The Role of Autophagy in Usnic Acid-Induced Toxicity in Hepatic Cells

Acute Liver Failure Caused by ‘Fat Burners’ and Dietary Supplements: A Case Report and Literature Review

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Sertraline induces endoplasmic reticulum stress in hepatic cells

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Blocking autophagy enhances the apoptosis effect of bufalin on human hepatocellular carcinoma cells through endoplasmic reticulum stress and JNK activation

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Functions of autophagy in normal and diseased liver

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Activation of autophagy by globular adiponectin attenuates ethanol-induced apoptosis in HepG2 cells: Involvement of AMPK/FoxO3A axis

(2013) Saroj Nepal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Samsoeum, a traditional herbal medicine, elicits apoptotic and autophagic cell death by inhibiting Akt/mTOR and activating the JNK pathway in cancer cells

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p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

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Protective effects of gomisin A isolated from Schisandra chinensis against CCl4-induced hepatic and renal injury

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Sertraline, an Antidepressant, Induces Apoptosis in Hepatic Cells Through the Mitogen-Activated Protein Kinase Pathway

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Mechanism study of goldenseal-associated DNA damage

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Protein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity

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A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells

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Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells

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Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK

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Mitochondrial Dysfunction Induced by Sertraline, an Antidepressant Agent

(2012) Yan Li et al.   TOXICOLOGICAL SCIENCES

The crosstalk between autophagy and apoptosis: where does this lead?

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HMGB1 regulates autophagy through increasing transcriptional activities of JNK and ERK in human myeloid leukemia cells

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Assessment of usnic acid toxicity in rat primary hepatocytes using 13C isotopomer distribution analysis of lactate, glutamate and glucose

(2011) Bakary J. Sonko et al.   FOOD AND CHEMICAL TOXICOLOGY

Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy

(2011) Nadezda Apostolova et al.   HEPATOLOGY

Activation of autophagy protects against acetaminophen-induced hepatotoxicity

(2011) Hong-Min Ni et al.   HEPATOLOGY

Effects of usnic acid exposure on human hepatoblastoma HepG2 cells in culture

(2011) Saura C. Sahu et al.   JOURNAL OF APPLIED TOXICOLOGY

Loss of autophagy promotes murine acetaminophen hepatotoxicity

(2011) Yuki Igusa et al.   JOURNAL OF GASTROENTEROLOGY

c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells

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Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

(2010) L. Guo et al.   DRUG METABOLISM AND DISPOSITION

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

(2010) Wen–Xing Ding et al.   GASTROENTEROLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Review of Usnic Acid andUsnea BarbataToxicity

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