Regulation of mesenchymal stem cell 3D microenvironment: From macro to microfluidic bioreactors
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Regulation of mesenchymal stem cell 3D microenvironment: From macro to microfluidic bioreactors
Authors
Keywords
-
Journal
Biotechnology Journal
Volume 11, Issue 1, Pages 43-57
Publisher
Wiley
Online
2015-12-23
DOI
10.1002/biot.201500191
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Biomanufacturing of human mesenchymal stem cells in cell therapy: Influence of microenvironment on scalable expansion in bioreactors
- (2016) Teng Ma et al. BIOCHEMICAL ENGINEERING JOURNAL
- Expansion of human mesenchymal stem cells in fibrous bed bioreactor
- (2016) Ang-Chen Tsai et al. BIOCHEMICAL ENGINEERING JOURNAL
- Mechanical characterization of human mesenchymal stem cells subjected to cyclic uniaxial strain and TGF-β1
- (2015) Mohammad-Mehdi Khani et al. Journal of the Mechanical Behavior of Biomedical Materials
- Hydrostatic pressure promotes the proliferation and osteogenic/chondrogenic differentiation of mesenchymal stem cells: The roles of RhoA and Rac1
- (2015) Yin-Hua Zhao et al. Stem Cell Research
- Three-dimensional hypoxic culture of human mesenchymal stem cells encapsulated in a photocurable, biodegradable polymer hydrogel: A potential injectable cellular product for nucleus pulposus regeneration
- (2014) Deepak Kumar et al. Acta Biomaterialia
- Matrix-driven formation of mesenchymal stem cell–extracellular matrix microtissues on soft alginate hydrogels
- (2014) F. Raquel Maia et al. Acta Biomaterialia
- Optimizing design and fabrication of microfluidic devices for cell cultures: An effective approach to control cell microenvironment in three dimensions
- (2014) G. Pagano et al. Biomicrofluidics
- Effects of scaffold architecture on mechanical characteristics and osteoblast response to static and perfusion bioreactor cultures
- (2014) Michal Bartnikowski et al. BIOTECHNOLOGY AND BIOENGINEERING
- Efficient myogenic commitment of human mesenchymal stem cells on biomimetic materials replicating myoblast topography
- (2014) Eunjee A. Lee et al. Biotechnology Journal
- Modulation of the stemness and osteogenic differentiation of human mesenchymal stem cells by controlling RGD concentrations of poly(carboxybetaine) hydrogel
- (2014) Hsiu-Wen Chien et al. Biotechnology Journal
- Microfluidic platform generates oxygen landscapes for localized hypoxic activation
- (2014) Megan L. Rexius-Hall et al. LAB ON A CHIP
- Flow Characterization of a Spinner Flask for Induced Pluripotent Stem Cell Culture Application
- (2014) Mohd-Zulhilmi Ismadi et al. PLoS One
- Lab-on-a-chip technologies for stem cell analysis
- (2014) Peter Ertl et al. TRENDS IN BIOTECHNOLOGY
- The role of RhoA kinase (ROCK) in cell alignment on nanofibers
- (2013) Mohammad Nahid Andalib et al. Acta Biomaterialia
- Monitoring the mineralisation of bone nodules in vitro by space- and time-resolved Raman micro-spectroscopy
- (2013) Adrian Ghita et al. ANALYST
- Modulation of bone marrow mesenchymal stem cell secretome by ECM-like hydrogels
- (2013) Nuno A. Silva et al. BIOCHIMIE
- Differential regulation of stiffness, topography, and dimension of substrates in rat mesenchymal stem cells
- (2013) Zhan Li et al. BIOMATERIALS
- Substrate-dependent Wnt signaling in MSC differentiation within biomaterial-derived 3D spheroids
- (2013) Shan-hui Hsu et al. BIOMATERIALS
- Non-invasive monitoring of cell metabolism and lipid production in 3D engineered human adipose tissues using label-free multiphoton microscopy
- (2013) Tyler Chang et al. BIOMATERIALS
- The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells
- (2013) Andrew R. Cameron et al. BIOMATERIALS
- Deconstructing stem cell population heterogeneity: Single-cell analysis and modeling approaches
- (2013) Jincheng Wu et al. BIOTECHNOLOGY ADVANCES
- Bioreactor engineering of stem cell environments
- (2013) Nina Tandon et al. BIOTECHNOLOGY ADVANCES
- Bioreactor design for clinical-grade expansion of stem cells
- (2013) Francisco F. dos Santos et al. Biotechnology Journal
- Engineering stem cell fate with biochemical and biomechanical properties of microcarriers
- (2013) Sébastien Sart et al. BIOTECHNOLOGY PROGRESS
- Cellular behavior in micropatterned hydrogels by bioprinting system depended on the cell types and cellular interaction
- (2013) Soyoung Hong et al. JOURNAL OF BIOSCIENCE AND BIOENGINEERING
- Microenvironment Is Involved in Cellular Response to Hydrostatic Pressures During Chondrogenesis of Mesenchymal Stem Cells
- (2013) Rui Ye et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Exploring the roles of integrin binding and cytoskeletal reorganization during mesenchymal stem cell mechanotransduction in soft and stiff hydrogels subjected to dynamic compression
- (2013) Andrew J. Steward et al. Journal of the Mechanical Behavior of Biomedical Materials
- Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels
- (2013) Sudhir Khetan et al. NATURE MATERIALS
- The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine
- (2013) Paolo Bianco et al. NATURE MEDICINE
- The Role of Paracrine and Autocrine Signaling in the Early Phase of Adipogenic Differentiation of Adipose-derived Stem Cells
- (2013) Mette Hemmingsen et al. PLoS One
- Orchestrating osteogenic differentiation of mesenchymal stem cells-identification of placental growth factor as a mechanosensitive gene with a pro-osteogenic role
- (2013) Ryan J. McCoy et al. STEM CELLS
- Inhibitory Effects of Hypoxia on Metabolic Switch and Osteogenic Differentiation of Human Mesenchymal Stem Cells
- (2013) Shu-Han Hsu et al. STEM CELLS
- Mesenchymal Stem Cell and Chondrocyte Fates in a Multishear Microdevice Are Regulated by Yes-Associated Protein
- (2013) Weiliang Zhong et al. STEM CELLS AND DEVELOPMENT
- Three-Dimensional Aggregates of Mesenchymal Stem Cells: Cellular Mechanisms, Biological Properties, and Applications
- (2013) Sébastien Sart et al. TISSUE ENGINEERING PART B-REVIEWS
- Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment
- (2013) Hon Fai Chan et al. Scientific Reports
- Quantitative metabolic imaging using endogenous fluorescence to detect stem cell differentiation
- (2013) Kyle P. Quinn et al. Scientific Reports
- Bioreactor monitoring with spectroscopy and chemometrics: a review
- (2012) N. D. Lourenço et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Droplet Microfluidics-A Tool for Single-Cell Analysis
- (2012) Haakan N. Joensson et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cyclic strain dominates over microtopography in regulating cytoskeletal and focal adhesion remodeling of human mesenchymal stem cells
- (2012) Golnar Doroudian et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Stem cell regulation by the Hippo pathway
- (2012) Samantha E. Hiemer et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Molecular characterization of heterogeneous mesenchymal stem cells with single-cell transcriptomes
- (2012) Zhongjun Li et al. BIOTECHNOLOGY ADVANCES
- Regulation of autocrine fibroblast growth factor-2 signaling by perfusion flow in 3D human mesenchymal stem cell constructs
- (2012) Junho Kim et al. BIOTECHNOLOGY PROGRESS
- Fluid Flow and Cell Proliferation of Mesenchymal Adipose-Derived Stem Cells in Small-Scale, Stirred, Single-Use Bioreactors
- (2012) Stephan Kaiser et al. CHEMIE INGENIEUR TECHNIK
- Fluid flow stress induced contraction and re-spread of mesenchymal stem cells: a microfluidic study
- (2012) Wenfu Zheng et al. Integrative Biology
- Microcarrier-based Expansion Process for hMSCs with High Vitality and Undifferentiated Characteristics
- (2012) Christiane L. Elseberg et al. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
- Modular polylactic acid microparticle-based scaffolds prepared via microfluidic emulsion/solvent displacement process: Fabrication, characterization, andin vitromesenchymal stem cells interaction study
- (2012) A. Salerno et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Autocrine fibroblast growth factor 2-mediated interactions between human mesenchymal stem cells and the extracellular matrix under varying oxygen tension
- (2012) Junho Kim et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Full range physiological mass transport control in 3D tissue cultures
- (2012) Yu-Hsiang Hsu et al. LAB ON A CHIP
- Transduction of mechanical and cytoskeletal cues by YAP and TAZ
- (2012) Georg Halder et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Model microgravity enhances endothelium differentiation of mesenchymal stem cells
- (2012) Xiaofeng Zhang et al. NATURWISSENSCHAFTEN
- OXPHOS Supercomplexes as a Hallmark of the Mitochondrial Phenotype of Adipogenic Differentiated Human MSCs
- (2012) Andreas D. Hofmann et al. PLoS One
- Chip-Based Comparison of the Osteogenesis of Human Bone Marrow- and Adipose Tissue-Derived Mesenchymal Stem Cells under Mechanical Stimulation
- (2012) Sang-Hyug Park et al. PLoS One
- Contrasting Effects of Vasculogenic Induction Upon Biaxial Bioreactor Stimulation of Mesenchymal Stem Cells and Endothelial Progenitor Cells Cocultures in Three-Dimensional Scaffolds Under In Vitro and In Vivo Paradigms for Vascularized Bone Tissue Engineering
- (2012) Yuchun Liu et al. TISSUE ENGINEERING PART A
- The Hippo pathway regulates stem cell proliferation, self-renewal, and differentiation
- (2012) Huan Liu et al. Protein & Cell
- Wnt5a-mediating neurogenesis of human adipose tissue-derived stem cells in a 3D microfluidic cell culture system
- (2011) Jeein Choi et al. BIOMATERIALS
- Effect of uniaxial stretch on morphology and cytoskeleton of human mesenchymal stem cells: static vs. dynamic loading
- (2011) Zahra Goli-Malekabadi et al. Biomedical Engineering-Biomedizinische Technik
- Stem cell cultivation in bioreactors
- (2011) Carlos A.V. Rodrigues et al. BIOTECHNOLOGY ADVANCES
- Perfusion regulation of hMSC microenvironment and osteogenic differentiation in 3D scaffold
- (2011) Junho Kim et al. BIOTECHNOLOGY AND BIOENGINEERING
- Regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells in PEG-ECM hydrogels
- (2011) Nathaniel S. Hwang et al. CELL AND TISSUE RESEARCH
- Biomimetic Platforms for Human Stem Cell Research
- (2011) Gordana Vunjak-Novakovic et al. Cell Stem Cell
- A simple elastic membrane-based microfluidic chip for the proliferation and differentiation of mesenchymal stem cells under tensile stress
- (2011) Xinghua Gao et al. ELECTROPHORESIS
- Microfluidic Mixing: A Review
- (2011) Chia-Yen Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Microfluidic Perfusion for Regulating Diffusible Signaling in Stem Cells
- (2011) Katarina Blagovic et al. PLoS One
- Temporal Activation of β-Catenin Signaling in the Chondrogenic Process of Mesenchymal Stem Cells Affects the Phenotype of the Cartilage Generated
- (2011) Zheng Yang et al. STEM CELLS AND DEVELOPMENT
- A comparison of bioreactors for culture of fetal mesenchymal stem cells for bone tissue engineering
- (2010) Zhi-Yong Zhang et al. BIOMATERIALS
- Mechanisms for osteogenic differentiation of human mesenchymal stem cells induced by fluid shear stress
- (2010) Liyue Liu et al. Biomechanics and Modeling in Mechanobiology
- Droplet-based microfluidic platforms for single T cell secretion analysis of IL-10 cytokine
- (2010) Tania Konry et al. BIOSENSORS & BIOELECTRONICS
- Optimizing the medium perfusion rate in bone tissue engineering bioreactors
- (2010) Warren L. Grayson et al. BIOTECHNOLOGY AND BIOENGINEERING
- Glucose Reduction Prevents Replicative Senescence and Increases Mitochondrial Respiration in Human Mesenchymal Stem Cells
- (2010) Ting Lo et al. CELL TRANSPLANTATION
- Fundamentals of microfluidic cell culture in controlled microenvironments
- (2010) Edmond W. K. Young et al. CHEMICAL SOCIETY REVIEWS
- Biological applications of microfluidic gradient devices
- (2010) Sudong Kim et al. Integrative Biology
- Computational fluid dynamics modeling of momentum transport in rotating wall perfused bioreactor for cartilage tissue engineering
- (2010) Mahmut N. Cinbiz et al. JOURNAL OF BIOTECHNOLOGY
- Detection of the osteogenic differentiation of mesenchymal stem cells in 2D and 3D cultures by electrochemical impedance spectroscopy
- (2010) Cornelia Hildebrandt et al. JOURNAL OF BIOTECHNOLOGY
- The metabolism of human mesenchymal stem cells during proliferation and differentiation
- (2010) Girish Pattappa et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate
- (2010) Nathaniel Huebsch et al. NATURE MATERIALS
- Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties
- (2010) T. J. Bartosh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Review on Mixing in Microfluidics
- (2010) Yong Kweon Suh et al. Micromachines
- Establishment of Three-Dimensional Tissue-engineered Bone Constructs Under Microgravity-simulated Conditions
- (2009) Fang Jin et al. ARTIFICIAL ORGANS
- Effects of cyclic stretch on proliferation of mesenchymal stem cells and their differentiation to smooth muscle cells
- (2009) Samane Ghazanfari et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The effect of matrix stiffness on mesenchymal stem cell differentiation in a 3D thixotropic gel
- (2009) Y. Shona Pek et al. BIOMATERIALS
- A microfabricated platform for high-throughput unconfined compression of micropatterned biomaterial arrays
- (2009) Christopher Moraes et al. BIOMATERIALS
- Modeling fluid flow through irregular scaffolds for perfusion bioreactors
- (2009) Frédéric Maes et al. BIOTECHNOLOGY AND BIOENGINEERING
- Cells in 3D matrices under interstitial flow: Effects of extracellular matrix alignment on cell shear stress and drag forces
- (2009) John A. Pedersen et al. JOURNAL OF BIOMECHANICS
- Mechanically induced osteogenic differentiation - the role of RhoA, ROCKII and cytoskeletal dynamics
- (2009) E. J. Arnsdorf et al. JOURNAL OF CELL SCIENCE
- Perfusion affects the tissue developmental patterns of human mesenchymal stem cells in 3D scaffolds
- (2009) Feng Zhao et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Microfluidic platform for controlling the differentiation of embryoid bodies
- (2009) Wai-To Fung et al. LAB ON A CHIP
- Non-Canonical Wnt Signaling and N-Cadherin Related β-Catenin Signaling Play a Role in Mechanically Induced Osteogenic Cell Fate
- (2009) Emily J. Arnsdorf et al. PLoS One
- Droplet microfluidic technology for single-cell high-throughput screening
- (2009) E. Brouzes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Shear Stress Induces Nitric Oxide–Mediated Vascular Endothelial Growth Factor Production in Human Adipose Tissue Mesenchymal Stem Cells
- (2009) Vinícius Bassaneze et al. STEM CELLS AND DEVELOPMENT
- Quantifying In Vitro Growth and Metabolism Kinetics of Human Mesenchymal Stem Cells Using a Mathematical Model
- (2009) Gustavo Higuera et al. TISSUE ENGINEERING PART A
- Dynamic Three-Dimensional Culture Methods Enhance Mesenchymal Stem Cell Properties and Increase Therapeutic Potential
- (2009) Jessica E. Frith et al. TISSUE ENGINEERING PART C-METHODS
- A gel-free 3D microfluidic cell culture system
- (2008) Siew-Min Ong et al. BIOMATERIALS
- Mesenchymal Stem Cells: Revisiting History, Concepts, and Assays
- (2008) Paolo Bianco et al. Cell Stem Cell
- Wnt signaling controls the fate of mesenchymal stem cells
- (2008) Ling Ling et al. GENE
- Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: A role for AKT and hypoxia‐inducible factor (HIF)‐1α
- (2008) Manoj Kanichai et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells
- (2008) M. Chabert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emergence of Patterned Stem Cell Differentiation Within Multicellular Structures
- (2008) Sami Alom Ruiz et al. STEM CELLS
- Modulation of Stem Cell Shape and Fate B: Mechanical Modulation of Cell Shape and Gene Expression
- (2008) Sara H. McBride et al. TISSUE ENGINEERING PART A
- Modulation of Stem Cell Shape and Fate A: The Role of Density and Seeding Protocol on Nucleus Shape and Gene Expression
- (2008) Sara H. McBride et al. TISSUE ENGINEERING PART A
- Hepatogenic differentiation of mesenchymal stem cells using microfluidic chips
- (2007) Xiuli Ju et al. Biotechnology Journal
- Biomolecular gradients in cell culture systems
- (2007) Thomas M. Keenan et al. LAB ON A CHIP
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started