New players in haemostasis and thrombosis

Antithrombotic Effect of Antisense Factor XI Oligonucleotide Treatment in Primates

(2013) Jeffrey R. Crosby et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels

(2013) S. Ghosh et al.   BLOOD

Tumor-derived tissue factor-positive microparticles and venous thrombosis in cancer patients

(2013) J. E. Geddings et al.   BLOOD

Time-dependent degradation and tissue factor addition mask the ability of platelet polyphosphates in activating factor XII-mediated coagulation

(2013) K. F. Nickel et al.   BLOOD

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice

(2013) K. Martinod et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Red cell-derived microparticles (RMP) as haemostatic agent

(2013) Max Johansen et al.   THROMBOSIS AND HAEMOSTASIS

Factor XIIa inhibition by Infestin-4: in vitro mode of action and in vivo antithrombotic benefit

(2013) Yiming Xu et al.   THROMBOSIS AND HAEMOSTASIS

Plasma DNA is elevated in patients with deep vein thrombosis

(2013) Jose Antonio Diaz et al.   Journal of Vascular Surgery-Venous and Lymphatic Disorders

Neutrophil Extracellular Trap (NET) Impact on Deep Vein Thrombosis

(2012) Tobias A. Fuchs et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Circulating Nucleosomes and Neutrophil Activation as Risk Factors for Deep Vein Thrombosis

(2012) Maurits L. van Montfoort et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies

(2012) T. A. Fuchs et al.   BLOOD

Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer

(2012) J.-G. Wang et al.   BLOOD

Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation

(2012) J. H. Morrissey et al.   BLOOD

Inhibition of polyphosphate as a novel strategy for preventing thrombosis and inflammation

(2012) S. A. Smith et al.   BLOOD

Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers

(2012) C. D'Souza-Schorey et al.   GENES & DEVELOPMENT

Monocyte tissue factor–dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin

(2012) A. Phillip Owens et al.   JOURNAL OF CLINICAL INVESTIGATION

New insights into the mechanisms of venous thrombosis

(2012) Nigel Mackman   JOURNAL OF CLINICAL INVESTIGATION

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo

(2012) Bryan G Yipp et al.   NATURE MEDICINE

Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones

(2012) Mona Saffarzadeh et al.   PLoS One

Nucleic acid scavengers inhibit thrombosis without increasing bleeding

(2012) S. Jain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice

(2012) Philberta Y. Leung et al.   Translational Stroke Research

Polyphosphate is a cofactor for the activation of factor XI by thrombin

(2011) S. H. Choi et al.   BLOOD

Histones induce rapid and profound thrombocytopenia in mice

(2011) T. A. Fuchs et al.   BLOOD

Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin

(2011) J. Konings et al.   BLOOD

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

(2011) Bence György et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Microparticles in Hemostasis and Thrombosis

(2011) A. Phillip Owens et al.   CIRCULATION RESEARCH

Factor XI and XII as antithrombotic targets

(2011) Felicitas Müller et al.   CURRENT OPINION IN HEMATOLOGY

Nanoscale studies of protein-membrane interactions in blood clotting

(2011) J. H. MORRISSEY et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Differential contributions of monocyte- and platelet-derived microparticles towards thrombin generation and fibrin formation and stability

(2011) M. M. ALEMAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Neutrophil extracellular traps promote deep vein thrombosis in mice

(2011) A. BRILL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Statins in the prevention of venous thromboembolism: A meta-analysis of observational studies

(2011) Menaka Pai et al.   THROMBOSIS RESEARCH

Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk

(2010) H. Zhang et al.   BLOOD

Polyphosphate exerts differential effects on blood clotting, depending on polymer size

(2010) S. A. Smith et al.   BLOOD

Factor XIIa Inhibitor Recombinant Human Albumin Infestin-4 Abolishes Occlusive Arterial Thrombus Formation Without Affecting Bleeding

(2010) Ina Hagedorn et al.   CIRCULATION

Microparticles

(2010) Sebastian F. Mause et al.   CIRCULATION RESEARCH

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Coagulation factor XI as a novel target for antithrombotic treatment

(2010) E. C. LÖWENBERG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

(2010) Steffen Massberg et al.   NATURE MEDICINE

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tissue Factor and Its Measurement in Whole Blood, Plasma, and Microparticles

(2010) Nigel Key et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Tissue factor and thrombosis: The clot starts here

(2010) A. Phillip Owens et al.   THROMBOSIS AND HAEMOSTASIS

Proteomics of microparticles after deep venous thrombosis

(2010) Eduardo Ramacciotti et al.   THROMBOSIS RESEARCH

Tissue Factor in Coagulation

(2009) Saulius Butenas et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Cancer cell–derived microparticles bearing P-selectin glycoprotein ligand 1 accelerate thrombus formation in vivo

(2009) Grace M. Thomas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Randomized Trial of Rosuvastatin in the Prevention of Venous Thromboembolism

(2009) Robert J. Glynn et al.   NEW ENGLAND JOURNAL OF MEDICINE

P-selectin/ PSGL-1 Inhibitors versus enoxaparin in the resolution of venous thrombosis: A meta-analysis

(2009) Eduardo Ramacciotti et al.   THROMBOSIS RESEARCH

Polyphosphate enhances fibrin clot structure

(2008) S. A. Smith et al.   BLOOD

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

(2008) E. I. Tucker et al.   BLOOD

Polyphosphate as a general procoagulant agent

(2008) S. A. SMITH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS