Latent HIV-1 Infection Occurs in Multiple Subsets of Hematopoietic Progenitor Cells and Is Reversed by NF- B Activation

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

(2012) Liang Shan et al.   IMMUNITY

HIV-1 DNA Is Detected in Bone Marrow Populations Containing CD4+ T Cells but Is not Found in Purified CD34+ Hematopoietic Progenitor Cells in Most Patients on Antiretroviral Therapy

(2012) Christine M. Durand et al.   JOURNAL OF INFECTIOUS DISEASES

Hematopoietic Precursor Cells Isolated From Patients on Long-term Suppressive HIV Therapy Did Not Contain HIV-1 DNA

(2012) Lina Josefsson et al.   JOURNAL OF INFECTIOUS DISEASES

A Flexible Model of HIV-1 Latency Permitting Evaluation of Many Primary CD4 T-Cell Reservoirs

(2012) Kara G. Lassen et al.   PLoS One

HIV-1 Utilizes the CXCR4 Chemokine Receptor to Infect Multipotent Hematopoietic Stem and Progenitor Cells

(2011) Christoph C. Carter et al.   Cell Host & Microbe

Characterization of Human Immunodeficiency Virus Type 1 (HIV-1) Diversity and Tropism in 145 Patients With Primary HIV-1 Infection

(2011) P. Rieder et al.   CLINICAL INFECTIOUS DISEASES

Presence of CXCR4-Using HIV-1 in Patients With Recently Diagnosed Infection: Correlates and Evidence for Transmission

(2011) Kristen Chalmet et al.   JOURNAL OF INFECTIOUS DISEASES

T-Cell Receptor Signaling Enhances Transcriptional Elongation from Latent HIV Proviruses by Activating P-TEFb through an ERK-Dependent Pathway

(2011) Young Kyeung Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

(2011) F. Notta et al.   SCIENCE

Homeostatic Proliferation Fails to Efficiently Reactivate HIV-1 Latently Infected Central Memory CD4+ T Cells

(2011) Alberto Bosque et al.   PLoS Pathogens

Detection of quasispecies variants predicted to use CXCR4 by ultra-deep pyrosequencing during early HIV infection

(2010) Isabella Abbate et al.   AIDS

Establishment of HIV Latency in Primary CD4+ Cells Is due to Epigenetic Transcriptional Silencing and P-TEFb Restriction

(2010) M. Tyagi et al.   JOURNAL OF VIROLOGY

Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development

(2010) Sergei Doulatov et al.   NATURE IMMUNOLOGY

HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs

(2010) Christoph C Carter et al.   NATURE MEDICINE

HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals

(2010) D. Trono et al.   SCIENCE

Hematopoietic stem/precursor cells as HIV reservoirs

(2010) Lucy A McNamara et al.   Current Opinion in HIV and AIDS

Short Communication: Activation of Latent HIV Type 1 Gene Expression by Suberoylanilide Hydroxamic Acid (SAHA), an HDAC Inhibitor Approved for Use to Treat Cutaneous T Cell Lymphoma

(2009) Leonard C. Edelstein et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Suberoylanilide Hydroxamic Acid Reactivates HIV from Latently Infected Cells

(2009) Xavier Contreras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4+ T lymphocytes

(2009) Rajesh Ramakrishnan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Determinants of the Establishment of Human Immunodeficiency Virus Type 1 Latency

(2009) A. Duverger et al.   JOURNAL OF VIROLOGY

Analysis of Human Immunodeficiency Virus Type 1 Viremia and Provirus in Resting CD4+ T Cells Reveals a Novel Source of Residual Viremia in Patients on Antiretroviral Therapy

(2009) T. P. Brennan et al.   JOURNAL OF VIROLOGY

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

CpG Methylation Controls Reactivation of HIV from Latency

(2009) Jana Blazkova et al.   PLoS Pathogens

Epigenetic Regulation of HIV-1 Latency by Cytosine Methylation

(2009) Steven E. Kauder et al.   PLoS Pathogens

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

(2008) A. Bosque et al.   BLOOD

Low-level plasma HIVs in patients on prolonged suppressive highly active antiretroviral therapy are produced mostly by cells other than CD4 T-cells

(2008) Gautam K. Sahu et al.   JOURNAL OF MEDICAL VIROLOGY

The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors

(2008) Yelena L Pobezinskaya et al.   NATURE IMMUNOLOGY

Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy

(2008) S. Palmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hide-and-Seek: The Challenge of Viral Persistence in HIV-1 Infection

(2007) Luc Geeraert et al.   Annual Review of Medicine