HIV-1 Vpr Loads Uracil DNA Glycosylase-2 onto DCAF1, a Substrate Recognition Subunit of a Cullin 4A-RING E3 Ubiquitin Ligase for Proteasome-dependent Degradation

An interview with Dr. Catherine Transy and Dr. Florence Margottin-Goguet on their highly cited paper published inCell Cycle

(2011) Catherine Transy   CELL CYCLE

HIV-1 Vpr Induces the K48-Linked Polyubiquitination and Proteasomal Degradation of Target Cellular Proteins To Activate ATR and Promote G2 Arrest

(2010) J.-P. Belzile et al.   JOURNAL OF VIROLOGY

Structure-Function Relationship of Vpr: Biological Implications

(2009) Nelly Morellet et al.   CURRENT HIV RESEARCH

Human Immunodeficiency Virus Type 1 Vpr Modulates Cellular Expression of UNG2 via a Negative Transcriptional Effect

(2009) C. Langevin et al.   JOURNAL OF VIROLOGY

A promiscuous α-helical motif anchors viral hijackers and substrate receptors to the CUL4–DDB1 ubiquitin ligase machinery

(2009) Ti Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Uracil DNA Glycosylase 2 negatively regulates HIV-1 LTR transcription

(2009) David Fenard et al.   NUCLEIC ACIDS RESEARCH

HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain

(2009) Y. Iwatani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cullin 4B-Based UV-Damaged DNA-Binding Protein Ligase Binds to UV-Damaged Chromatin and Ubiquitinates Histone H2A

(2008) J. Guerrero-Santoro et al.   CANCER RESEARCH

HIV-1 Accessory Proteins—Ensuring Viral Survival in a Hostile Environment

(2008) Michael H. Malim et al.   Cell Host & Microbe

HIV-1 Vpr: Mechanisms of G2 arrest and apoptosis

(2008) Joshua L. Andersen et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Assembly with the Cul4A-DDB1DCAF1Ubiquitin Ligase Protects HIV-1 Vpr from Proteasomal Degradation

(2008) Erwann Le Rouzic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Immunodeficiency Virus Type 1 Vpr Binds to the N Lobe of the Wee1 Kinase Domain and Enhances Kinase Activity for Cdc2

(2008) M. Kamata et al.   JOURNAL OF VIROLOGY

Human APOBEC3G Can Restrict Retroviral Infection in Avian Cells and Acts Independently of both UNG and SMUG1

(2008) M.-A. Langlois et al.   JOURNAL OF VIROLOGY

The DNA Deaminase Activity of Human APOBEC3G Is Required for Ty1, MusD, and Human Immunodeficiency Virus Type 1 Restriction

(2008) A. J. Schumacher et al.   JOURNAL OF VIROLOGY