Journal
ANALYST
Volume 139, Issue 1, Pages 55-58Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3an01716h
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Funding
- Biotechnology and Biological Sciences Research Council [BB/G010285/1] Funding Source: Medline
- Medical Research Council [G0601750] Funding Source: Medline
- BBSRC [BB/G010285/1] Funding Source: UKRI
- MRC [G0601750] Funding Source: UKRI
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Raman microscopy was used as a label-free method to study the mineralisation of bone nodules formed by mesenchymal stem cells cultured in osteogenic medium in vitro. Monitoring individual bone nodules over 28 days revealed temporal and spatial changes in the crystalline phase of the hydroxyapatite components of the nodules.
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