Article
Nutrition & Dietetics
Alda Attina, Claudia Leggeri, Rita Paroni, Francesca Pivari, Michele Dei Cas, Alessandra Mingione, Maria Dri, Marco Marchetti, Laura Di Renzo
Summary: Fasting is a key topic in the Nutritional Era, involving catabolism of lipids, proteins, and carbohydrates to maintain blood glucose levels and promote longevity. While studies show benefits, there is a lack of safe fasting protocols for physicians to prescribe. Research needs to focus on specific guidelines to enhance effectiveness and improve body composition.
Article
Oncology
Katherine K. Clifton, Cynthia X. Ma, Luigi Fontana, Lindsay L. Peterson
Summary: Intermittent fasting (IF) has gained popularity as a potential anticarcinogenic strategy, but its effects on cancer patients remain unclear without high-quality randomized clinical trials. More research is needed to determine the risks and benefits of IF for cancer patients before it can be recommended outside of clinical trials.
CA-A CANCER JOURNAL FOR CLINICIANS
(2021)
Review
Endocrinology & Metabolism
Dana Abdelrahim, MoezAlIslam E. Faris, Mohamed Hassanein, Ayman Z. Shakir, Ayesha M. Yusuf, Aljohara S. Almeneessier, Ahmed S. BaHammam
Summary: This study reviewed the scientific evidence on hypoglycemic events (HE) occurrence among patients with type 2 diabetes (T2DM) fasting during Ramadan, as well as the effects of different moderators on HE incidence. Results showed that non-sulfonylureas hypoglycemic medications were more effective in reducing the incidence of HE, with various factors such as sex, geographical location, body indicators, season, dietary behaviors, fasting duration, time since diagnosis, and pre-fasting education associated with experiencing HE during Ramadan.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Oncology
Ezzeldin M. Ibrahim, Meteb H. Al-Foheidi, Mubarak M. Al-Mansour
Summary: Dietary interventions have a significant impact on body metabolism and can hinder cancer growth and progression while enhancing the efficacy of chemotherapy and radiation therapy. Although current clinical trials have small sample sizes, they have shown clinical benefits for cancer patients.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Agriculture, Dairy & Animal Science
Thunyaporn Phungviwatnikul, Anne H. Lee, Sara E. Belchik, Jan S. Suchodolski, Kelly S. Swanson
Summary: The study found that restricted feeding of a high-protein, high-fiber diet and weight loss can help overweight dogs reduce fat mass, decrease levels of inflammatory markers and triglycerides, and modulate fecal bacterial populations and activity.
JOURNAL OF ANIMAL SCIENCE
(2022)
Review
Nutrition & Dietetics
Mehdi Sadeghian, Sepideh Rahmani, Saman Khalesi, Ehsan Hejazi
Summary: Fasting may improve the response of tumor cells to chemotherapy through multiple mechanisms, protect normal cells, and enhance the effectiveness of chemotherapy. However, with limited human trials, more human studies with sufficient sample size and follow-ups are needed to confirm these findings.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Anika M. Hartmann, Melanie Dell'Oro, Michaela Spoo, Jan Moritz Fischer, Nico Steckhan, Michael Jeitler, Thomas Haeupl, Farid Kandil, Andreas Michalsen, Daniela A. Koppold-Liebscher, Christian S. Kessler
Summary: This study compared the effects of fasting followed by a plant-based diet and a traditional German Society for Nutrition diet on rheumatoid arthritis. The results showed that the fasting group had faster improvement, but there was no significant difference in function and disability after 12 weeks between the two groups. Both dietary approaches had positive effects on RA disease activity and cardiovascular risk factors.
FRONTIERS IN NUTRITION
(2022)
Review
Cell Biology
Paolo Di Giosia, Cosimo Andrea Stamerra, Paolo Giorgini, Tannaz Jamialahamdi, Alexandra E. Butler, Amirhossein Sahebkar
Summary: This article reviews the interaction between inflammaging and nutrition, focusing on the role of the Mediterranean diet, gut microbiota, and calorie restriction in reducing systemic inflammation and improving clinical outcomes.
AGEING RESEARCH REVIEWS
(2022)
Article
Oncology
Mona Alidadi, Maciej Banach, Paul C. Guest, Simona Bo, Tannaz Jamialahmadi, Amirhossein Sahebkar
Summary: Caloric restriction (CR) and fasting have shown potential anticancer effects by reducing tumor progression, enhancing death of cancer cells, and elevating the effectiveness and tolerability of chemo- and radiotherapies. However, clinical studies on the potential of CR and fasting in cancer treatment are scarce and inconsistent, requiring further investigation to clarify their impact.
SEMINARS IN CANCER BIOLOGY
(2021)
Review
Nutrition & Dietetics
Lihu Gu, Rongrong Fu, Jiaze Hong, Haixiang Ni, Kepin Yu, Haiying Lou
Summary: This study found that intermittent fasting (IF) was more beneficial in reducing body weight, waist circumference, and fat mass compared to non-intervention diet. IF also effectively improved insulin resistance and blood lipid conditions compared with non-intervention diets. However, IF showed less benefit over caloric restriction (CR).
FRONTIERS IN NUTRITION
(2022)
Review
Endocrinology & Metabolism
Caner Ozyildirim, Asli Ucar
Summary: Overweight and obesity are prevalent public health issues worldwide and increase the risk of various metabolic diseases. Intermittent fasting is an effective and safe method of weight loss, which could also have therapeutic effects on obesity-related diseases.
MINERVA ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Baptiste Gramont, Martin Killian, Elodie Bernard, Laure Martinez, Sebastien Bruel, Bogdan Galusca, Nathalie Barth, Thomas Celarier
Summary: This study investigated the knowledge, practices, and acceptability of therapeutic fasting in subjects aged 65 years and over. The results showed that a majority of elderly individuals are interested in and willing to try therapeutic fasting if it is proven beneficial, particularly in terms of reducing the burden of chronic diseases. These findings lay the groundwork for future clinical trials evaluating therapeutic fasting in elderly subjects.
Review
Nutrition & Dietetics
Joana M. Correia, Ines Santos, Pedro Pezarat-Correia, Analiza M. Silva, Goncalo V. Mendonca
Summary: The study found that non-Ramadan intermittent fasting can effectively reduce body weight, body mass index, and absolute fat mass, while Ramadan intermittent fasting, despite being accompanied by dehydration, can also effectively reduce body weight and relative fat mass. Overall, non-Ramadan intermittent fasting appears to be more effective in improving overall body composition.
FRONTIERS IN NUTRITION
(2021)
Article
Nutrition & Dietetics
Alex E. Mohr, Paniz Jasbi, Devin A. Bowes, Blake Dirks, Corrie M. Whisner, Karen M. Arciero, Michelle Poe, Haiwei Gu, Eric Gumpricht, Karen L. Sweazea, Paul J. Arciero
Summary: Nutritional interventions, such as intermittent fasting, show potential benefits in addressing obesity and cardiometabolic dysfunction by modulating body weight regulation, gut microbiome, and plasma metabolome. This study analyzed the impact of a four-week intermittent fasting intervention on overweight and obese adults and found that it modestly influenced gut microbiome community structure and plasma metabolome, suggesting its viability as a nutritional intervention strategy.
FRONTIERS IN NUTRITION
(2022)
Article
Cell Biology
Xiaoping Zhang, Yong Zhong, Lin Liu, Chengyou Jia, Haidong Cai, Jianshe Yang, Bo Wu, Zhongwei Lv
Summary: The study found that fasting can inhibit glycolysis and mitochondrial function in papillary thyroid carcinoma (PTC). Fasting significantly increases the expression of lncRNA PRKCQ-AS1 in PTC cells, which leads to suppression of glycolysis and reduced mitochondrial function. PRKCQ-AS1 interacts with IGF2BPs and enhances the expression of PRMT7 mRNA, thereby regulating glycolysis and mitochondrial function in PTC and inhibiting tumor growth.
CELL DEATH & DISEASE
(2023)
Review
Toxicology
David Rouquie, Marjoke Heneweer, Jane Botham, Hans Ketelslegers, Lauren Markell, Thomas Pfister, Winfried Steiling, Volker Strauss, Christa Hennes
CRITICAL REVIEWS IN TOXICOLOGY
(2015)
Article
Food Science & Technology
R. Buesen, S. Schulte, V. Strauss, S. Treumann, M. Becker, S. Groeters, S. Carvalho, B. van Ravenzwaay
FOOD AND CHEMICAL TOXICOLOGY
(2015)
Article
Toxicology
Burkhard Flick, Steffen Schneider, Stephanie Melching-Kollmuss, Karma C. Fussell, Sibylle Groters, Roland Buesen, Volker Strauss, Bennard van Ravenzwaay
ARCHIVES OF TOXICOLOGY
(2017)
Article
Toxicology
Stephanie Melching-Kollmuss, Karma C. Fussell, Steffen Schneider, Roland Buesen, Sibylle Groeters, Volker Strauss, Bennard van Ravenzwaay
ARCHIVES OF TOXICOLOGY
(2017)
Article
Toxicology
Thomas Hofmann, Lan Ma-Hock, Volker Strauss, Silke Treumann, Maria Rey Moreno, Nicole Neubauer, Wendel Wohlleben, Sibylle Groeters, Karin Wiench, Ulrich Veith, Wera Teubner, Bennard van Ravenzwaay, Robert Landsiedel
INHALATION TOXICOLOGY
(2016)
Article
Medicine, Legal
Nigel P. Moore, Manon Beekhuijzen, Peter J. Boogaard, Jennifer E. Foreman, Colin M. North, Christine Palermo, Steffen Schneider, Volker Strauss, Bennard van Ravenzwaay, Alan Poole
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2016)
Article
Medicine, Legal
B. van Ravenzwaay, S. Sperber, O. Lemke, E. Fabian, F. Faulhammer, H. Kamp, W. Mellert, V. Strauss, A. Strigun, E. Peter, M. Spitzer, T. Walk
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2016)
Article
Toxicology
E. Fabian, N. Bordag, M. Herold, H. Kamp, G. Krennrich, R. Looser, L. Ma-Hock, W. Mellert, G. Montoya, E. Peter, A. Prokudin, M. Spitzer, V. Strauss, T. Walk, R. Zbranek, B. van Ravenzwaay
TOXICOLOGY LETTERS
(2016)
Article
Medicine, Research & Experimental
Hao Zhu, Mounir Bouhifd, Elizabeth Donley, Laura Egnash, Nicole Kleinstreuer, E. Dinant Kroese, Zhichao Liu, Thomas Luechtefeld, Jessica Palmer, David Pamies, Jie Shen, Volker Strauss, Shengde Wu, Thomas Hartung
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
(2016)
Article
Toxicology
Volker Strauss, Maria Cecilia Rey Moreno, Jeanette Vogt, Martina Dammann, Steffen Schneider, Sibylle Groeters, Bennard van Ravenzwaay
TOXICOLOGY MECHANISMS AND METHODS
(2017)
Article
Toxicology
Volker Strauss, Maria Cecilia Rey Moreno, Jeanette Vogt, Martina Dammann, Steffen Schneider, Sibylle Groeters, Bennard van Ravenzwaay
TOXICOLOGY MECHANISMS AND METHODS
(2017)
Article
Pharmacology & Pharmacy
C. Behr, S. Sperber, X. Jiang, V. Strauss, H. Kamp, T. Walk, M. Herold, K. Beekmann, I. M. C. M. Rietjens, B. Van Ravenzwaay
TOXICOLOGY AND APPLIED PHARMACOLOGY
(2018)
Article
Toxicology
Volker Strauss, Susanne N. Kolle, Naveed Honarvar, Martina Dammann, Sibylle Groeters, Frank Faulhammer, Robert Landsiedel, Bennard van Ravenzwaay
JOURNAL OF APPLIED TOXICOLOGY
(2015)
Article
Toxicology
Steffen Schneider, Karma C. Fussell, Stephanie Melching-Kollmuss, Roland Buesen, Sibylle Groeters, Volker Strauss, Xiaoqi Jiang, Bennard van Ravenzwaay
ARCHIVES OF TOXICOLOGY
(2017)
Article
Toxicology
C. Behr, H. Kamp, E. Fabian, G. Krennrich, W. Mellert, E. Peter, V. Strauss, T. Walk, I. M. C. M. Rietjens, B. van Ravenzwaay
ARCHIVES OF TOXICOLOGY
(2017)