The Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active Site

Role of Motif B Loop in Allosteric Regulation of RNA-Dependent RNA Polymerization Activity

(2013) Damià Garriga et al.   JOURNAL OF MOLECULAR BIOLOGY

Structures of Coxsackievirus, Rhinovirus, and Poliovirus Polymerase Elongation Complexes Solved by Engineering RNA Mediated Crystal Contacts

(2013) Peng Gong et al.   PLoS One

A Template RNA Entry Channel in the Fingers Domain of the Poliovirus Polymerase

(2012) Matthew G. Kortus et al.   JOURNAL OF MOLECULAR BIOLOGY

Exploring the Dynamics of Four RNA-Dependent RNA Polymerases by a Coarse-Grained Model

(2012) Hujun Shen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Conformational Changes in Motif D of RdRPs as Fidelity Determinant

(2012) Nuria Verdaguer et al.   STRUCTURE

Motif D of Viral RNA-Dependent RNA Polymerases Determines Efficiency and Fidelity of Nucleotide Addition

(2012) Xiaorong Yang et al.   STRUCTURE

What Is the Role of Motif D in the Nucleotide Incorporation Catalyzed by the RNA-dependent RNA Polymerase from Poliovirus?

(2012) Hujun Shen et al.   PLoS Computational Biology

Picornavirus non-structural proteins as targets for new anti-virals with broad activity

(2011) Heléne Norder et al.   ANTIVIRAL RESEARCH

Molecular Dynamics Simulations of Viral RNA Polymerases Link Conserved and Correlated Motions of Functional Elements to Fidelity

(2011) Ibrahim M. Moustafa et al.   JOURNAL OF MOLECULAR BIOLOGY

Saffold Virus, a Novel Human Cardiovirus with Unknown Pathogenicity

(2011) T. Himeda et al.   JOURNAL OF VIROLOGY

Comparative Production Analysis of Three Phlebovirus Nucleoproteins under Denaturing or Non-Denaturing Conditions for Crystallographic Studies

(2011) Violaine Lantez et al.   PLoS Neglected Tropical Diseases

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to Ribavirin

(2010) C. Ferrer-Orta et al.   JOURNAL OF VIROLOGY

Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase

(2010) P. Gong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

(2010) Rubén Agudo et al.   PLoS Pathogens

Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China

(2010) Yang Wu et al.   Protein & Cell

RNA-dependent RNA polymerases from flaviviruses and Picornaviridae

(2009) Julien Lescar et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase

(2009) Cristina Ferrer-Orta et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Frequent Detection of Highly Diverse Variants of Cardiovirus, Cosavirus, Bocavirus, and Circovirus in Sewage Samples Collected in the United States

(2009) O. Blinkova et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Nucleic acid polymerases use a general acid for nucleotidyl transfer

(2009) Christian Castro et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Splitting statistical potentials into meaningful scoring functions: Testing the prediction of near-native structures from decoy conformations

(2009) Patrick Aloy et al.   BMC STRUCTURAL BIOLOGY

Saffold Virus, a Human Theiler's-Like Cardiovirus, Is Ubiquitous and Causes Infection Early in Life

(2009) Jan Zoll et al.   PLoS Pathogens

The Crystal Structure of Coxsackievirus B3 RNA-Dependent RNA Polymerase in Complex with Its Protein Primer VPg Confirms the Existence of a Second VPg Binding Site on Picornaviridae Polymerases

(2008) A. Gruez et al.   JOURNAL OF VIROLOGY

Phylogenetic Analysis of the Species Theilovirus: Emerging Murine and Human Pathogens

(2008) Z. Liang et al.   JOURNAL OF VIROLOGY

Crystal Structure of Coxsackievirus B3 3Dpol Highlights the Functional Importance of Residue 5 in Picornavirus Polymerases

(2008) G. Campagnola et al.   JOURNAL OF VIROLOGY