The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family

Quantifying foot-and-mouth disease virus transmission rates using published data

(2016) Nesya Goris   ALTEX-Alternatives to Animal Experimentation

The Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active Site

(2014) L. Vives-Adrian et al.   JOURNAL OF VIROLOGY

Binding of Glutathione to Enterovirus Capsids Is Essential for Virion Morphogenesis

(2014) Hendrik Jan Thibaut et al.   PLoS Pathogens

Role of Motif B Loop in Allosteric Regulation of RNA-Dependent RNA Polymerization Activity

(2013) Damià Garriga et al.   JOURNAL OF MOLECULAR BIOLOGY

A Template RNA Entry Channel in the Fingers Domain of the Poliovirus Polymerase

(2012) Matthew G. Kortus et al.   JOURNAL OF MOLECULAR BIOLOGY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors

(2011) Grace Campagnola et al.   ANTIVIRAL RESEARCH

Amiloride Is a Competitive Inhibitor of Coxsackievirus B3 RNA Polymerase

(2011) E. V. Gazina et al.   JOURNAL OF VIROLOGY

Comparative Production Analysis of Three Phlebovirus Nucleoproteins under Denaturing or Non-Denaturing Conditions for Crystallographic Studies

(2011) Violaine Lantez et al.   PLoS Neglected Tropical Diseases

Inhibition of enterovirus 71 replication and the viral 3D polymerase by aurintricarboxylic acid

(2010) H.-C. Hung et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Inhibition of Dengue Virus Polymerase by Blocking of the RNA Tunnel

(2010) P. Niyomrattanakit et al.   JOURNAL OF VIROLOGY

Inhibitors of Foot and Mouth Disease Virus Targeting a Novel Pocket of the RNA-Dependent RNA Polymerase

(2010) Ryan C. Durk et al.   PLoS One

Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase

(2010) P. Gong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China

(2010) Yang Wu et al.   Protein & Cell

Novel Antiviral Agent DTriP-22 Targets RNA-Dependent RNA Polymerase of Enterovirus 71

(2009) T.-C. Chen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mutations in the Nonstructural Protein 3A Confer Resistance to the Novel Enterovirus Replication Inhibitor TTP-8307

(2009) A. M. De Palma et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections

(2009) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase

(2009) Cristina Ferrer-Orta et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Saffold Virus, a Human Theiler's-Like Cardiovirus, Is Ubiquitous and Causes Infection Early in Life

(2009) Jan Zoll et al.   PLoS Pathogens

Synthesis and anti-CVB 3 evaluation of substituted 5-nitro-2-phenoxybenzonitriles

(2008) Gerhard Pürstinger et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Crystal Structure of Coxsackievirus B3 RNA-Dependent RNA Polymerase in Complex with Its Protein Primer VPg Confirms the Existence of a Second VPg Binding Site on Picornaviridae Polymerases

(2008) A. Gruez et al.   JOURNAL OF VIROLOGY

The Thiazolobenzimidazole TBZE-029 Inhibits Enterovirus Replication by Targeting a Short Region Immediately Downstream from Motif C in the Nonstructural Protein 2C

(2008) A. M. De Palma et al.   JOURNAL OF VIROLOGY

Crystal Structure of Coxsackievirus B3 3Dpol Highlights the Functional Importance of Residue 5 in Picornavirus Polymerases

(2008) G. Campagnola et al.   JOURNAL OF VIROLOGY

Determinants of RNA-Dependent RNA Polymerase (In)fidelity Revealed by Kinetic Analysis of the Polymerase Encoded by a Foot-and-Mouth Disease Virus Mutant with Reduced Sensitivity to Ribavirin

(2008) A. Arias et al.   JOURNAL OF VIROLOGY

A Critical Role of a Cellular Membrane Traffic Protein in Poliovirus RNA Replication

(2008) George A. Belov et al.   PLoS Pathogens