A Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus Nucleoprotein

Identification of a novel multiple kinase inhibitor with potent antiviral activity against influenza virus by reducing viral polymerase activity

(2014) Yutaka Sasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of Distant Drug Off-Targets by Direct Superposition of Binding Pocket Surfaces

(2014) Marcel Schumann et al.   PLoS One

Comparative Analysis of Seven Viral Nuclear Export Signals (NESs) Reveals the Crucial Role of Nuclear Export Mediated by the Third NES Consensus Sequence of Nucleoprotein (NP) in Influenza A Virus Replication

(2014) Nopporn Chutiwitoonchai et al.   PLoS One

Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1

(2013) Qingxiang Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Colocalization of Different Influenza Viral RNA Segments in the Cytoplasm before Viral Budding as Shown by Single-molecule Sensitivity FISH Analysis

(2013) Yi-ying Chou et al.   PLoS Pathogens

Monomeric Nucleoprotein of Influenza A Virus

(2013) Sylvie Chenavas et al.   PLoS Pathogens

The influence of lipophilicity in drug discovery and design

(2012) John A Arnott et al.   Expert Opinion on Drug Discovery

Identification and Characterization of Three Novel Nuclear Export Signals in the Influenza A Virus Nucleoprotein

(2012) M. Yu et al.   JOURNAL OF VIROLOGY

ProBiS-2012: web server and web services for detection of structurally similar binding sites in proteins

(2012) J. Konc et al.   NUCLEIC ACIDS RESEARCH

The Structure of Native Influenza Virion Ribonucleoproteins

(2012) R. Arranz et al.   SCIENCE

Mapping the Phosphoproteome of Influenza A and B Viruses by Mass Spectrometry

(2012) Edward C. Hutchinson et al.   PLoS Pathogens

Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease

(2012) Rebecca M. DuBois et al.   PLoS Pathogens

Oligomerization paths of the nucleoprotein of influenza A virus

(2011) B. Tarus et al.   BIOCHIMIE

PoSSuM: a database of similar protein-ligand binding and putative pockets

(2011) J.-I. Ito et al.   NUCLEIC ACIDS RESEARCH

E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors

(2011) Y.-F. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers

(2011) S. W. Gerritz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influenza Virus Ribonucleoprotein Complexes Gain Preferential Access to Cellular Export Machinery through Chromatin Targeting

(2011) Geoffrey P. Chase et al.   PLoS Pathogens

Detection of E119V and E119I Mutations in Influenza A (H3N2) Viruses Isolated from an Immunocompromised Patient: Challenges in Diagnosis of Oseltamivir Resistance

(2010) M. Okomo-Adhiambo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery of novel antiviral agents directed against the influenza A virus nucleoprotein using photo-cross-linked chemical arrays

(2010) Kyoji Hagiwara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Influenza Virus Evolution, Host Adaptation, and Pandemic Formation

(2010) Jeffery K. Taubenberger et al.   Cell Host & Microbe

Crucial role of the influenza virus NS2 (NEP) C-terminal domain in M1 binding and nuclear export of vRNP

(2010) Teppei Shimizu et al.   FEBS LETTERS

Functional Analysis of the Influenza Virus H5N1 Nucleoprotein Tail Loop Reveals Amino Acids That Are Crucial for Oligomerization and Ribonucleoprotein Activities

(2010) W.-H. Chan et al.   JOURNAL OF VIROLOGY

Identification of influenza A nucleoprotein as an antiviral target

(2010) Richard Y Kao et al.   NATURE BIOTECHNOLOGY

Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa

(2009) Aeron C. Hurt et al.   ANTIVIRAL RESEARCH

Infections With Oseltamivir-Resistant Influenza A(H1N1) Virus in the United States

(2009) Nila J. Dharan   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Mutational Analysis of Conserved Amino Acids in the Influenza A Virus Nucleoprotein

(2009) Z. Li et al.   JOURNAL OF VIROLOGY

Crystal structure of an avian influenza polymerase PAN reveals an endonuclease active site

(2009) Puwei Yuan et al.   NATURE

The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

(2009) Alexandre Dias et al.   NATURE

Application of bioinformatics-coupled experimental analysis reveals a new transport-competent nuclear localization signal in the nucleoprotein of Influenza A virus strain

(2008) Krishna Ketha et al.   BMC CELL BIOLOGY

Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design

(2008) Andy Ka-Leung Ng et al.   FASEB JOURNAL

Medical Management of Influenza Infection

(2007) Anne Moscona   Annual Review of Medicine