Effects of usnic acid exposure on human hepatoblastoma HepG2 cells in culture

Bile Acids Induce Inflammatory Genes in Hepatocytes

(2011) Katryn Allen et al.   AMERICAN JOURNAL OF PATHOLOGY

Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress

(2010) Marc Birringer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Comparative hepatotoxicity of deoxynivalenol in rat, mouse and human liver cells in culture

(2010) Saura C. Sahu et al.   JOURNAL OF APPLIED TOXICOLOGY

Evaluation of Developmental Toxicant Identification Using Gene Expression Profiling in Embryonic Stem Cell Differentiation Cultures

(2010) Dorien A. M. van Dartel et al.   TOXICOLOGICAL SCIENCES

Role of Oxidative Metabolism in the Effect of Valproic Acid on Markers of Cell Viability, Necrosis, and Oxidative Stress in Sandwich-Cultured Rat Hepatocytes

(2010) Tony K. L. Kiang et al.   TOXICOLOGICAL SCIENCES

Effect of Size Fractionation on the Toxicity of Amosite and Libby Amphibole Asbestos

(2010) Kelly E. Duncan et al.   TOXICOLOGICAL SCIENCES

Comparison of HepG2 and HepaRG by Whole-Genome Gene Expression Analysis for the Purpose of Chemical Hazard Identification

(2010) Danyel G. J. Jennen et al.   TOXICOLOGICAL SCIENCES

Small-Molecule Targeting of the Mitochondrial Compartment with an Endogenously Cleaved Reversible Tag

(2009) Jens Ripcke et al.   CHEMBIOCHEM

Genomewide Analysis of Aryl Hydrocarbon Receptor Binding Targets Reveals an Extensive Array of Gene Clusters that Control Morphogenetic and Developmental Programs

(2009) Maureen A. Sartor et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Toxicity Testing in the 21st Century: A View from the Chemical Industry

(2009) James S. Bus et al.   TOXICOLOGICAL SCIENCES

S-Adenosylhomocysteine Promotes the Invasion of C6 Glioma Cells via Increased Secretion of Matrix Metalloproteinase-2 in Murine Microglial BV2 Cells

(2009) Hung-Chi Lin et al.   TOXICOLOGICAL SCIENCES

Pragmatic Challenges for the Vision of Toxicity Testing in the 21st Century in a Regulatory Context: Another Ames Test? …or a New Edition of “the Red Book”?

(2009) Bette Meek et al.   TOXICOLOGICAL SCIENCES

Effects of 18 Perfluoroalkyl Compounds on mRNA Expression in Chicken Embryo Hepatocyte Cultures

(2009) Nathan J. Hickey et al.   TOXICOLOGICAL SCIENCES

Valproic Acid–Induced Deregulation In Vitro of Genes Associated In Vivo with Neural Tube Defects

(2009) Måns Jergil et al.   TOXICOLOGICAL SCIENCES

Iron-Induced Oxidative Injury Differentially Regulates PI3K/Akt/GSK3β Pathway in Synaptic Endings from Adult and Aged Rats

(2009) Romina María Uranga et al.   TOXICOLOGICAL SCIENCES

Long-Term Exposure to Zidovudine Delays Cell Cycle Progression, Induces Apoptosis, and Decreases Telomerase Activity in Human Hepatocytes

(2009) Jia-Long Fang et al.   TOXICOLOGICAL SCIENCES

Inhibition of UV-C Light–Induced Apoptosis in Liver Cells by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

(2009) Martin Chopra et al.   TOXICOLOGICAL SCIENCES

Dynamic Nature of Alterations in the Endocrine System of Fathead Minnows Exposed to the Fungicide Prochloraz

(2009) Gerald T. Ankley et al.   TOXICOLOGICAL SCIENCES

Are In Vitro Tests Suitable for Regulatory Use?

(2009) Thomas Hartung et al.   TOXICOLOGICAL SCIENCES

Decreased Expression of the Voltage-Dependent Anion Channel in Differentiated PC-12 and SH-SY5Y Cells Following Low-Level Pb Exposure

(2009) John M. Prins et al.   TOXICOLOGICAL SCIENCES

Cellular Stress Response Pathway System as a Sentinel Ensemble in Toxicological Screening

(2009) Steven O. Simmons et al.   TOXICOLOGICAL SCIENCES

Altered regulation of Prox1-gene-expression in liver tumors

(2008) Jozsef Dudas et al.   BMC CANCER

A Cell-based High-throughput Assay System Reveals Modulation of Oxidative and Nonoxidative Glucose Metabolism due to Commonly Used Organic Solvents

(2008) S. Zimmermann et al.   HORMONE AND METABOLIC RESEARCH

Rat liver clone-9 cells in culture as a model for screening hepatotoxic potential of food-related products: hepatotoxicity of deoxynivalenol

(2008) Saura C. Sahu et al.   JOURNAL OF APPLIED TOXICOLOGY

The Genomic Response of a Human Uterine Endometrial Adenocarcinoma Cell Line to 17α-Ethynyl Estradiol

(2008) Jorge M. Naciff et al.   TOXICOLOGICAL SCIENCES

Lung Development in the Holtzman Rat is Adversely Affected by Gestational Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

(2008) Kevin M. Kransler et al.   TOXICOLOGICAL SCIENCES

A Concentration Addition Model for the Activation of the Constitutive Androstane Receptor by Xenobiotic Mixtures

(2008) William S. Baldwin et al.   TOXICOLOGICAL SCIENCES

Toxicity Testing in the 21st Century: Bringing the Vision to Life

(2008) Melvin E. Andersen et al.   TOXICOLOGICAL SCIENCES

Nickel and the Microbial Toxin, MALP-2, Stimulate Proangiogenic Mediators from Human Lung Fibroblasts via a HIF-1α and COX-2–Mediated Pathway

(2008) Kelly A. Brant et al.   TOXICOLOGICAL SCIENCES

Effects of fibrates, anti-inflammatory drugs and antidepressants in the fish hepatoma cell line PLHC-1: Cytotoxicity and interactions with cytochrome P450 1A

(2008) Rémi Thibaut et al.   TOXICOLOGY IN VITRO

Metabolism and related human risk factors for hepatic damage by usnic acid containing nutritional supplements

(2008) R. S. Foti et al.   XENOBIOTICA

Effect of Pyrethrins on cytochrome P450 forms in cultured rat and human hepatocytes

(2007) Roger J. Price et al.   TOXICOLOGY