Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction

Role of Nucleotide Binding and GTPase Domain Dimerization in Dynamin-like Myxovirus Resistance Protein A for GTPase Activation and Antiviral Activity

(2015) Alexej Dick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Triple-Arginine Motif in the Amino-Terminal Domain and Oligomerization Are Required for HIV-1 Inhibition by Human MX2

(2015) Caroline Goujon et al.   JOURNAL OF VIROLOGY

The Effect of Species Representation on the Detection of Positive Selection in Primate Gene Data Sets

(2015) Ross M. McBee et al.   MOLECULAR BIOLOGY AND EVOLUTION

Mx GTPases: dynamin-like antiviral machines of innate immunity

(2015) Otto Haller et al.   TRENDS IN MICROBIOLOGY

APOBECs and virus restriction

(2015) Reuben S. Harris et al.   VIROLOGY

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition

(2015) John L. Goodier et al.   PLoS Genetics

Structural Insight into HIV-1 Restriction by MxB

(2014) Jennifer L. Fribourgh et al.   Cell Host & Microbe

Host and Viral Determinants of Mx2 Antiretroviral Activity

(2014) Idoia Busnadiego et al.   JOURNAL OF VIROLOGY

Transfer of the Amino-Terminal Nuclear Envelope Targeting Domain of Human MX2 Converts MX1 into an HIV-1 Resistance Factor

(2014) C. Goujon et al.   JOURNAL OF VIROLOGY

Evolutionary Analysis Identifies an MX2 Haplotype Associated with Natural Resistance to HIV-1 Infection

(2014) Manuela Sironi et al.   MOLECULAR BIOLOGY AND EVOLUTION

Host and viral determinants for MxB restriction of HIV-1 infection

(2014) Kenneth A Matreyek et al.   Retrovirology

The Interferon-Inducible MxB Protein Inhibits HIV-1 Infection

(2013) Zhenlong Liu et al.   Cell Host & Microbe

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

(2013) Caroline Goujon et al.   NATURE

MX2 is an interferon-induced inhibitor of HIV-1 infection

(2013) Melissa Kane et al.   NATURE

Host gene evolution traces the evolutionary history of ancient primate lentiviruses

(2013) A. A. Compton et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Porcine alpha interferon inhibit Japanese encephalitis virus replication by different ISGs in vitro

(2013) Ke Liu et al.   RESEARCH IN VETERINARY SCIENCE

Convergence and Divergence in the Evolution of the APOBEC3G-Vif Interaction Reveal Ancient Origins of Simian Immunodeficiency Viruses

(2013) Alex A. Compton et al.   PLoS Pathogens

Rules of Engagement: Molecular Insights from Host-Virus Arms Races

(2012) Matthew D. Daugherty et al.   Annual Review of Genetics

An ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammals

(2012) Carsten Münk et al.   BMC EVOLUTIONARY BIOLOGY

Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA

(2012) Patrick S. Mitchell et al.   Cell Host & Microbe

The Host Restriction Factor APOBEC3G and Retroviral Vif Protein Coevolve due to Ongoing Genetic Conflict

(2012) Alex A. Compton et al.   Cell Host & Microbe

Extensive evolutionary and functional diversity among mammalian AIM2-like receptors

(2012) Rebecca L. Brunette et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A cross-species view on viruses

(2012) Sara L Sawyer et al.   Current Opinion in Virology

Structure of Myxovirus Resistance Protein A Reveals Intra- and Intermolecular Domain Interactions Required for the Antiviral Function

(2011) Song Gao et al.   IMMUNITY

A high-resolution map of human evolutionary constraint using 29 mammals

(2011) Kerstin Lindblad-Toh et al.   NATURE

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

Dynamin-like MxA GTPase: Structural Insights into Oligomerization and Implications for Antiviral Activity

(2010) Otto Haller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human MxA Protein: An Interferon-Induced Dynamin-Like GTPase with Broad Antiviral Activity

(2010) Otto Haller et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Ancient Adaptive Evolution of Tetherin Shaped the Functions of Vpu and Nef in Human Immunodeficiency Virus and Primate Lentiviruses

(2010) E. S. Lim et al.   JOURNAL OF VIROLOGY

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

Molecular evolution of the antiretroviral TRIM5 gene

(2009) Welkin E. Johnson et al.   IMMUNOGENETICS

An expanded clade of rodent Trim5 genes

(2009) Semih U. Tareen et al.   VIROLOGY

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

Phylogeny.fr: robust phylogenetic analysis for the non-specialist

(2008) A. Dereeper et al.   NUCLEIC ACIDS RESEARCH

TRIMCyp expression in Old World primates Macaca nemestrina and Macaca fascicularis

(2008) G. Brennan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species

(2008) C. A. Virgen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Independent evolution of an antiviral TRIMCyp in rhesus macaques

(2008) S. J. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of a TRIM5-CypA Splice Isoform in Old World Monkeys

(2008) Ruchi M. Newman et al.   PLoS Pathogens