Polarized but Differential Localization and Recruitment of STIM1, Orai1 and TRPC Channels in Secretory Cells

A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels

(2009) Takumi Kawasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

Ribosome-free Terminals of Rough ER Allow Formation of STIM1 Puncta and Segregation of STIM1 from IP3 Receptors

(2009) Gyorgy Lur et al.   CURRENT BIOLOGY

An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs

(2009) Kyu Pil Lee et al.   FEBS LETTERS

Deletion of TRPC3 in Mice Reduces Store-Operated Ca2+ Influx and the Severity of Acute Pancreatitis

(2009) Min Seuk Kim et al.   GASTROENTEROLOGY

ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia

(2009) Christie-Ann McCarl et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Intracellular Loop of Orai1 Plays a Central Role in Fast Inactivation of Ca2+Release-activated Ca2+Channels

(2009) Sonal Srikanth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Native Store-operated Ca2+Influx Requires the Channel Function of Orai1 and TRPC1

(2009) Min Seuk Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRPC3 Regulates Agonist-stimulated Ca2+Mobilization by Mediating the Interaction between Type I Inositol 1,4,5-Trisphosphate Receptor, RACK1, and Orai1

(2009) Geoffrey E. Woodard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

(2009) Joseph P. Yuan et al.   NATURE CELL BIOLOGY

STIM1Mutation Associated with a Syndrome of Immunodeficiency and Autoimmunity

(2009) Capucine Picard et al.   NEW ENGLAND JOURNAL OF MEDICINE

A role for Orai in TRPC-mediated Ca2+ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca2+ entry

(2009) Y. Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversible translocation of EYFP-tagged STIM1 is coupled to calcium influx in insulin secreting β-cells

(2008) Natalia A. Tamarina et al.   CELL CALCIUM

Complex Actions of 2-Aminoethyldiphenyl Borate on Store-operated Calcium Entry

(2008) Wayne I. DeHaven et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Requirement for Orai1 in Store-operated TRPC1-STIM1 Channels

(2008) Kwong Tai Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Slc26a4 transporter functions as an electroneutral Cl−/I−/HCO3−exchanger: role of Slc26a4 and Slc26a6 in I−and HCO3−secretion and in regulation of CFTR in the parotid duct

(2008) Nikolay Shcheynikov et al.   JOURNAL OF PHYSIOLOGY-LONDON

2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels

(2008) Christine Peinelt et al.   JOURNAL OF PHYSIOLOGY-LONDON

STIM1 Gates TRPC Channels, but Not Orai1, by Electrostatic Interaction

(2008) Weizhong Zeng et al.   MOLECULAR CELL

Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels

(2008) Y. Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation

(2008) M. I. Lioudyno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polarized Calcium Signaling in Exocrine Gland Cells

(2007) Ole H. Petersen et al.   Annual Review of Physiology