.   CARCINOGENESIS

Histone deacetylases: novel targets for prevention of colitis-associated cancer in mice

(2008) R. Glauben et al.   GUT