Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma

Differential Roles of Insulin-like Growth Factor Receptor- and Insulin Receptor-mediated Signaling in the Phenotypes of Hepatocellular Carcinoma Cells

(2015) Ya-Wen Chen et al.   NEOPLASIA

How to get the most from microarray data: advice from reverse genomics

(2014) Ivan P Gorlov et al.   BMC GENOMICS

Hepatic Fibrosis and the Microenvironment: Fertile Soil for Hepatocellular Carcinoma Development

(2014) Michael C. Wallace et al.   GENE EXPRESSION

Cylindromatosis gene CYLD regulates hepatocyte growth factor expression in hepatic stellate cells through interaction with histone deacetylase 7

(2014) Rajeswara R. Pannem et al.   HEPATOLOGY

Context-dependent Cooperation between Nuclear Factor κB (NF-κB) and the Glucocorticoid Receptor at aTNFAIP3Intronic Enhancer

(2014) Mohammed O. Altonsy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pregnancy-associated plasma protein A regulates mitosis and is epigenetically silenced in breast cancer

(2014) Marco Loddo et al.   JOURNAL OF PATHOLOGY

Inferring microRNA–mRNA causal regulatory relationships from expression data

(2013) Thuc Duy Le et al.   BIOINFORMATICS

Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma

(2013) Virginia Hernandez–Gea et al.   GASTROENTEROLOGY

Met as a therapeutic target in HCC: Facts and hopes

(2013) Silvia Giordano et al.   JOURNAL OF HEPATOLOGY

Hepatic stellate cells—the pericytes in the liver

(2013) Claus Hellerbrand   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Characterization of Niemann-Pick Type C2 Protein Expression in Multiple Cancers Using a Novel NPC2 Monoclonal Antibody

(2013) Yi-Jen Liao et al.   PLoS One

Tumor and its microenvironment: A synergistic interplay

(2013) Veronica Catalano et al.   SEMINARS IN CANCER BIOLOGY

Causal stability ranking

(2012) Daniel J. Stekhoven et al.   BIOINFORMATICS

PAPP-A in cardiac and non-cardiac conditions

(2012) Yuehua Li et al.   CLINICA CHIMICA ACTA

Interaction of the Hepatitis B Spliced Protein with Cathepsin B Promotes Hepatoma Cell Migration and Invasion

(2012) W.-N. Chen et al.   JOURNAL OF VIROLOGY

High-level expression of periostin is closely related to metastatic potential and poor prognosis of hepatocellular carcinoma

(2012) Yang Lv et al.   MEDICAL ONCOLOGY

Protein Secretion Is Required for Pregnancy-Associated Plasma Protein-A to Promote Lung Cancer Growth In Vivo

(2012) Hong Pan et al.   PLoS One

Key questions and answers about pregnancy-associated plasma protein-A

(2012) Cheryl A. Conover   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Model-based gene set analysis for Bioconductor

(2011) S. Bauer et al.   BIOINFORMATICS

HTSanalyzeR: an R/Bioconductor package for integrated network analysis of high-throughput screens

(2011) X. Wang et al.   BIOINFORMATICS

Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression

(2011) Paolo Cirri et al.   CANCER AND METASTASIS REVIEWS

Lung Cancer Signatures in Plasma Based on Proteome Profiling of Mouse Tumor Models

(2011) Ayumu Taguchi et al.   CANCER CELL

Hepatic stellate cells stimulate HCC cell migration via laminin-5 production

(2011) Angela Santamato et al.   CLINICAL SCIENCE

Overexpression of Pregnancy-Associated Plasma Protein-A in Ovarian Cancer Cells Promotes Tumor Growthin Vivo

(2011) Henning B. Boldt et al.   ENDOCRINOLOGY

CD133+ liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling

(2011) Kwan Ho Tang et al.   HEPATOLOGY

Activated hepatic stellate cells promote hepatocellular carcinoma development in immunocompetent mice

(2011) Wenxiu Zhao et al.   INTERNATIONAL JOURNAL OF CANCER

Targeting insulin-like growth factor axis in hepatocellular carcinoma

(2011) Jennifer Wu et al.   Journal of Hematology & Oncology

A member of the mitogen-activated protein 3-kinase family is involved in the regulation of plant vacuolar glucose uptake

(2011) Karina Wingenter et al.   PLANT JOURNAL

Reduced Expression of Fibroblast Growth Factor Receptor 2IIIb in Hepatocellular Carcinoma Induces a More Aggressive Growth

(2010) Thomas Amann et al.   AMERICAN JOURNAL OF PATHOLOGY

BioNet: an R-Package for the functional analysis of biological networks

(2010) D. Beisser et al.   BIOINFORMATICS

Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase

(2010) Thorsten Gantke et al.   CELL RESEARCH

Stability selection

(2010) Nicolai Meinshausen et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Longevity and Age-Related Pathology of Mice Deficient in Pregnancy-Associated Plasma Protein-A

(2010) Cheryl A. Conover et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Predicting causal effects in large-scale systems from observational data

(2010) Marloes H Maathuis et al.   NATURE METHODS

Oncoproteomic Analysis Reveals Co-Upregulation of RELA and STAT5 in Carboplatin Resistant Ovarian Carcinoma

(2010) Natini Jinawath et al.   PLoS One

Cholesterol trafficking is required for mTOR activation in endothelial cells

(2010) J. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peritumoral Activated Hepatic Stellate Cells Predict Poor Clinical Outcome in Hepatocellular Carcinoma After Curative Resection

(2009) Min-Jie Ju et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Estimating high-dimensional intervention effects from observational data

(2009) Marloes H. Maathuis et al.   ANNALS OF STATISTICS

Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma

(2009) Thomas Amann et al.   CANCER SCIENCE

Regulatory feedback loop between NF-κB and MCP-1-induced protein 1 RNase

(2009) Lukasz Skalniak et al.   FEBS Journal

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions

(2009) A Gualberto et al.   ONCOGENE

NF-kappa B genes have a major role in Inflammatory Breast Cancer

(2008) Florence Lerebours et al.   BMC CANCER

Reactivation of the insulin-like growth factor-II signaling pathway in human hepatocellular carcinoma

(2008) Kai Breuhahn   WORLD JOURNAL OF GASTROENTEROLOGY