Orchestrating osteogenic differentiation of mesenchymal stem cells-identification of placental growth factor as a mechanosensitive gene with a pro-osteogenic role

Innovative Collagen Nano-Hydroxyapatite Scaffolds Offer a Highly Efficient Non-Viral Gene Delivery Platform for Stem Cell-Mediated Bone Formation

(2012) Caroline M. Curtin et al.   ADVANCED MATERIALS

Forcing Stem Cells to Behave: A Biophysical Perspective of the Cellular Microenvironment

(2012) Yubing Sun et al.   Annual Review of Biophysics

Influence of flow rate and scaffold pore size on cell behavior during mechanical stimulation in a flow perfusion bioreactor

(2012) R.J. McCoy et al.   BIOTECHNOLOGY AND BIOENGINEERING

Mechanical regulation of signaling pathways in bone

(2012) William R. Thompson et al.   GENE

Hypoxia-driven pathways in bone development, regeneration and disease

(2012) Christa Maes et al.   Nature Reviews Rheumatology

Primary Cilia-Mediated Mechanotransduction in Human Mesenchymal Stem Cells

(2012) David A. Hoey et al.   STEM CELLS

The development of non-viral gene-activated matrices for bone regeneration using polyethyleneimine (PEI) and collagen-based scaffolds

(2011) Erica G. Tierney et al.   JOURNAL OF CONTROLLED RELEASE

Mesenchymal stem cell fate is regulated by the composition and mechanical properties of collagen–glycosaminoglycan scaffolds

(2011) Ciara M. Murphy et al.   Journal of the Mechanical Behavior of Biomedical Materials

Mechanically Induced Focal Adhesion Assembly Amplifies Anti-Adipogenic Pathways in Mesenchymal Stem Cells

(2011) Buer Sen et al.   STEM CELLS

Reactive oxygen species derived from Nox4 mediateBMP2gene transcription and osteoblast differentiation

(2010) Chandi C. Mandal et al.   BIOCHEMICAL JOURNAL

Three hours of perfusion culture prior to 28 days of static culture, enhances osteogenesis by human cells in a collagen GAG scaffold

(2010) Michael B. Keogh et al.   BIOTECHNOLOGY AND BIOENGINEERING

Growth factor delivery-based tissue engineering: general approaches and a review of recent developments

(2010) K. Lee et al.   Journal of the Royal Society Interface

Influence of Shear Stress in Perfusion Bioreactor Cultures for the Development of Three-Dimensional Bone Tissue Constructs: A Review

(2010) Ryan J. McCoy et al.   TISSUE ENGINEERING PART B-REVIEWS

Novel Role of NADPH Oxidase in Angiogenesis and Stem/Progenitor Cell Function

(2009) Masuko Ushio-Fukai et al.   ANTIOXIDANTS & REDOX SIGNALING

The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering

(2009) Ciara M. Murphy et al.   BIOMATERIALS

Mechanically induced osteogenic differentiation - the role of RhoA, ROCKII and cytoskeletal dynamics

(2009) E. J. Arnsdorf et al.   JOURNAL OF CELL SCIENCE

Low-magnitude high-frequency mechanical signals accelerate and augment endochondral bone repair: Preliminary evidence of efficacy

(2009) Allen E. Goodship et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Bone Marrow–Derived Mesenchymal Stem Cells Promote Angiogenic Processes in a Time- and Dose-Dependent Manner In Vitro

(2009) Garry P. Duffy et al.   TISSUE ENGINEERING PART A

Novel Freeze-Drying Methods to Produce a Range of Collagen–Glycosaminoglycan Scaffolds with Tailored Mean Pore Sizes

(2009) Matthew G. Haugh et al.   TISSUE ENGINEERING PART C-METHODS

Vascular endothelial growth factor regulates osteoblast survival – evidence for an autocrine feedback mechanism

(2009) John Street et al.   Journal of Orthopaedic Surgery and Research

Co-regulation of constitutive nitric oxide synthases and NADPH oxidase by the small GTPase Rac

(2008) Balakrishnan Selvakumar et al.   FEBS LETTERS

Bone Formation During Distraction Osteogenesis Is Dependent on Both VEGFR1 and VEGFR2 Signaling

(2008) Kimberly A Jacobsen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Loss of trabeculae by mechano-biological means may explain rapid bone loss in osteoporosis

(2008) B. M Mulvihill et al.   Journal of the Royal Society Interface

Deformation simulation of cells seeded on a collagen-GAG scaffold in a flow perfusion bioreactor using a sequential 3D CFD-elastostatics model

(2008) C. Jungreuthmayer et al.   MEDICAL ENGINEERING & PHYSICS

Emergence of Patterned Stem Cell Differentiation Within Multicellular Structures

(2008) Sami Alom Ruiz et al.   STEM CELLS

Mechanical Stimulation of Osteoblasts Using Steady and Dynamic Fluid Flow

(2008) Michael J. Jaasma et al.   TISSUE ENGINEERING PART A

Design and validation of a dynamic flow perfusion bioreactor for use with compliant tissue engineering scaffolds

(2007) Michael J. Jaasma et al.   JOURNAL OF BIOTECHNOLOGY

The Effects of Twelve Weeks of Bed Rest on Bone Histology, Biochemical Markers of Bone Turnover, and Calcium Homeostasis in Eleven Normal Subjects

(2006) Joseph E. Zerwekh et al.   JOURNAL OF BONE AND MINERAL RESEARCH