Multiple Roles for Neutrophils in Atherosclerosis

Presence of luminal neutrophil extracellular traps in atherosclerosis

(2012) Remco T. A. Megens et al.   THROMBOSIS AND HAEMOSTASIS

Neutrophil Activation Is Attenuated by High-Density Lipoprotein and Apolipoprotein A-I in In Vitro and In Vivo Models of Inflammation

(2011) Andrew J. Murphy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Human Neutrophil Peptides Mediate Endothelial-Monocyte Interaction, Foam Cell Formation, and Platelet Activation

(2011) Kieran L. Quinn et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Necrotic cell death in atherosclerosis

(2011) Wim Martinet et al.   BASIC RESEARCH IN CARDIOLOGY

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Intravital Microscopy on Atherosclerosis in Apolipoprotein E–Deficient Mice Establishes Microvessels as Major Entry Pathways for Leukocytes to Advanced Lesions

(2011) Einar E. Eriksson   CIRCULATION

Binding of CD40L to Mac-1's I-Domain Involves the EQLKKSKTL Motif and Mediates Leukocyte Recruitment and Atherosclerosis—But Does Not Affect Immunity and Thrombosis in Mice

(2011) Dennis Wolf et al.   CIRCULATION RESEARCH

In vitro and in vivo evidence for the role of elastase shedding of CD163 in human atherothrombosis

(2011) Juan Antonio Moreno et al.   EUROPEAN HEART JOURNAL

Complement C5a inhibition reduces atherosclerosis in ApoE−/− mice

(2011) Helga D. Manthey et al.   FASEB JOURNAL

ApoE controls the interface linking lipids and inflammation in atherosclerosis

(2011) Christian Weber et al.   JOURNAL OF CLINICAL INVESTIGATION

ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

(2011) Andrew J. Murphy et al.   JOURNAL OF CLINICAL INVESTIGATION

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

(2011) Stephen J Galli et al.   NATURE IMMUNOLOGY

Anti-inflammatory therapeutics for the treatment of atherosclerosis

(2011) Israel F. Charo et al.   NATURE REVIEWS DRUG DISCOVERY

Regulation of Endothelial Cell Adhesion Molecule Expression by Mast Cells, Macrophages, and Neutrophils

(2011) Jie Zhang et al.   PLoS One

Neutrophil-Derived Cathelicidin Protects from Neointimal Hyperplasia

(2011) O. Soehnlein et al.   Science Translational Medicine

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Neutrophils and clinical outcomes in patients with acute coronary syndromes and/or cardiac revascularisation

(2011) Luigina Guasti et al.   THROMBOSIS AND HAEMOSTASIS

Monocyte trafficking in acute and chronic inflammation

(2011) Molly A. Ingersoll et al.   TRENDS IN IMMUNOLOGY

Distinct Infiltration of Neutrophils in Lesion Shoulders in ApoE−/− Mice

(2010) Pierre Rotzius et al.   AMERICAN JOURNAL OF PATHOLOGY

High Neutrophil Numbers in Human Carotid Atherosclerotic Plaques Are Associated With Characteristics of Rupture-Prone Lesions

(2010) Mihaela G. Ionita et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Blockade of Interleukin-17A Results in Reduced Atherosclerosis in Apolipoprotein E–Deficient Mice

(2010) Emily Smith et al.   CIRCULATION

Hyperlipidemia-Triggered Neutrophilia Promotes Early Atherosclerosis

(2010) Maik Drechsler et al.   CIRCULATION

Atherosclerotic lesions in mouse and man: is it the same disease?

(2010) Jacob Fog Bentzon et al.   CURRENT OPINION IN LIPIDOLOGY

Neutrophils, from Marrow to Microbes

(2010) Niels Borregaard   IMMUNITY

Targeting granulocyte apoptosis: mechanisms, models, and therapies

(2010) Rodger Duffin et al.   IMMUNOLOGICAL REVIEWS

LL-37 Directs Macrophage Differentiation toward Macrophages with a Proinflammatory Signature

(2010) A. M. van der Does et al.   JOURNAL OF IMMUNOLOGY

The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B

(2010) Marcela Rosas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

(2010) Steffen Massberg et al.   NATURE MEDICINE

Monocytes in atherosclerosis: subsets and functions

(2010) Kevin J. Woollard et al.   Nature Reviews Cardiology

Macrophage Plasticity in Experimental Atherosclerosis

(2010) Jamila Khallou-Laschet et al.   PLoS One

ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

(2010) L. Yvan-Charvet et al.   SCIENCE

Immune and Inflammatory Mechanisms of Atherosclerosis

(2009) Elena Galkina et al.   Annual Review of Immunology

Statins Control Oxidized LDL-Mediated Histone Modifications and Gene Expression in Cultured Human Endothelial Cells

(2009) Philippe Dje N'Guessan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis

(2009) Filip K. Swirski et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of the Migration and Survival of Monocyte Subsets by Chemokine Receptors and Its Relevance to Atherosclerosis

(2009) Emmanuel L. Gautier et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

NADPH Oxidases: Functions and Pathologies in the Vasculature

(2009) Bernard Lassègue et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A response to the letter regarding the pleiotropic effects of fluvastatin on acute inflammatory response and the role of MMP-9 in plaque destabilization and intraplaque hemorrhage

(2009) Kae Nakamura et al.   ATHEROSCLEROSIS

Role of polymorphonuclear neutrophils in atherosclerosis: Current state and future perspectives

(2009) Roberta Baetta et al.   ATHEROSCLEROSIS

Leukocyte count in peripheral arterial disease: A simple, reliable, inexpensive approach to cardiovascular risk prediction

(2009) Giuseppe Giugliano et al.   ATHEROSCLEROSIS

Mechanisms underlying neutrophil-mediated monocyte recruitment

(2009) O. Soehnlein et al.   BLOOD

Myeloid-Related Protein-8/14 Is Critical for the Biological Response to Vascular Injury

(2009) Kevin Croce et al.   CIRCULATION

A Role of Matrix Metalloproteinase-8 in Atherosclerosis

(2009) Ross C. Laxton et al.   CIRCULATION RESEARCH

Functional alterations of myeloid cell subsets in hyperlipidaemia: relevance for atherosclerosis

(2009) Oliver Soehnlein et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Relationship of Thrombus Healing to Underlying Plaque Morphology in Sudden Coronary Death

(2009) Miranda C.A. Kramer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family

(2009) R. D. Ye et al.   PHARMACOLOGICAL REVIEWS

Myeloid cells in atherosclerosis: initiators and decision shapers

(2009) Oliver Soehnlein et al.   Seminars in Immunopathology

Opening the flood-gates: how neutrophil-endothelial interactions regulate permeability

(2009) Matthew R. DiStasi et al.   TRENDS IN IMMUNOLOGY

NETs: a new strategy for using old weapons

(2009) Venizelos Papayannopoulos et al.   TRENDS IN IMMUNOLOGY

Neutrophil granule proteins tune monocytic cell function

(2009) Oliver Soehnlein et al.   TRENDS IN IMMUNOLOGY

Alarmins link neutrophils and dendritic cells

(2009) De Yang et al.   TRENDS IN IMMUNOLOGY

Leukocyte Activation by Triglyceride-Rich Lipoproteins

(2008) Arash Alipour et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ApoE−/−/Lysozyme MEGFP/EGFP mice as a versatile model to study monocyte and neutrophil trafficking in atherosclerosis

(2008) Pierre Rotzius et al.   ATHEROSCLEROSIS

Neutrophil secretion products pave the way for inflammatory monocytes

(2008) O. Soehnlein et al.   BLOOD

Myeloperoxidase Delays Neutrophil Apoptosis Through CD11b/CD18 Integrins and Prolongs Inflammation

(2008) Driss El Kebir et al.   CIRCULATION RESEARCH

C-Reactive Protein Stimulates Myeloperoxidase Release from Polymorphonuclear Cells and Monocytes: Implications for Acute Coronary Syndromes

(2008) U. Singh et al.   CLINICAL CHEMISTRY

Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein

(2008) O. Soehnlein et al.   EUROPEAN RESPIRATORY JOURNAL

Neutrophil primary granule proteins HBP and HNP1–3 boost bacterial phagocytosis by human and murine macrophages

(2008) Oliver Soehnlein et al.   JOURNAL OF CLINICAL INVESTIGATION

The molecular mechanisms of the thrombotic complications of atherosclerosis

(2008) P. Libby   JOURNAL OF INTERNAL MEDICINE

Translating molecular discoveries into new therapies for atherosclerosis

(2008) Daniel J. Rader et al.   NATURE

Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR −/− Mice

(2007) Marcella van Leeuwen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Low dose apolipoprotein A-I rescues carotid arteries from inflammation in vivo

(2007) Rajesh Puranik et al.   ATHEROSCLEROSIS

Primed polymorphonuclear leukocytes constitute a possible link between inflammation and oxidative stress in hyperlipidemic patients

(2007) Rafi Mazor et al.   ATHEROSCLEROSIS

Protective Role of CXC Receptor 4/CXC Ligand 12 Unveils the Importance of Neutrophils in Atherosclerosis

(2007) Alma Zernecke et al.   CIRCULATION RESEARCH