Cinnamide Derivatives ofd-Mannose as Inhibitors of the Bacterial Virulence Factor LecB fromPseudomonas aeruginosa

Synthesis of mannoheptose derivatives and their evaluation as inhibitors of the lectin LecB from the opportunistic pathogen Pseudomonas aeruginosa

(2015) Anna Hofmann et al.   CARBOHYDRATE RESEARCH

Glycomimetics versus Multivalent Glycoconjugates for the Design of High Affinity Lectin Ligands

(2014) Samy Cecioni et al.   CHEMICAL REVIEWS

A Biophysical Study with Carbohydrate Derivatives Explains the Molecular Basis of Monosaccharide Selectivity of the Pseudomonas aeruginosa Lectin LecB

(2014) Roman Sommer et al.   PLoS One

A lipid zipper triggers bacterial invasion

(2014) T. Eierhoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of Two Classes of Potent Glycomimetic Inhibitors of Pseudomonas aeruginosa LecB with Distinct Binding Modes

(2013) Dirk Hauck et al.   ACS Chemical Biology

Kinetic Properties of Carbohydrate-Lectin Interactions: FimH Antagonists

(2013) Meike Scharenberg et al.   ChemMedChem

New Approaches to Control Infections: Anti-biofilm Strategies against Gram-negative Bacteria

(2013) Roman Sommer et al.   CHIMIA

Molecular determinants of drug–receptor binding kinetics

(2013) Albert C. Pan et al.   DRUG DISCOVERY TODAY

Applying insights from biofilm biology to drug development — can a new approach be developed?

(2013) Thomas Bjarnsholt et al.   NATURE REVIEWS DRUG DISCOVERY

Multivalent glycoconjugates as anti-pathogenic agents

(2012) Anna Bernardi et al.   CHEMICAL SOCIETY REVIEWS

Inhalation with Fucose and Galactose for Treatment of Pseudomonas Aeruginosa in Cystic Fibrosis Patients

(2012) Hans-Peter Hauber et al.   International Journal of Medical Sciences

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Pseudomonas Aeruginosa: Resistance to the Max

(2011) Keith Poole   Frontiers in Microbiology

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Hospital-Acquired Infections Due to Gram-Negative Bacteria

(2010) Anton Y. Peleg et al.   NEW ENGLAND JOURNAL OF MEDICINE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Role of LecA and LecB Lectins in Pseudomonas aeruginosa-Induced Lung Injury and Effect of Carbohydrate Ligands

(2009) C. Chemani et al.   INFECTION AND IMMUNITY

Structural Artifacts in Protein−Ligand X-ray Structures: Implications for the Development of Docking Scoring Functions

(2009) Chresten R. Søndergaard et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition and Dispersion of Pseudomonas aeruginosa Biofilms by Glycopeptide Dendrimers Targeting the Fucose-Specific Lectin LecB

(2008) Emma M.V. Johansson et al.   CHEMISTRY & BIOLOGY

Glycomimetics and Glycodendrimers as High Affinity Microbial Anti-adhesins

(2008) Anne Imberty et al.   CHEMISTRY-A EUROPEAN JOURNAL