Evolutionary Analysis Identifies an MX2 Haplotype Associated with Natural Resistance to HIV-1 Infection

Exploring the Occurrence of Classic Selective Sweeps in Humans Using Whole-Genome Sequencing Data Sets

(2014) Maud Fagny et al.   MOLECULAR BIOLOGY AND EVOLUTION

An Evolutionary Analysis of Antigen Processing and Presentation across Different Timescales Reveals Pervasive Selection

(2014) Diego Forni et al.   PLoS Genetics

Endoplasmic reticulum aminopeptidase 2 haplotypes play a role in modulating susceptibility to HIV infection

(2013) Mara Biasin et al.   AIDS

Identifying Recent Adaptations in Large-Scale Genomic Data

(2013) Sharon R. Grossman et al.   CELL

The Interferon-Inducible MxB Protein Inhibits HIV-1 Infection

(2013) Zhenlong Liu et al.   Cell Host & Microbe

A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A

(2013) J. Lane et al.   HUMAN MOLECULAR GENETICS

A 175 Million Year History of T Cell Regulatory Molecules Reveals Widespread Selection, with Adaptive Evolution of Disease Alleles

(2013) Diego Forni et al.   IMMUNITY

A single nucleotide polymorphism of porcine MX2 gene provides antiviral activity against vesicular stomatitis virus

(2013) Keisuke Sasaki et al.   IMMUNOGENETICS

Mx Proteins: Antiviral Gatekeepers That Restrain the Uninvited

(2013) J. Verhelst et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

(2013) Caroline Goujon et al.   NATURE

MX2 is an interferon-induced inhibitor of HIV-1 infection

(2013) Melissa Kane et al.   NATURE

Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls

(2013) Paul J. McLaren et al.   PLoS Pathogens

Alzheimer Disease Susceptibility Loci: Evidence for a Protein Network under Natural Selection

(2012) Towfique Raj et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Rules of Engagement: Molecular Insights from Host-Virus Arms Races

(2012) Matthew D. Daugherty et al.   Annual Review of Genetics

Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA

(2012) Patrick S. Mitchell et al.   Cell Host & Microbe

Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol

(2012) Su-Yang Liu et al.   IMMUNITY

Multicohort Genomewide Association Study Reveals a New Signal of Protection Against HIV-1 Acquisition

(2012) S. Limou et al.   JOURNAL OF INFECTIOUS DISEASES

A Genetic Polymorphism of FREM1 Is Associated with Resistance against HIV Infection in the Pumwani Sex Worker Cohort

(2012) M. Luo et al.   JOURNAL OF VIROLOGY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Systematic identification of type I and type II interferon-induced antiviral factors

(2012) S.-Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detecting Individual Sites Subject to Episodic Diversifying Selection

(2012) Ben Murrell et al.   PLoS Genetics

GeCo++: a C++ library for genomic features computation and annotation in the presence of variants

(2011) M. Cereda et al.   BIOINFORMATICS

Structure of Myxovirus Resistance Protein A Reveals Intra- and Intermolecular Domain Interactions Required for the Antiviral Function

(2011) Song Gao et al.   IMMUNITY

A Common Polymorphism in TLR3 Confers Natural Resistance to HIV-1 Infection

(2011) M. Sironi et al.   JOURNAL OF IMMUNOLOGY

A Random Effects Branch-Site Model for Detecting Episodic Diversifying Selection

(2011) Sergei L. Kosakovsky Pond et al.   MOLECULAR BIOLOGY AND EVOLUTION

A Population Genetics-Phylogenetics Approach to Inferring Natural Selection in Coding Sequences

(2011) Daniel J. Wilson et al.   PLoS Genetics

Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection

(2010) Alexandra Zhernakova et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology

(2010) W. Delport et al.   BIOINFORMATICS

Human MxA Protein: An Interferon-Induced Dynamin-Like GTPase with Broad Antiviral Activity

(2010) Otto Haller et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

(2009) Matteo Fumagalli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

(2009) Luis B. Barreiro et al.   PLoS Genetics

The ‘immunologic advantage’ of HIV-exposed seronegative individuals

(2008) Masaaki Miyazawa et al.   AIDS

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS

Antiretroelement Activity of APOBEC3H Was Lost Twice in Recent Human Evolution

(2008) Molly OhAinle et al.   Cell Host & Microbe

Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation

(2008) J. Z. Li et al.   SCIENCE