Vpr Promotes Macrophage-Dependent HIV-1 Infection of CD4+ T Lymphocytes

Efficient transfer of HIV-1 in trans and in cis from Langerhans dendritic cells and macrophages to autologous T lymphocytes

(2014) Maryse Peressin et al.   AIDS

Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing

(2014) Nadine Laguette et al.   CELL

Tetherin Can Restrict Cell-Free and Cell-Cell Transmission of HIV from Primary Macrophages to T Cells

(2014) Sebastian Giese et al.   PLoS Pathogens

HIV-1 Accessory Proteins Adapt Cellular Adaptors to Facilitate Immune Evasion

(2014) David R. Collins et al.   PLoS Pathogens

HIV-1 Vpr—a still “enigmatic multitasker”

(2014) Carolin A. Guenzel et al.   Frontiers in Microbiology

Hepatitis C Therapy With Interferon-α and Ribavirin Reduces CD4 T-Cell–Associated HIV-1 DNA in HIV-1/Hepatitis C Virus–Coinfected Patients

(2013) Hong Sun et al.   JOURNAL OF INFECTIOUS DISEASES

High-Multiplicity HIV-1 Infection and Neutralizing Antibody Evasion Mediated by the Macrophage-T Cell Virological Synapse

(2013) C. J. A. Duncan et al.   JOURNAL OF VIROLOGY

Cell-to-cell spread of HIV-1 and evasion of neutralizing antibodies

(2013) Torben Schiffner et al.   VACCINE

The HIV-1 protein Vpr targets the endoribonuclease Dicer for proteasomal degradation to boost macrophage infection

(2013) Laurieann Casey Klockow et al.   VIROLOGY

Mechanisms of enhanced HIV spread through T-cell virological synapses

(2012) Benjamin M. Dale et al.   IMMUNOLOGICAL REVIEWS

Pegylated Interferon Alfa-2a Monotherapy Results in Suppression of HIV Type 1 Replication and Decreased Cell-Associated HIV DNA Integration

(2012) Livio Azzoni et al.   JOURNAL OF INFECTIOUS DISEASES

Latent HIV-1 Infection Occurs in Multiple Subsets of Hematopoietic Progenitor Cells and Is Reversed by NF- B Activation

(2012) L. A. McNamara et al.   JOURNAL OF VIROLOGY

Neutralization Resistance of Virological Synapse-Mediated HIV-1 Infection Is Regulated by the gp41 Cytoplasmic Tail

(2012) N. D. Durham et al.   JOURNAL OF VIROLOGY

Molecular Mechanisms of HIV Immune Evasion of the Innate Immune Response in Myeloid Cells

(2012) Mike Mashiba et al.   Viruses-Basel

Multiploid Inheritance of HIV-1 during Cell-to-Cell Infection

(2011) A. Del Portillo et al.   JOURNAL OF VIROLOGY

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

(2011) Thomas Pertel et al.   NATURE

The antiviral factor APOBEC3G enhances the recognition of HIV-infected primary T cells by natural killer cells

(2011) Jason M Norman et al.   NATURE IMMUNOLOGY

Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon

(2011) Thomas Pertel et al.   Retrovirology

Immune Evasion and Counteraction of Restriction Factors by HIV-1 and Other Primate Lentiviruses

(2010) Frank Kirchhoff   Cell Host & Microbe

HIV-1 Vpr Loads Uracil DNA Glycosylase-2 onto DCAF1, a Substrate Recognition Subunit of a Cullin 4A-RING E3 Ubiquitin Ligase for Proteasome-dependent Degradation

(2010) Jinwoo Ahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Vpr Induces the K48-Linked Polyubiquitination and Proteasomal Degradation of Target Cellular Proteins To Activate ATR and Promote G2 Arrest

(2010) J.-P. Belzile et al.   JOURNAL OF VIROLOGY

HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs

(2010) Christoph C Carter et al.   NATURE MEDICINE

Dendritic Cells and HIV-1 Trans-Infection

(2010) David McDonald   Viruses-Basel

Antigp41 antibodies fail to block early events of virological synapses but inhibit HIV spread between T cells

(2008) Marta Massanella et al.   AIDS

Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses

(2008) F. Groot et al.   BLOOD