Systematic Mapping of Protein Mutational Space by Prolonged Drift Reveals the Deleterious Effects of Seemingly Neutral Mutations
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Title
Systematic Mapping of Protein Mutational Space by Prolonged Drift Reveals the Deleterious Effects of Seemingly Neutral Mutations
Authors
Keywords
Nonsense mutation, Deletion mutation, Mutation, Substitution mutation, Point mutation, Mutagenesis, Nucleotide sequencing, Plasmid construction
Journal
PLoS Computational Biology
Volume 11, Issue 8, Pages e1004421
Publisher
Public Library of Science (PLoS)
Online
2015-08-15
DOI
10.1371/journal.pcbi.1004421
References
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