Resolution of macropinosomes, phagosomes and autolysosomes: Osmotically driven shrinkage enables tubulation and vesiculation

SLC15A2 and SLC15A4 Mediate the Transport of Bacterially Derived Di/Tripeptides To Enhance the Nucleotide-Binding Oligomerization Domain–Dependent Immune Response in Mouse Bone Marrow–Derived Macrophages

(2018) Yongjun Hu et al.   JOURNAL OF IMMUNOLOGY

Drinking problems: mechanisms of macropinosome formation and maturation

(2017) Catherine M. Buckley et al.   FEBS Journal

Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport

(2017) Arunas Kvainickas et al.   JOURNAL OF CELL BIOLOGY

Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR

(2017) Boris Simonetti et al.   JOURNAL OF CELL BIOLOGY

Human TRPML1 channel structures in open and closed conformations

(2017) Philip Schmiege et al.   NATURE

Structural basis of dual Ca2+/pH regulation of the endolysosomal TRPML1 channel

(2017) Minghui Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Design principles for robust vesiculation in clathrin-mediated endocytosis

(2017) Julian E. Hassinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuning the ion selectivity of two-pore channels

(2017) Jiangtao Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of dual Ca2+/pH regulation of the endolysosomal TRPML1 channel

(2017) Minghui Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Clathrin-Independent Endocytosis Suppresses Cancer Cell Blebbing and Invasion

(2017) Mikkel Roland Holst et al.   Cell Reports

PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment

(2016) Shefali Krishna et al.   DEVELOPMENTAL CELL

WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors

(2016) Catherine M. Buckley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages

(2016) Johnathan Canton et al.   Nature Communications

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

(2015) Manuele Rebsamen et al.   NATURE

Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1

(2015) S. Wang et al.   SCIENCE

Function and dysfunction of two-pore channels

(2015) Sandip Patel   Science Signaling

Physical principles of membrane remodelling during cell mechanoadaptation

(2015) Anita Joanna Kosmalska et al.   Nature Communications

Function and dysfunction of two-pore channels

(2015) Sandip Patel   Science Signaling

Recent developments in the field of bending rigidity measurements on membranes

(2014) Rumiana Dimova   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Convergent regulation of the lysosomal two-pore channel-2 by Mg2+, NAADP, PI(3,5)P2 and multiple protein kinases

(2014) A. Jha et al.   EMBO JOURNAL

Endosomes are specialized platforms for bacterial sensing and NOD2 signalling

(2014) Norihiro Nakamura et al.   NATURE

TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation

(2014) A. R. Mantegazza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retromer: A Master Conductor of Endosome Sorting

(2014) C. Burd et al.   Cold Spring Harbor Perspectives in Biology

Tetrandrine blocks autophagic flux and induces apoptosis via energetic impairment in cancer cells

(2014) W Qiu et al.   Cell Death & Disease

mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State

(2013) Chunlei Cang et al.   CELL

A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

(2013) Florian Steinberg et al.   NATURE CELL BIOLOGY

Identification of Genes Affecting Vacuole Membrane Fragmentation in Saccharomyces cerevisiae

(2013) Lydie Michaillat et al.   PLoS One

Autophagy in lysosomal storage disorders

(2012) Andrew P. Lieberman et al.   Autophagy

TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion Channels in Endosomes and Lysosomes

(2012) Xiang Wang et al.   CELL

Curvature, Lipid Packing, and Electrostatics of Membrane Organelles: Defining Cellular Territories in Determining Specificity

(2012) Joëlle Bigay et al.   DEVELOPMENTAL CELL

Hyaluronidase 1 and β-Hexosaminidase Have Redundant Functions in Hyaluronan and Chondroitin Sulfate Degradation

(2012) Lara Gushulak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositide isoforms determine compartment-specific ion channel activity

(2012) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical feedback between membrane tension and dynamics

(2012) Nils C. Gauthier et al.   TRENDS IN CELL BIOLOGY

The Cell Biology of Phagocytosis

(2011) Ronald S. Flannagan et al.   Annual Review of Pathology-Mechanisms of Disease

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

Identification of SLC38A7 (SNAT7) Protein as a Glutamine Transporter Expressed in Neurons

(2011) Maria G. A. Hägglund et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A complete deficiency of Hyaluronoglucosaminidase 1 (HYAL1) presenting as familial juvenile idiopathic arthritis

(2011) Lisa Imundo et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation

(2011) Y. Rong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overview of the mucopolysaccharidoses

(2011) J. Muenzer   RHEUMATOLOGY

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Equilibrative Nucleoside Transporter 3 Deficiency Perturbs Lysosome Function and Macrophage Homeostasis

(2011) C.-L. Hsu et al.   SCIENCE

Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella

(2010) Markus C Kerr et al.   EMBO JOURNAL

Termination of autophagy and reformation of lysosomes regulated by mTOR

(2010) Li Yu et al.   NATURE

PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

(2010) Xian-ping Dong et al.   Nature Communications

Physiology of Cell Volume Regulation in Vertebrates

(2009) Else K. Hoffmann et al.   PHYSIOLOGICAL REVIEWS

An Initial Step of GAS-Containing Autophagosome-Like Vacuoles Formation Requires Rab7

(2009) Hitomi Yamaguchi et al.   PLoS Pathogens

The yeast lysosome-like vacuole: Endpoint and crossroads

(2008) Sheena Claire Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

(2008) Claudine Kraft et al.   NATURE CELL BIOLOGY