Inhibitors of Foot and Mouth Disease Virus Targeting a Novel Pocket of the RNA-Dependent RNA Polymerase

Structure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to Ribavirin

(2010) C. Ferrer-Orta et al.   JOURNAL OF VIROLOGY

Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase

(2010) Kamalendra Singh et al.   Viruses-Basel

Mechanism of Hepatitis C Virus RNA Polymerase Inhibition with Dihydroxypyrimidines

(2009) M. H. Powdrill et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections

(2009) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Molecular basis of human immunodeficiency virus drug resistance: An update

(2009) Luis Menéndez-Arias   ANTIVIRAL RESEARCH

Mechanism of Inhibition of HIV-1 Reverse Transcriptase by 4′-Ethynyl-2-fluoro-2′-deoxyadenosine Triphosphate, a Translocation-defective Reverse Transcriptase Inhibitor

(2009) Eleftherios Michailidis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-Based Design of a Benzodiazepine Scaffold Yields a Potent Allosteric Inhibitor of Hepatitis C NS5B RNA Polymerase

(2009) Koen Vandyck et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nucleic acid polymerases use a general acid for nucleotidyl transfer

(2009) Christian Castro et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular Characterization of a Dual Inhibitory and Mutagenic Activity of 5-Fluorouridine Triphosphate on Viral RNA Synthesis. Implications for Lethal Mutagenesis

(2008) Rubén Agudo et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition

(2008) Stefan G. Sarafianos et al.   JOURNAL OF MOLECULAR BIOLOGY

Determinants of RNA-Dependent RNA Polymerase (In)fidelity Revealed by Kinetic Analysis of the Polymerase Encoded by a Foot-and-Mouth Disease Virus Mutant with Reduced Sensitivity to Ribavirin

(2008) A. Arias et al.   JOURNAL OF VIROLOGY

Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors

(2008) Nicolas Sluis-Cremer et al.   VIRUS RESEARCH

Mechanisms of resistance to nucleoside analogue inhibitors of HIV-1 reverse transcriptase

(2008) Luis Menéndez-Arias   VIRUS RESEARCH